gna-1 Glucosamine 6-phosphate N-acetyltransferase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: gna-1
Official Full Name: Glucosamine 6-phosphate N-acetyltransferase
Primary source: WormBase:WBGene00001646
Locus tag: CELE_B0024.12
See related: AllianceGenome:WB:WBGene00001646
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable glucosamine 6-phosphate N-acetyltransferase activity. Predicted to be involved in UDP-N-acetylglucosamine biosynthetic process. Is expressed in nervous system and pharynx. Orthologous to human GNPNAT1 (glucosamine-phosphate N-acetyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See gna-1 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 1

Sequence:: Chromosome: V; NC_003283.11 (10319654..10320151, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Structural and biochemical characterization of a trapped coenzyme A adduct of Caenorhabditis elegans glucosamine-6-phosphate N-acetyltransferase 1
Title: Structural and biochemical characterization of a trapped coenzyme A adduct of Caenorhabditis elegans glucosamine-6-phosphate N-acetyltransferase 1.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

B0024.13 (e-PCR)
- UniSTS:308814

B0024.12 (e-PCR)
- UniSTS:320679

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables acyltransferase activity, transferring groups other than amino-acyl groups	IEA Inferred from Electronic Annotation more info
enables glucosamine 6-phosphate N-acetyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glucosamine 6-phosphate N-acetyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in UDP-N-acetylglucosamine biosynthetic process	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Glucosamine 6-phosphate N-acetyltransferase

NP_505654.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

10319654..10320151 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_073253.7 → NP_505654.1 Glucosamine 6-phosphate N-acetyltransferase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_505654.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q17427

Conserved Domains (1) summary

cl17182
Location:20 → 154

NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate