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    MTACP-1 mitochondrial acyl carrier protein 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819070, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MTACP-1
    Official Full Name
    mitochondrial acyl carrier protein 1
    Primary source
    TAIR:AT2G44620
    Locus tag
    AT2G44620
    See related
    Araport:AT2G44620
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F16B22.11; mitochondrial acyl carrier protein 1; MITOCHONDRIAL ACYL CARRIER PROTEIN 1; MTACP1
    Summary
    Encodes a member of the mitochondrial acyl carrier protein (ACP) family. As part of the mitochondrial matrix, it is likely to be involved in fatty acid or lipoic acid biogenesis. Its acylated form is predominantly present in the mitochondrial membrane while the non-acylated form is soluble.
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    Genomic context

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    See MTACP-1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (18414201..18415335)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ras-related small GTP-binding family protein Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene TRIGALACTOSYLDIACYLGLYCEROL-like protein Neighboring gene chloroplast chaperonin 10

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The characterization of a mitochondrial acyl carrier protein isoform isolated from Arabidopsis thaliana. Shintani DK, et al. Plant Physiol, 1994 Apr. PMID 8016262, Free PMC Article
    2. Mitochondrial acyl carrier proteins in Arabidopsis thaliana are predominantly soluble matrix proteins and none can be confirmed as subunits of respiratory Complex I. Meyer EH, et al. Plant Mol Biol, 2007 Jun. PMID 17406791
    3. A ferredoxin bridge connects the two arms of plant mitochondrial complex I. Klusch N, et al. Plant Cell, 2021 Jul 19. PMID 33768254, Free PMC Article
    4. Mitochondrial Fatty Acid Synthase Utilizes Multiple Acyl Carrier Protein Isoforms. Fu X, et al. Plant Physiol, 2020 Jun. PMID 32094306, Free PMC Article
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_130026.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    contributes_to NADH dehydrogenase (ubiquinone) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables acyl carrier activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables acyl carrier activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within fatty acid biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitochondrial electron transport, NADH to ubiquinone IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in mitochondrial matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    part_of respiratory chain complex I IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitochondrial acyl carrier protein 1
    NP_181990.1
    • mitochondrial acyl carrier protein 1 (MTACP-1); FUNCTIONS IN: phosphopantetheine binding, acyl carrier activity, cofactor binding; INVOLVED IN: fatty acid biosynthetic process; LOCATED IN: mitochondrion, mitochondrial matrix; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Phosphopantetheine-binding (InterPro:IPR006163), Acyl carrier protein (ACP) (InterPro:IPR003231), Acyl carrier protein-like (InterPro:IPR009081), Phosphopantetheine attachment site (InterPro:IPR006162); BEST Arabidopsis thaliana protein match is: mitochondrial acyl carrier protein 2 (TAIR:AT1G65290.1); Has 7851 Blast hits to 7848 proteins in 2525 species: Archae - 0; Bacteria - 5315; Metazoa - 204; Fungi - 139; Plants - 352; Viruses - 2; Other Eukaryotes - 1839 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18414201..18415335
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130026.4 → NP_181990.1  mitochondrial acyl carrier protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181990.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P53665
      UniProtKB/TrEMBL
      A0A5S9X6Z9, A0A654F372, Q941B9
      Conserved Domains (1) summary
      cl09936
      Location:32 → 121
      PP-binding; Phosphopantetheine attachment site
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53665.1

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