U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ERF73 Integrase-type DNA-binding superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843568, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ERF73
    Official Full Name
    Integrase-type DNA-binding superfamily protein
    Primary source
    TAIR:AT1G72360
    Locus tag
    AT1G72360
    See related
    Araport:AT1G72360
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtERF73; ethylene response factor 73; HRE1; HYPOXIA RESPONSIVE ERF (ETHYLENE RESPONSE FACTOR) 1; T10D10.17; T10D10_17
    Summary
    Encodes a member of the ERF (ethylene response factor) subfamily B-2 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 5 members in this subfamily including RAP2.2 AND RAP2.12.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ERF73 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (27241696..27242968)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene alanine aminotransferase 2 Neighboring gene NagB/RpiA/CoA transferase-like superfamily protein Neighboring gene MADS-box transcription factor family protein Neighboring gene 40s ribosomal protein SA Neighboring gene nuclear receptor coactivator Neighboring gene COP1-interacting protein-like protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Two Alternative Splicing Variants of AtERF73/HRE1, HRE1α and HRE1β, Have Differential Transactivation Activities in Arabidopsis. Seok HY, et al. Int J Mol Sci, 2020 Sep 23. PMID 32977426, Free PMC Article
    2. ERF73/HRE1 is involved in H(2)O(2) production via hypoxia-inducible Rboh gene expression in hypoxia signaling. Yang CY, et al. Protoplasma, 2017 Jul. PMID 27995331
    3. Arabidopsis HRE1α, a splicing variant of AtERF73/HRE1, functions as a nuclear transcription activator in hypoxia response and root development. Seok HY, et al. Plant Cell Rep, 2014 Aug. PMID 24728113
    4. Ethylene and hydrogen peroxide are involved in hypoxia signaling that modulates AtERF73/HRE1 expression. Yang CY. Plant Signal Behav, 2014. PMID 24698791, Free PMC Article
    5. HRE1 and HRE2, two hypoxia-inducible ethylene response factors, affect anaerobic responses in Arabidopsis thaliana. Licausi F, et al. Plant J, 2010 Apr. PMID 20113439

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Two Alternative Splicing Variants of AtERF73/HRE1, HRE1alpha and HRE1beta, Have Differential Transactivation Activities in Arabidopsis.
      Title: Two Alternative Splicing Variants of AtERF73/HRE1, HRE1α and HRE1β, Have Differential Transactivation Activities in Arabidopsis.
    2. AtERF73/HRE1 plays a role in H2O2 production by affecting the hypoxia-induced expression of Rboh genes in hypoxia signal transduction.
      Title: ERF73/HRE1 is involved in H(2)O(2) production via hypoxia-inducible Rboh gene expression in hypoxia signaling.
    3. AtERF73/HRE1 is involved in modulating ethylene responses under both normoxia and hypoxia.
      Title: The AP2/ERF transcription factor AtERF73/HRE1 modulates ethylene responses during hypoxia in Arabidopsis.
    4. controlled by 3 pathways during hypoxia: an ethylene-dependent pathway, an ethylene-independent/H 2O 2-dependent pathway, and an ethylene and H 2O 2-independent pathway
      Title: Ethylene and hydrogen peroxide are involved in hypoxia signaling that modulates AtERF73/HRE1 expression.
    5. HRE1alpha functions as a transcription activator in the nucleus, and plays an important role in root development through regulation of root meristem cell division.
      Title: Arabidopsis HRE1α, a splicing variant of AtERF73/HRE1, functions as a nuclear transcription activator in hypoxia response and root development.
    6. HRE1 and HRE2 encode two nuclear-localized ethylene response factors specifically up-regulated under low oxygen conditions.
      Title: HRE1 and HRE2, two hypoxia-inducible ethylene response factors, affect anaerobic responses in Arabidopsis thaliana.
    7. rotein localized in the nucleus and functioned as an in vivo transcription activator as confirmed in transient assays and experiments.
      Title: Functional analysis of Arabidopsis ethylene-responsive element binding protein conferring resistance to Bax and abiotic stress-induced plant cell death.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_001084343.2
    NM_001124115.1
    NM_105895.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to anoxia IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to ethylene stimulus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cellular response to ethylene stimulus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to hypoxia IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in cellular response to hypoxia IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ethylene-activated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ethylene-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within ethylene-activated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to anoxia IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within response to ethylene IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to hypoxia IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular anatomical structure TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Integrase-type DNA-binding superfamily protein
    NP_001077812.1
    • HYPOXIA RESPONSIVE ERF (ETHYLENE RESPONSE FACTOR) 1 (HRE1); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: ethylene-responsive element binding protein (TAIR:AT3G16770.1); Has 6097 Blast hits to 5793 proteins in 253 species: Archae - 0; Bacteria - 2; Metazoa - 0; Fungi - 0; Plants - 6054; Viruses - 2; Other Eukaryotes - 39 (source: NCBI BLink).
    NP_001117587.1
    • HYPOXIA RESPONSIVE ERF (ETHYLENE RESPONSE FACTOR) 1 (HRE1); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: ethylene-responsive element binding protein (TAIR:AT3G16770.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_177380.2
    • HYPOXIA RESPONSIVE ERF (ETHYLENE RESPONSE FACTOR) 1 (HRE1); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: Integrase-type DNA-binding superfamily protein (TAIR:AT2G47520.1); Has 6115 Blast hits to 5780 proteins in 251 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 6076; Viruses - 2; Other Eukaryotes - 37 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27241696..27242968
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001084343.2 → NP_001077812.1  Integrase-type DNA-binding superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077812.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IDA7, Q8H0T5, Q9C9D5
      UniProtKB/TrEMBL
      A0A178W8F1
      Conserved Domains (1) summary
      smart00380
      Location:75 → 138
      AP2; DNA-binding domain in plant proteins such as APETALA2 and EREBPs

    2. NM_001124115.1 → NP_001117587.1  Integrase-type DNA-binding superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001117587.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3H5K8
      Conserved Domains (1) summary
      smart00380
      Location:73 → 136
      AP2; DNA-binding domain in plant proteins such as APETALA2 and EREBPs

    3. NM_105895.2 → NP_177380.2  Integrase-type DNA-binding superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177380.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8H0T5
      Conserved Domains (1) summary
      smart00380
      Location:24 → 87
      AP2; DNA-binding domain in plant proteins such as APETALA2 and EREBPs
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8H0T5.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.