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    Atp6ap1l ATPase, H+ transporting, lysosomal accessory protein 1-like [ Mus musculus (house mouse) ]

    Gene ID: 435376, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Atp6ap1lprovided by MGI
    Official Full Name
    ATPase, H+ transporting, lysosomal accessory protein 1-likeprovided by MGI
    Primary source
    MGI:MGI:3648665
    See related
    Ensembl:ENSMUSG00000078958 AllianceGenome:MGI:3648665
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG435376
    Summary
    Predicted to enable ATPase activator activity. Predicted to be involved in regulation of cellular pH. Predicted to be part of proton-transporting V-type ATPase complex. Orthologous to human ATP6AP1L (ATPase H+ transporting accessory protein 1 like (pseudogene)). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in testis adult (RPKM 39.9), frontal lobe adult (RPKM 6.1) and 1 other tissue See more
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    Genomic context

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    See Atp6ap1l in Genome Data Viewer
    Location:
    13 C3; 13 46.45 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (91031558..91053478, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (90883439..90905355, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 35111 Neighboring gene STARR-seq mESC enhancer starr_35240 Neighboring gene STARR-seq mESC enhancer starr_35241 Neighboring gene STARR-seq mESC enhancer starr_35242 Neighboring gene STARR-seq mESC enhancer starr_35243 Neighboring gene STARR-seq mESC enhancer starr_35244 Neighboring gene crumbs homolog 1 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E3091 Neighboring gene STARR-seq mESC enhancer starr_35246 Neighboring gene ribosomal protein S23 Neighboring gene autophagy related 10 Neighboring gene STARR-seq mESC enhancer starr_35249 Neighboring gene 40S ribosomal protein S14 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The transcriptional landscape of the mammalian genome. Carninci P, et al. Science, 2005 Sep 2. PMID 16141072
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of cellular pH IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of proton-transporting V-type ATPase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    V-type proton ATPase subunit S1-like protein
    Names
    Ac45-related protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145879.1 → NP_001139351.1  V-type proton ATPase subunit S1-like protein precursor

      Status: VALIDATED

      Source sequence(s)
      AC108947, CJ050414, CX238982
      Consensus CDS
      CCDS49325.1
      UniProtKB/TrEMBL
      A0A139ZDP1, D3Z5W0
      Related
      ENSMUSP00000105168.3, ENSMUST00000109541.4
      Conserved Domains (1) summary
      pfam01299
      Location:123 → 277
      Lamp; Lysosome-associated membrane glycoprotein (Lamp)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      91031558..91053478 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006517291.2 → XP_006517354.1  V-type proton ATPase subunit S1-like protein isoform X2

      Conserved Domains (1) summary
      pfam05827
      Location:46 → 186
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

    2. XM_006517290.4 → XP_006517353.1  V-type proton ATPase subunit S1-like protein isoform X1

      UniProtKB/TrEMBL
      A0A139ZDP1
      Conserved Domains (1) summary
      pfam05827
      Location:90 → 230
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

    3. XM_036158087.1 → XP_036013980.1  V-type proton ATPase subunit S1-like protein isoform X3

      Conserved Domains (1) summary
      pfam05827
      Location:34 → 174
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

    4. XM_036158088.1 → XP_036013981.1  V-type proton ATPase subunit S1-like protein isoform X3

      Conserved Domains (1) summary
      pfam05827
      Location:34 → 174
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

    5. XM_017315542.3 → XP_017171031.1  V-type proton ATPase subunit S1-like protein isoform X1

      UniProtKB/TrEMBL
      A0A139ZDP1
      Conserved Domains (1) summary
      pfam05827
      Location:90 → 230
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)
    Nucleotide Protein Strain
    Heading Accession and Version

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