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    LETM1 LETM1-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825151, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LETM1
    Official Full Name
    LETM1-like protein
    Primary source
    TAIR:AT3G59820
    Locus tag
    AT3G59820
    See related
    Araport:AT3G59820
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtLETM1; leucine zipper-EF-hand-containing transmembrane protein 1
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    Genomic context

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    See LETM1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    15
    Sequence:
    Chromosome: 3; NC_003074.8 (22097979..22102224, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene MAP kinase 10 Neighboring gene stress response protein Neighboring gene Small nuclear ribonucleoprotein family protein Neighboring gene Integrin-linked protein kinase family Neighboring gene allyl alcohol dehydrogenase-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The hydrophobic proteome of mitochondrial membranes from Arabidopsis cell suspensions. Brugière S, et al. Phytochemistry, 2004 Jun. PMID 15276431
    2. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article
    3. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    4. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001035820.3
    NM_001340002.1
    NM_001340003.1
    NM_115844.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribosome binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    LETM1-like protein
    NP_001030897.1
    • LETM1-like protein; LOCATED IN: mitochondrion; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), EF-HAND 2 (InterPro:IPR018249), LETM1-like (InterPro:IPR011685); BEST Arabidopsis thaliana protein match is: LETM1-like protein (TAIR:AT1G65540.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_001319801.1
    • LETM1-like protein; FUNCTIONS IN: calcium ion binding; LOCATED IN: mitochondrion; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), EF-HAND 2 (InterPro:IPR018249), EF-hand-like domain (InterPro:IPR011992), LETM1-like (InterPro:IPR011685); BEST Arabidopsis thaliana protein match is: LETM1-like protein (TAIR:AT1G65540.1); Has 1687 Blast hits to 1622 proteins in 328 species: Archae - 23; Bacteria - 178; Metazoa - 665; Fungi - 245; Plants - 190; Viruses - 5; Other Eukaryotes - 381 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      22097979..22102224 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001340002.1 → NP_001319801.1  LETM1-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VHR5, Q9M1Z2
      Conserved Domains (2) summary
      pfam07766
      Location:208 → 463
      LETM1; LETM1-like protein
      cl08302
      Location:683 → 738
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    2. NM_001340003.1 → NP_001327201.1  LETM1-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VHR5, Q9M1Z2
      Conserved Domains (2) summary
      pfam07766
      Location:208 → 463
      LETM1; LETM1-like protein
      cl08302
      Location:683 → 738
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    3. NM_001035820.3 → NP_001030897.1  LETM1-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001030897.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VHR5, F4J9G6
      Conserved Domains (1) summary
      pfam07766
      Location:208 → 463
      LETM1; LETM1-like protein

    4. NM_115844.4 → NP_191541.1  LETM1-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191541.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VHR5, Q9M1Z2
      Conserved Domains (2) summary
      pfam07766
      Location:208 → 463
      LETM1; LETM1-like protein
      cl08302
      Location:683 → 738
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    Nucleotide Protein
    Heading Accession and Version

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