U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    RUP1 Transducin/WD40 repeat-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835301, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    RUP1
    Official Full Name
    Transducin/WD40 repeat-like superfamily protein
    Primary source
    TAIR:AT5G52250
    Locus tag
    AT5G52250
    See related
    Araport:AT5G52250
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    EARLY FLOWERING BY OVEREXPRESSION 1; EFO1; F17P19.15; F17P19_15; REPRESSOR OF UV-B PHOTOMORPHOGENESIS 1
    Summary
    Encodes a transducin protein whose gene expression is induced by UV-B. This induction is reduced in hy5 mutant and may be a target of HY5 during UV-B response. Functions as a repressor of UV-B signaling.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See RUP1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_003076.8 (21216772..21218351)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene methyl-CPG-binding domain protein 13 Neighboring gene membrane steroid binding protein 1 Neighboring gene myb domain protein 19 Neighboring gene SNARE-like superfamily protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. EFO1 and EFO2, encoding putative WD-domain proteins, have overlapping and distinct roles in the regulation of vegetative development and flowering of Arabidopsis. Wang W, et al. J Exp Bot, 2011 Jan. PMID 21242318
    2. DHU1 negatively regulates UV-B signaling via its direct interaction with COP1 and RUP1. Kim SH, et al. Biochem Biophys Res Commun, 2017 Sep 16. PMID 28735869
    3. Regulation of UVR8 photoreceptor dimer/monomer photo-equilibrium in Arabidopsis plants grown under photoperiodic conditions. Findlay KM, et al. Plant Cell Environ, 2016 Aug. PMID 26864532, Free PMC Article
    4. Two distinct domains of the UVR8 photoreceptor interact with COP1 to initiate UV-B signaling in Arabidopsis. Yin R, et al. Plant Cell, 2015 Jan. PMID 25627067, Free PMC Article
    5. Reversion of the Arabidopsis UV-B photoreceptor UVR8 to the homodimeric ground state. Heijde M, et al. Proc Natl Acad Sci U S A, 2013 Jan 15. PMID 23277547, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. crucial in regulating the UVR8 dimer/monomer photo-equilibrium, promotes reversion to the dimer
      Title: Regulation of UVR8 photoreceptor dimer/monomer photo-equilibrium in Arabidopsis plants grown under photoperiodic conditions.
    2. DHU1 negatively regulates UV-B signaling via its direct interaction with COP1 and RUP1 (At5g52250).
      Title: DHU1 negatively regulates UV-B signaling via its direct interaction with COP1 and RUP1.
    3. EFO1(At5g52250) and EFO2(At5g23730) have overlapping and distinct roles in vegetative development and flowering.
      Title: EFO1 and EFO2, encoding putative WD-domain proteins, have overlapping and distinct roles in the regulation of vegetative development and flowering of Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_124604.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of protein-containing complex assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to UV-B IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to UV-B IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in response to UV-B IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within response to far red light IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to red light IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Transducin/WD40 repeat-like superfamily protein
    NP_200038.1
    • Transducin/WD40 repeat-like superfamily protein; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat (InterPro:IPR001680), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT5G23730.1); Has 19305 Blast hits to 12811 proteins in 562 species: Archae - 16; Bacteria - 3753; Metazoa - 6674; Fungi - 4562; Plants - 2007; Viruses - 0; Other Eukaryotes - 2293 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      21216772..21218351
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124604.5 → NP_200038.1  Transducin/WD40 repeat-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200038.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LBH5, Q9LTJ6
      UniProtKB/TrEMBL
      A0A5S9YDF3, A0A654GA84
      Conserved Domains (2) summary
      sd00039
      Location:74 → 119
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:71 → 381
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LTJ6.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools