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    slif slimfast [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40510, updated on 9-Dec-2024

    Summary

    Official Symbol
    slifprovided by FlyBase
    Official Full Name
    slimfastprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037203
    Locus tag
    Dmel_CG11128
    See related
    AllianceGenome:FB:FBgn0037203
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11128; Dmel\CG11128; Slif; SLIF; SLIMFAST
    Summary
    Enables basic amino acid transmembrane transporter activity. Involved in amino acid import across plasma membrane; lipid homeostasis; and regulation of growth. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including anterior-posterior subdivision of organism; embryonic salivary gland duct; embryonic/larval fat body; embryonic/larval salivary gland common duct; and gland. Orthologous to human SLC7A1 (solute carrier family 7 member 1); SLC7A2 (solute carrier family 7 member 2); and SLC7A3 (solute carrier family 7 member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See slif in Genome Data Viewer
    Location:
    80B2-80B2; 3-47 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (22881045..22893821)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (22874145..22886921)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR45968 Neighboring gene uncharacterized protein Neighboring gene Chromator Neighboring gene antisense RNA:CR45970 Neighboring gene Suppressor of stem-loop mutation Neighboring gene long non-coding RNA:CR44688 Neighboring gene long non-coding RNA:CR44689

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    mobile_element

    • Loc: 22883443-22883529 mobile_element_type = transposon:INE-1{}2694
    • Loc: 22884585-22884738 mobile_element_type = transposon:INE-1{}2695
    • Loc: 22890587-22890811 mobile_element_type = transposon:INE-1{}2700

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    located_in membrane  
    is_active_in plasma membrane  
    located_in plasma membrane PubMed 

    General protein information

    Preferred Names
    slimfast
    Names
    CG11128-PA
    CG11128-PB
    CG11128-PC
    slif-PA
    slif-PB
    slif-PC
    slim fast

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      22881045..22893821
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168977.2 → NP_730764.1  slimfast, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730764.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VNP7
      Related
      FBpp0078206
      Conserved Domains (2) summary
      TIGR00906
      Location:8 → 557
      2A0303; cationic amino acid transport permease
      pfam13906
      Location:507 → 557
      AA_permease_C; C-terminus of AA_permease
    2. NM_141171.3 → NP_649428.1  slimfast, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649428.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VNP7
      Related
      FBpp0078207
      Conserved Domains (2) summary
      TIGR00906
      Location:8 → 557
      2A0303; cationic amino acid transport permease
      pfam13906
      Location:507 → 557
      AA_permease_C; C-terminus of AA_permease
    3. NM_168978.2 → NP_730765.1  slimfast, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730765.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VNP7
      Related
      FBpp0078208
      Conserved Domains (2) summary
      TIGR00906
      Location:8 → 557
      2A0303; cationic amino acid transport permease
      pfam13906
      Location:507 → 557
      AA_permease_C; C-terminus of AA_permease
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