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    GH1 growth hormone 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 718156, updated on 5-Mar-2024

    Summary

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    Gene symbol
    GH1
    Gene description
    growth hormone 1
    See related
    Ensembl:ENSMMUG00000039847
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    GHB3
    Orthologs
    human mouse all
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    Genomic context

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    See GH1 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (60477957..60479664, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (57536876..57538608, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene growth hormone variant Neighboring gene chorionic somatomammotropin-1 Neighboring gene CD79b molecule Neighboring gene sodium voltage-gated channel alpha subunit 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The primary structure of monkey pituitary growth hormone. Li CH, et al. Arch Biochem Biophys, 1986 Feb 15. PMID 3080959
    2. Cloning of four growth hormone/chorionic somatomammotropin-related complementary deoxyribonucleic acids differentially expressed during pregnancy in the rhesus monkey placenta. Golos TG, et al. Endocrinology, 1993 Oct. PMID 8404617
    3. Gene conversions in the growth hormone gene family of primates: stronger homogenizing effects in the Hominidae lineage. Petronella N, et al. Genomics, 2011 Sep. PMID 21683133
    4. Growth hormone-related genes from baboon (Papio hamadryas): Characterization, placental expression and evolutionary aspects. Rodríguez-Sánchez IP, et al. Gene, 2010 Jan 15. PMID 19651193, Free PMC Article
    5. Growth hormone locus expands and diverges after the separation of New and Old World Monkeys. González Alvarez R, et al. Gene, 2006 Sep 15. PMID 16872758

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables growth hormone receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables hormone activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in animal organ development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in growth hormone receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of growth IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of tyrosine phosphorylation of STAT protein IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to nutrient levels IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    somatotropin
    Names
    GH
    GH-N
    growth hormone B3
    pituitary growth hormone

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042738.1 → NP_001036203.1  somatotropin precursor

      See identical proteins and their annotated locations for NP_001036203.1

      Status: PROVISIONAL

      Source sequence(s)
      L16556
      UniProtKB/Swiss-Prot
      P33093
      UniProtKB/TrEMBL
      A0A1D5QZK6, Q1L7V0
      Related
      ENSMMUP00000061131.1, ENSMMUT00000086046.1
      Conserved Domains (1) summary
      cd10285
      Location:35 → 215
      somatotropin_like; Somatotropin or growth hormone (GH), placental lactogen, and related pituitary gland hormones

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      60477957..60479664 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015120066.2 → XP_014975552.1  somatotropin isoform X2

      UniProtKB/TrEMBL
      A0A1D5QZK6
      Conserved Domains (1) summary
      cd10285
      Location:35 → 200
      somatotropin_like; Somatotropin or growth hormone (GH), placental lactogen, and related pituitary gland hormones

    2. XM_015120065.2 → XP_014975551.2  somatotropin isoform X1

      UniProtKB/TrEMBL
      A0A1D5QZK6
      Conserved Domains (1) summary
      cd10285
      Location:35 → 246
      somatotropin_like; Somatotropin or growth hormone (GH), placental lactogen, and related pituitary gland hormones
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P33093.2 GenPept UniProtKB/Swiss-Prot:P33093

    Gene LinkOut

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    Research Materials