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    Zfp609 zinc finger protein 609 [ Mus musculus (house mouse) ]

    Gene ID: 214812, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zfp609provided by MGI
    Official Full Name
    zinc finger protein 609provided by MGI
    Primary source
    MGI:MGI:2674092
    See related
    Ensembl:ENSMUSG00000040524 AllianceGenome:MGI:2674092
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Znf609; mKIAA0295; 9830165N24
    Summary
    Enables promoter-specific chromatin binding activity. Involved in positive regulation of neuron migration; positive regulation of transcription by RNA polymerase II; and regulation of myoblast proliferation. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including brown fat; early conceptus; genitourinary system; gut; and nervous system. Orthologous to human ZNF609 (zinc finger protein 609). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 8.8), CNS E14 (RPKM 8.3) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Zfp609 in Genome Data Viewer
    Location:
    9 C; 9 35.46 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (65598860..65735004, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (65691578..65827564, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_24467 Neighboring gene RNA binding protein with multiple splicing 2 Neighboring gene STARR-positive B cell enhancer ABC_E9768 Neighboring gene STARR-seq mESC enhancer starr_24469 Neighboring gene ornithine decarboxylase antizyme 2 Neighboring gene STARR-seq mESC enhancer starr_24471 Neighboring gene ATP synthase subunit f, mitochondrial-like Neighboring gene thyroid hormone receptor interactor 4 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene predicted gene, 53535

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables promoter-specific chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172536.3NP_766124.2  zinc finger protein 609

      See identical proteins and their annotated locations for NP_766124.2

      Status: VALIDATED

      Source sequence(s)
      AC121979, AK036715, BC016271, BC058943, BF465900
      Consensus CDS
      CCDS23297.2
      UniProtKB/Swiss-Prot
      Q05DD7, Q6PD47, Q6ZQE3, Q8BZ47
      UniProtKB/TrEMBL
      B2RWS7
      Related
      ENSMUSP00000124089.2, ENSMUST00000159109.2
      Conserved Domains (2) summary
      PTZ00449
      Location:10051228
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5189
      Location:412533
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      65598860..65735004 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036154823.1XP_036010716.1  zinc finger protein 609 isoform X3

      UniProtKB/TrEMBL
      B2RWS7
      Conserved Domains (1) summary
      COG5189
      Location:163284
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    2. XM_006511007.5XP_006511070.1  zinc finger protein 609 isoform X2

      UniProtKB/TrEMBL
      B2RWS7
      Conserved Domains (2) summary
      PTZ00449
      Location:776999
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5189
      Location:183304
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    3. XM_036154822.1XP_036010715.1  zinc finger protein 609 isoform X1

      UniProtKB/TrEMBL
      B2RWS7
      Conserved Domains (2) summary
      PTZ00449
      Location:10051228
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5189
      Location:412533
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]