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    LSF1 uncharacterized protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821127, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LSF1
    Official Full Name
    uncharacterized protein
    Primary source
    TAIR:AT3G01510
    Locus tag
    AT3G01510
    See related
    Araport:AT3G01510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F4P13.6; F4P13_6; like SEX4 1
    Summary
    Encodes a putative phosphatase, LSF1, required for normal starch turnover in leaves.
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    Genomic context

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    See LSF1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    10
    Sequence:
    Chromosome: 3; NC_003074.8 (198322..201810, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene homeobox 1 Neighboring gene cyclophilin 38 Neighboring gene Protein kinase superfamily protein Neighboring gene carbonic anhydrase 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. LIKE SEX4 1 Acts as a β-Amylase-Binding Scaffold on Starch Granules during Starch Degradation. Schreier TB, et al. Plant Cell, 2019 Sep. PMID 31266901, Free PMC Article
    2. A putative phosphatase, LSF1, is required for normal starch turnover in Arabidopsis leaves. Comparot-Moss S, et al. Plant Physiol, 2010 Feb. PMID 20018601, Free PMC Article
    3. Redox Conformation-Specific Protein-Protein Interactions of the 2-Cysteine Peroxiredoxin in Arabidopsis. Liebthal M, et al. Antioxidants (Basel), 2020 Jun 11. PMID 32545358, Free PMC Article
    4. The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts. Peltier JB, et al. Mol Cell Proteomics, 2006 Jan. PMID 16207701
    5. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A glucan phosphatase family member, LIKE SEX4 1 (LSF1), binds starch and is required for normal starch degradation.
      Title: LIKE SEX4 1 Acts as a β-Amylase-Binding Scaffold on Starch Granules during Starch Degradation.
    2. LSF1 is a chloroplastic protein essential for normal starch degradation.
      Title: A putative phosphatase, LSF1, is required for normal starch turnover in Arabidopsis leaves.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001337343.1
    NM_001337344.1
    NM_111017.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables carbohydrate phosphatase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within starch catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in starch catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast starch grain IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in chloroplast stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in starch grain IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_001325424.1
    • like SEX4 1
    NP_001325425.1
    • like SEX4 1
    NP_566139.1
    • like SEX4 1 (LSF1); FUNCTIONS IN: protein tyrosine/serine/threonine phosphatase activity; INVOLVED IN: starch catabolic process; LOCATED IN: starch grain, chloroplast, chloroplast stroma; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Dual specificity phosphatase, catalytic domain (InterPro:IPR000340), PDZ/DHR/GLGF (InterPro:IPR001478), Dual specificity phosphatase, subgroup, catalytic domain (InterPro:IPR020422); BEST Arabidopsis thaliana protein match is: dual specificity protein phosphatase (DsPTP1) family protein (TAIR:AT3G52180.1); Has 834 Blast hits to 834 proteins in 152 species: Archae - 0; Bacteria - 14; Metazoa - 310; Fungi - 61; Plants - 322; Viruses - 12; Other Eukaryotes - 115 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      198322..201810 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111017.3 → NP_566139.1  uncharacterized protein AT3G01510 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566139.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4J117, Q8LCU3, Q9SSA3
      UniProtKB/TrEMBL
      A0A178V9M4, A0A5S9X969
      Conserved Domains (3) summary
      cd02859
      Location:456 → 536
      E_set_AMPKbeta_like_N; N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain of AMP-activated protein kinase beta subunit
      cd14526
      Location:290 → 435
      DSP_laforin-like; dual specificity phosphatase domain of laforin and similar domains
      cl00117
      Location:76 → 118
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

    2. NM_001337343.1 → NP_001325425.1  uncharacterized protein AT3G01510 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LL73
      Conserved Domains (2) summary
      cd02859
      Location:314 → 394
      E_set_AMPKbeta_like_N; N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain of AMP-activated protein kinase beta subunit
      cd14526
      Location:148 → 293
      DSP_laforin-like; dual specificity phosphatase domain of laforin and similar domains

    3. NM_001337344.1 → NP_001325424.1  uncharacterized protein AT3G01510 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LL73
      Conserved Domains (2) summary
      cd02859
      Location:314 → 394
      E_set_AMPKbeta_like_N; N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain of AMP-activated protein kinase beta subunit
      cd14526
      Location:148 → 293
      DSP_laforin-like; dual specificity phosphatase domain of laforin and similar domains
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4J117.1

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