U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    CG9674 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39878, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG9674provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036663
    Locus tag
    Dmel_CG9674
    See related
    AllianceGenome:FB:FBgn0036663
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9674; GS
    Summary
    Predicted to enable glutamate synthase (NADH) activity. Predicted to be involved in ammonia assimilation cycle and glutamate biosynthetic process. Is expressed in adult head and spermatozoon. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See CG9674 in Genome Data Viewer
    Location:
    73C4-73D1; 3-44 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (16787573..16807731, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (16780673..16800831, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene eukaryotic translation initiation factor 3 subunit e Neighboring gene nudC Neighboring gene uncharacterized protein Neighboring gene Tumor susceptibility gene 101 Neighboring gene kuduk

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables FMN binding  
    enables flavin adenine dinucleotide binding  
    enables glutamate synthase (NADH) activity  
    enables glutamate synthase (NADH) activity  
    enables glutamate synthase activity  
    enables iron ion binding  
    enables iron-sulfur cluster binding  
    enables oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor  
    Process Evidence Code Pubs
    involved_in ammonia assimilation cycle  
    involved_in glutamate biosynthetic process  
    involved_in glutamate biosynthetic process  

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG9674-PA
    CG9674-PD
    CG9674-PE
    CG9674-PF
    CG9674-PG
    CG9674-PH
    CG9674-PI
    glutamate synthase
    NP_001246803.1
    NP_001246804.1
    NP_001261973.1
    NP_001261974.1
    NP_001287088.1
    NP_648922.1
    NP_788517.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      16787573..16807731 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_176339.2 → NP_788517.1  uncharacterized protein Dmel_CG9674, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788517.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SX95, Q9VVA3, Q9VVA4
      Related
      FBpp0075103
      Conserved Domains (8) summary
      PRK11750
      Location:75 → 1564
      gltB; glutamate synthase subunit alpha; Provisional
      PRK12810
      Location:1622 → 2105
      gltD; glutamate synthase subunit beta; Reviewed
      cd00982
      Location:1315 → 1564
      gltB_C; gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the ...
      cd02808
      Location:917 → 1270
      GltS_FMN; Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast ...
      pfam00310
      Location:88 → 504
      GATase_2; Glutamine amidotransferases class-II
      pfam04898
      Location:542 → 827
      Glu_syn_central; Glutamate synthase central domain
      pfam13450
      Location:1771 → 1803
      NAD_binding_8; NAD(P)-binding Rossmann-like domain
      cl19102
      Location:1644 → 1755
      Fer4_8; 4Fe-4S dicluster domain
    2. NM_001300159.1 → NP_001287088.1  uncharacterized protein Dmel_CG9674, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287088.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PCU8
      Conserved Domains (5) summary
      COG0067
      Location:76 → 456
      GltB1; Glutamate synthase domain 1 [Amino acid transport and metabolism]
      COG0069
      Location:786 → 1164
      GltB2; Glutamate synthase domain 2 [Amino acid transport and metabolism]
      cd02808
      Location:917 → 1164
      GltS_FMN; Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast ...
      pfam00310
      Location:88 → 504
      GATase_2; Glutamine amidotransferases class-II
      pfam04898
      Location:542 → 827
      Glu_syn_central; Glutamate synthase central domain
    3. NM_001275044.1 → NP_001261973.1  uncharacterized protein Dmel_CG9674, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261973.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NFH8
      Conserved Domains (8) summary
      PRK11750
      Location:75 → 1565
      gltB; glutamate synthase subunit alpha; Provisional
      PRK12810
      Location:1623 → 2106
      gltD; glutamate synthase subunit beta; Reviewed
      cd00982
      Location:1316 → 1565
      gltB_C; gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the ...
      cd02808
      Location:918 → 1271
      GltS_FMN; Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast ...
      pfam00310
      Location:88 → 504
      GATase_2; Glutamine amidotransferases class-II
      pfam04898
      Location:543 → 828
      Glu_syn_central; Glutamate synthase central domain
      pfam13450
      Location:1772 → 1804
      NAD_binding_8; NAD(P)-binding Rossmann-like domain
      cl19102
      Location:1645 → 1756
      Fer4_8; 4Fe-4S dicluster domain
    4. NM_001259875.2 → NP_001246804.1  uncharacterized protein Dmel_CG9674, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246804.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NFH8
      Conserved Domains (8) summary
      PRK11750
      Location:75 → 1565
      gltB; glutamate synthase subunit alpha; Provisional
      PRK12810
      Location:1623 → 2106
      gltD; glutamate synthase subunit beta; Reviewed
      cd00982
      Location:1316 → 1565
      gltB_C; gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the ...
      cd02808
      Location:918 → 1271
      GltS_FMN; Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast ...
      pfam00310
      Location:88 → 504
      GATase_2; Glutamine amidotransferases class-II
      pfam04898
      Location:543 → 828
      Glu_syn_central; Glutamate synthase central domain
      pfam13450
      Location:1772 → 1804
      NAD_binding_8; NAD(P)-binding Rossmann-like domain
      cl19102
      Location:1645 → 1756
      Fer4_8; 4Fe-4S dicluster domain
    5. NM_140665.2 → NP_648922.1  uncharacterized protein Dmel_CG9674, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648922.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SX95, Q9VVA3, Q9VVA4
      Related
      FBpp0075100
      Conserved Domains (8) summary
      PRK11750
      Location:75 → 1564
      gltB; glutamate synthase subunit alpha; Provisional
      PRK12810
      Location:1622 → 2105
      gltD; glutamate synthase subunit beta; Reviewed
      cd00982
      Location:1315 → 1564
      gltB_C; gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the ...
      cd02808
      Location:917 → 1270
      GltS_FMN; Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast ...
      pfam00310
      Location:88 → 504
      GATase_2; Glutamine amidotransferases class-II
      pfam04898
      Location:542 → 827
      Glu_syn_central; Glutamate synthase central domain
      pfam13450
      Location:1771 → 1803
      NAD_binding_8; NAD(P)-binding Rossmann-like domain
      cl19102
      Location:1644 → 1755
      Fer4_8; 4Fe-4S dicluster domain
    6. NM_001275045.1 → NP_001261974.1  uncharacterized protein Dmel_CG9674, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261974.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PCU8
      Conserved Domains (5) summary
      COG0067
      Location:76 → 456
      GltB1; Glutamate synthase domain 1 [Amino acid transport and metabolism]
      COG0069
      Location:786 → 1164
      GltB2; Glutamate synthase domain 2 [Amino acid transport and metabolism]
      cd02808
      Location:917 → 1164
      GltS_FMN; Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast ...
      pfam00310
      Location:88 → 504
      GATase_2; Glutamine amidotransferases class-II
      pfam04898
      Location:542 → 827
      Glu_syn_central; Glutamate synthase central domain
    7. NM_001259874.1 → NP_001246803.1  uncharacterized protein Dmel_CG9674, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246803.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PCU8
      Conserved Domains (5) summary
      COG0067
      Location:76 → 456
      GltB1; Glutamate synthase domain 1 [Amino acid transport and metabolism]
      COG0069
      Location:786 → 1164
      GltB2; Glutamate synthase domain 2 [Amino acid transport and metabolism]
      cd02808
      Location:917 → 1164
      GltS_FMN; Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast ...
      pfam00310
      Location:88 → 504
      GATase_2; Glutamine amidotransferases class-II
      pfam04898
      Location:542 → 827
      Glu_syn_central; Glutamate synthase central domain
    External link. Please review our privacy policy.