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    Cap-D3 Chromosome associated protein D3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33778, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cap-D3provided by FlyBase
    Official Full Name
    Chromosome associated protein D3provided by FlyBase
    Primary source
    FLYBASE:FBgn0051989
    Locus tag
    Dmel_CG31989
    See related
    AllianceGenome:FB:FBgn0051989
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE74832; CAP-D2; cap-D3; CAP-D3; CapD3; CG14019; CG31989; CG6922; dCap-D3; dCAP-D3; Dmel\CG31989
    Summary
    Enables chromatin binding activity. Involved in several processes, including chromosome separation; male meiosis chromosome segregation; and regulation of DNA metabolic process. Located in nucleus. Colocalizes with chromosome, centromeric region. Is expressed in organism. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to human NCAPD3 (non-SMC condensin II complex subunit D3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Cap-D3 in Genome Data Viewer
    Location:
    25E5-25E5; 2-17 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5525905..5535958)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5525905..5535958)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene clot Neighboring gene Vacuolar protein sorting 52 Neighboring gene antisense RNA:CR44793 Neighboring gene Elongator complex protein 4 Neighboring gene Cytochrome c oxidase copper chaperone COX11 Neighboring gene uncharacterized protein Neighboring gene Coenzyme Q6 Neighboring gene tombola Neighboring gene uncharacterized protein Neighboring gene Helicase at 25E

    Genomic regions, transcripts, and products

    Bibliography

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables chromatin binding PubMed 
    enables histone binding  
    enables methylated histone binding  
    Component Evidence Code Pubs
    colocalizes_with chromosome, centromeric region PubMed 
    is_active_in condensed chromosome, centromeric region  
    part_of condensin complex  
    part_of condensin complex  
    part_of condensin complex PubMed 
    located_in nucleus PubMed 

    General protein information

    Preferred Names
    chromosome associated protein D3
    Names
    CG31989-PA
    CG31989-PB
    Cap-D3-PA
    Cap-D3-PB
    Chromosome-associated protein D3
    dCAP-D3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      5525905..5535958
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135091.4 → NP_608935.2  chromosome associated protein D3, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608935.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IGJ9, Q9VMQ4
      Related
      FBpp0078730
      Conserved Domains (1) summary
      pfam12717
      Location:889 → 999
      Cnd1; non-SMC mitotic condensation complex subunit 1
    2. NM_001169416.2 → NP_001162887.1  chromosome associated protein D3, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162887.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IGJ9, Q9VMQ4
      Conserved Domains (1) summary
      pfam12717
      Location:889 → 999
      Cnd1; non-SMC mitotic condensation complex subunit 1
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