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    F40A3.3 Phosphatidylethanolamine-binding protein;Phosphatidylethanolamine-binding protein homolog F40A3.3 [ Caenorhabditis elegans ]

    Gene ID: 179168, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F40A3.3
    Official Full Name
    Phosphatidylethanolamine-binding protein;Phosphatidylethanolamine-binding protein homolog F40A3.3
    Primary source
    WormBase:WBGene00018218
    Locus tag
    CELE_F40A3.3
    See related
    AllianceGenome:WB:WBGene00018218
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable lipid binding activity. Located in mitochondrion. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human PEBP1 (phosphatidylethanolamine binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F40A3.3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    4
    Sequence:
    Chromosome: V; NC_003283.11 (7877444..7878514)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Protein nipi-4 Neighboring gene Envelope glycoprotein N Neighboring gene EGF-like domain-containing protein Neighboring gene ncRNA Neighboring gene Conserved secreted protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans. Haynes CM, et al. Mol Cell, 2010 Feb 26. PMID 20188671, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    Phosphatidylethanolamine-binding protein;Phosphatidylethanolamine-binding protein homolog F40A3.3
    NP_001300105.1
    • Confirmed by transcript evidence
    NP_001367640.1
    • Confirmed by transcript evidence
    NP_001379787.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      7877444..7878514
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001380702.2 → NP_001367640.1  Phosphatidylethanolamine-binding protein homolog F40A3.3 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O16264, Q4W526
      Conserved Domains (1) summary
      cd00866
      Location:59 → 206
      PEBP_euk; PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in eukaryotes

    2. NM_001313176.3 → NP_001300105.1  Phosphatidylethanolamine-binding protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3ASH2
      Conserved Domains (1) summary
      cd00866
      Location:64 → 211
      PEBP_euk; PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in eukaryotes

    3. NM_001392552.1 → NP_001379787.1  Phosphatidylethanolamine-binding protein homolog F40A3.3 [Caenorhabditis elegans]

      Status: REVIEWED

      Conserved Domains (1) summary
      cd00866
      Location:23 → 170
      PEBP_euk; PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in eukaryotes
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O16264.1

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