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    Aig1 androgen-induced 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292486, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Aig1provided by RGD
    Official Full Name
    androgen-induced 1provided by RGD
    Primary source
    RGD:1562920
    See related
    EnsemblRapid:ENSRNOG00000010753 AllianceGenome:RGD:1562920
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562920
    Summary
    Predicted to enable hydrolase activity. Predicted to be involved in long-chain fatty acid catabolic process. Predicted to be located in membrane. Predicted to be active in endomembrane system. Orthologous to human AIG1 (androgen induced 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 41.7), Adrenal (RPKM 34.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Aig1 in Genome Data Viewer
    Location:
    1p13
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (9866546..10089454, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (8046430..8269276, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (7816841..8038805, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120098785 Neighboring gene cofilin 1, pseudogene 8 Neighboring gene uncharacterized LOC134484948 Neighboring gene HIVEP zinc finger 2 Neighboring gene ribosomal protein L13A, pseudogene 9 Neighboring gene transfer RNA alanine (anticodon AGC) 27

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs. Parsons WH, et al. Nat Chem Biol, 2016 May. PMID 27018888, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables hydrolase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in long-chain fatty acid catabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    androgen-induced gene 1 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134425.1 → NP_001127897.1  androgen-induced gene 1 protein

      See identical proteins and their annotated locations for NP_001127897.1

      Status: PROVISIONAL

      Source sequence(s)
      BC167098
      UniProtKB/TrEMBL
      A6JP64, B2RZC0
      Related
      ENSRNOP00000039627.3, ENSRNOT00000046539.7
      Conserved Domains (1) summary
      pfam04750
      Location:12 → 219
      Far-17a_AIG1; FAR-17a/AIG1-like protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      9866546..10089454 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039103611.2 → XP_038959539.1  androgen-induced gene 1 protein isoform X4

      Conserved Domains (1) summary
      pfam04750
      Location:12 → 185
      Far-17a_AIG1; FAR-17a/AIG1-like protein

    2. XM_039103617.2 → XP_038959545.1  androgen-induced gene 1 protein isoform X5

      UniProtKB/TrEMBL
      A0A8I5ZRM1, A0A8I5ZTN0
      Conserved Domains (1) summary
      pfam04750
      Location:12 → 133
      Far-17a_AIG1; FAR-17a/AIG1-like protein

    3. XM_039103609.2 → XP_038959537.1  androgen-induced gene 1 protein isoform X2

      UniProtKB/TrEMBL
      A6JP64
      Conserved Domains (1) summary
      pfam04750
      Location:12 → 185
      Far-17a_AIG1; FAR-17a/AIG1-like protein

    4. XM_039103610.2 → XP_038959538.1  androgen-induced gene 1 protein isoform X3

      Conserved Domains (1) summary
      pfam04750
      Location:12 → 133
      Far-17a_AIG1; FAR-17a/AIG1-like protein

    5. XM_006227642.5 → XP_006227704.1  androgen-induced gene 1 protein isoform X1

      UniProtKB/TrEMBL
      A0A8I6ABV0, A6JP64
      Related
      ENSRNOP00000091332.1, ENSRNOT00000114127.2
      Conserved Domains (1) summary
      pfam04750
      Location:12 → 219
      Far-17a_AIG1; FAR-17a/AIG1-like protein

    6. XM_039103626.2 → XP_038959554.1  androgen-induced gene 1 protein isoform X7

    7. XM_008758604.4 → XP_008756826.1  androgen-induced gene 1 protein isoform X9

      Conserved Domains (1) summary
      pfam04750
      Location:12 → 133
      Far-17a_AIG1; FAR-17a/AIG1-like protein

    8. XM_039103624.2 → XP_038959552.1  androgen-induced gene 1 protein isoform X6

      Conserved Domains (1) summary
      pfam04750
      Location:12 → 133
      Far-17a_AIG1; FAR-17a/AIG1-like protein

    9. XM_039103631.2 → XP_038959559.1  androgen-induced gene 1 protein isoform X8

      Conserved Domains (1) summary
      pfam04750
      Location:12 → 133
      Far-17a_AIG1; FAR-17a/AIG1-like protein

    RNA

    1. XR_005500901.2 RNA Sequence

    2. XR_010064540.1 RNA Sequence

    3. XR_010064541.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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