U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    WD40 domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819354, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Full Name
    WD40 domain-containing protein
    Primary source
    TAIR:AT2G47410
    Locus tag
    AT2G47410
    See related
    Araport:AT2G47410
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T30B22.2
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 2
    Exon count:
    25
    Sequence:
    Chromosome: 2; NC_003071.7 (19448139..19457303)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Prolyl oligopeptidase family protein Neighboring gene ncRNA Neighboring gene CP12 domain-containing protein 1 Neighboring gene Ribosomal RNA adenine dimethylase family protein Neighboring gene Signal transduction histidine kinase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases. Lee JH, et al. Plant Cell, 2008 Jan. PMID 18223036, Free PMC Article
    2. Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes. Zhang Y, et al. Plant Cell, 2008 Jun. PMID 18552200, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    NM_001202841.1
    NM_001337260.1
    NM_001337261.1
    NM_001337262.1
    NM_001337263.1
    NM_180143.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    WD40 domain-containing protein
    NP_001189770.1
    • WD40/YVTN repeat-like-containing domain;Bromodomain; FUNCTIONS IN: nucleotide binding; LOCATED IN: CUL4 RING ubiquitin ligase complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), Bromodomain (InterPro:IPR001487), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: WD40/YVTN repeat-like-containing domain;Bromodomain (TAIR:AT5G49430.1).
    NP_850474.3
    • WD40/YVTN repeat-like-containing domain;Bromodomain; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), Bromodomain (InterPro:IPR001487), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: WD40/YVTN repeat-like-containing domain;Bromodomain (TAIR:AT5G49430.1); Has 67123 Blast hits to 29366 proteins in 847 species: Archae - 50; Bacteria - 8348; Metazoa - 26818; Fungi - 14890; Plants - 8157; Viruses - 8; Other Eukaryotes - 8852 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      19448139..19457303
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001202841.1 → NP_001189770.1  WD40 domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189770.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9X7R9, A0A654F2R3, F4IL44
      Conserved Domains (4) summary
      cd05529
      Location:1389 → 1518
      Bromo_WDR9_I_like; Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
      cd00200
      Location:227 → 598
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      PTZ00108
      Location:764 → 910
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      sd00039
      Location:239 → 275
      7WD40; WD40 repeat [structural motif]

    2. NM_001337262.1 → NP_001324313.1  WD40 domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W3E8, A0A1P8AZQ7, A0A384KA14, A0A654F2R3
      Conserved Domains (5) summary
      cd05529
      Location:1400 → 1529
      Bromo_WDR9_I_like; Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
      cd00200
      Location:228 → 609
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      PTZ00108
      Location:775 → 921
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      sd00039
      Location:239 → 275
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:572 → 656
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. NM_180143.5 → NP_850474.3  WD40 domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850474.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654F2R3, F4IL43
      Conserved Domains (4) summary
      cd05529
      Location:1390 → 1519
      Bromo_WDR9_I_like; Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
      COG2319
      Location:227 → 608
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:228 → 599
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:240 → 276
      7WD40; WD40 repeat [structural motif]

    4. NM_001337260.1 → NP_001324312.1  WD40 domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W2S4, A0A1P8AZS1, A0A384L4J4, A0A654F2R3

    5. NM_001337261.1 → NP_001324314.1  WD40 domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AZR4, A0A654F2R3

    6. NM_001337263.1 → NP_001324315.1  WD40 domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W2S4, A0A1P8AZS1, A0A384L4J4, A0A654F2R3
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools