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    SRPRA SRP receptor subunit alpha [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714215, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SRPRAprovided by VGNC
    Official Full Name
    SRP receptor subunit alphaprovided by VGNC
    Primary source
    VGNC:VGNC:77885
    See related
    Ensembl:ENSMMUG00000007938
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    SRPR
    Orthologs
    human mouse all
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    Genomic context

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    See SRPRA in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (119034737..119040762, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (119090300..119096326, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114672434 Neighboring gene RNA pseudouridine synthase D4 Neighboring gene family with sequence similarity 118 member B Neighboring gene FAD dependent oxidoreductase domain containing 1 Neighboring gene small nucleolar RNA U13 Neighboring gene TIR domain containing adaptor protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signal recognition particle binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SRP-dependent cotranslational protein targeting to membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of signal recognition particle receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    signal recognition particle receptor subunit alpha
    Names
    SRP receptor alpha subunit
    signal recognition particle receptor ('docking protein')
    signal recognition particle receptor (docking protein)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266746.1 → NP_001253675.1  signal recognition particle receptor subunit alpha

      See identical proteins and their annotated locations for NP_001253675.1

      Status: PROVISIONAL

      Source sequence(s)
      JV048034
      UniProtKB/TrEMBL
      F6ZRH2, G7NCY4
      Related
      ENSMMUP00000036595.2, ENSMMUT00000043599.3
      Conserved Domains (3) summary
      cd17876
      Location:419 → 635
      SRalpha_C; C-terminal domain of signal recognition particle receptor alpha subunit
      pfam02881
      Location:318 → 389
      SRP54_N; SRP54-type protein, helical bundle domain
      pfam04086
      Location:27 → 298
      SRP-alpha_N; Signal recognition particle, alpha subunit, N-terminal

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      119034737..119040762 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015115912.2 → XP_014971398.1  signal recognition particle receptor subunit alpha isoform X1

      UniProtKB/TrEMBL
      F7HSU8, G7NCY4, I2CXI9
      Related
      ENSMMUP00000010421.3, ENSMMUT00000011113.4
      Conserved Domains (3) summary
      cd17876
      Location:391 → 607
      SRalpha_C; C-terminal domain of signal recognition particle receptor alpha subunit
      pfam02881
      Location:290 → 361
      SRP54_N; SRP54-type protein, helical bundle domain
      pfam04086
      Location:27 → 270
      SRP-alpha_N; Signal recognition particle, alpha subunit, N-terminal
    Nucleotide Protein
    Heading Accession and Version

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