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    hycD formate hydrogenlyase subunit HycD [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948994, updated on 17-Dec-2024

    Summary

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    Official Symbol
    hycD
    Official Full Name
    formate hydrogenlyase subunit HycD
    Primary source
    ECOCYC:EG10477
    Locus tag
    b2722
    See related
    ASAP:ABE-0008946
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2717; hevD
    Summary
    FhlA regulon. [More information is available at EcoGene: EG10477]. HycD encodes an extremely hydrophobic protein with 8 predicted transmembrane domains. [More information is available at EcoCyc: EG10477].
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    Genomic context

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    Sequence:
    NC_000913.3 (2846489..2847412, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene formate hydrogenlyase subunit HycG Neighboring gene formate hydrogenlyase subunit HycF Neighboring gene formate hydrogenlyase subunit HycE Neighboring gene formate hydrogenlyase subunit HycC Neighboring gene formate hydrogenlyase subunit HycB Neighboring gene regulator of the transcriptional regulator FhlA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Microbial reduction of technetium by Escherichia coli and Desulfovibrio desulfuricans: enhancement via the use of high-activity strains and effect of process parameters. Lloyd JR, et al. Biotechnol Bioeng, 1999. PMID 10567070
    2. Reduction and removal of heptavalent technetium from solution by Escherichia coli. Lloyd JR, et al. J Bacteriol, 1997 Mar. PMID 9068649, Free PMC Article
    3. Regulation of gene expression in fermentative and respiratory systems in Escherichia coli and related bacteria. Lin EC, et al. Annu Rev Genet, 1991. PMID 1812811
    4. Regulated expression in vitro of genes coding for formate hydrogenlyase components of Escherichia coli. Hopper S, et al. J Biol Chem, 1994 Jul 29. PMID 8034728
    5. Global gene expression profiling in Escherichia coli K12: effects of oxygen availability and ArcA. Salmon KA, et al. J Biol Chem, 2005 Apr 15. PMID 15699038

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in anaerobic electron transport chain IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in anaerobic respiration IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in formate oxidation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in glucose catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of formate dehydrogenase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    formate hydrogenlyase subunit HycD
    NP_417202.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2846489..2847412 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417202.1 formate hydrogenlyase subunit HycD [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417202.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FZC4
      Conserved Domains (1) summary
      COG0650
      Location:1 → 306
      HyfC; Formate hydrogenlyase subunit 4 [Energy production and conversion]
    Nucleotide Protein
    Heading Accession and Version

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