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    VDAC5 voltage dependent anion channel 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824154, updated on 18-Sep-2024

    Summary

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    Official Symbol
    VDAC5
    Official Full Name
    voltage dependent anion channel 5
    Primary source
    TAIR:AT3G49920
    Locus tag
    AT3G49920
    See related
    Araport:AT3G49920
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 5; ATVDAC5; F3A4.1; voltage dependent anion channel 5
    Summary
    Encodes a voltage-dependent anion channel (VDAC: AT3G01280/VDAC1, AT5G67500/VDAC2, AT5G15090/VDAC3, AT5G57490/VDAC4, AT5G15090/VDAC5). VDACs are reported to be porin-type, beta-barrel diffusion pores. They are prominently localized in the outer mitochondrial membrane and are involved in metabolite exchange between the organelle and the cytosol.
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    Genomic context

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    See VDAC5 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Sequence:
    Chromosome: 3; NC_003074.8 (18505481..18507835, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Phototropic-responsive NPH3 family protein Neighboring gene ncRNA Neighboring gene Translation protein SH3-like family protein Neighboring gene tRNA-Val Neighboring gene C2H2 and C2HC zinc fingers superfamily protein Neighboring gene LOB domain-containing protein 38

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001203116.2
    NM_114852.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables voltage-gated monoatomic anion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in monoatomic anion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    voltage dependent anion channel 5
    NP_001319718.1
    • voltage dependent anion channel 5 (VDAC5); FUNCTIONS IN: voltage-gated anion channel activity; INVOLVED IN: anion transport, transmembrane transport; LOCATED IN: mitochondrial outer membrane; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: petal differentiation and expansion stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: Porin, eukaryotic type (InterPro:IPR001925); BEST Arabidopsis thaliana protein match is: voltage dependent anion channel 2 (TAIR:AT5G67500.1).
    NP_190561.1
    • voltage dependent anion channel 5 (VDAC5); FUNCTIONS IN: voltage-gated anion channel activity; INVOLVED IN: anion transport, transmembrane transport; LOCATED IN: mitochondrial outer membrane; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: petal differentiation and expansion stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: Porin, eukaryotic type (InterPro:IPR001925); BEST Arabidopsis thaliana protein match is: voltage dependent anion channel 2 (TAIR:AT5G67500.1); Has 294 Blast hits to 290 proteins in 43 species: Archae - 0; Bacteria - 0; Metazoa - 5; Fungi - 6; Plants - 279; Viruses - 0; Other Eukaryotes - 4 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      18505481..18507835 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001339445.1 → NP_001319718.1  voltage dependent anion channel 5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4IZ90

    2. NM_001339446.1 → NP_001325884.1  voltage dependent anion channel 5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LMK6

    3. NM_114852.1 → NP_190561.1  voltage dependent anion channel 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190561.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M2W6
      UniProtKB/TrEMBL
      A0A5S9XK89, A0A654FHM7
      Conserved Domains (1) summary
      cd07306
      Location:5 → 225
      Porin3_VDAC; Voltage-dependent anion channel of the outer mitochondrial membrane

    4. NM_001203116.2 → NP_001190045.1  voltage dependent anion channel 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190045.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4IZ90
      Conserved Domains (1) summary
      cl03224
      Location:5 → 82
      Porin3; Eukaryotic porin family that forms channels in the mitochondrial outer membrane
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M2W6.1

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