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Conserved domains on  [gi|672033760|ref|XP_008756826|]
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androgen-induced gene 1 protein isoform X9 [Rattus norvegicus]

Protein Classification

androgen-induced gene 1 family protein( domain architecture ID 5562)

androgen-induced gene 1 (AIG1) family protein hydrolyzes bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), but not other major classes of lipids

Gene Ontology:  GO:0016020
PubMed:  11266118|27018888

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Far-17a_AIG1 super family cl04723
FAR-17a/AIG1-like protein; This family includes the hamster androgen-induced FAR-17a protein, ...
 12-133 5.23e-43

FAR-17a/AIG1-like protein; This family includes the hamster androgen-induced FAR-17a protein, and its human homolog, the AIG1 protein. The function of these proteins is unknown. This family also includes homologous regions from a number of other metazoan proteins.


The actual alignment was detected with superfamily member pfam04750:

Pssm-ID: 428104  Cd Length: 206  Bit Score: 140.54  E-value: 5.23e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672033760   12 AILLSYCSILCNYKAIEMPSHQ-------TYGGSWKFLTFIDLVIQAVFFGICVLTDLSslltrgsgnQEQERQLRKLIS 84
Cdd:pfam04750   1 FRLLFHLSVLCWYAALFYYFHQyprlpnrHYGGKFKYLTFINLVLQAVFFGLAVLADFS---------TEQLRKLRKLHK 71

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 672033760   85 LRDWTLAVLAFPVGVFVVAVFWTIYAYDREMIYPRLLDNFIPGWLNHGM 133
Cdd:pfam04750  72 LRDFLFAVLAFPVGVFVSVLFWGLYLIDPELVYPKLLDEIIPSWLNHGM 120
 
Name Accession Description Interval E-value
Far-17a_AIG1 pfam04750
FAR-17a/AIG1-like protein; This family includes the hamster androgen-induced FAR-17a protein, ...
 12-133 5.23e-43

FAR-17a/AIG1-like protein; This family includes the hamster androgen-induced FAR-17a protein, and its human homolog, the AIG1 protein. The function of these proteins is unknown. This family also includes homologous regions from a number of other metazoan proteins.


Pssm-ID: 428104  Cd Length: 206  Bit Score: 140.54  E-value: 5.23e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672033760   12 AILLSYCSILCNYKAIEMPSHQ-------TYGGSWKFLTFIDLVIQAVFFGICVLTDLSslltrgsgnQEQERQLRKLIS 84
Cdd:pfam04750   1 FRLLFHLSVLCWYAALFYYFHQyprlpnrHYGGKFKYLTFINLVLQAVFFGLAVLADFS---------TEQLRKLRKLHK 71

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 672033760   85 LRDWTLAVLAFPVGVFVVAVFWTIYAYDREMIYPRLLDNFIPGWLNHGM 133
Cdd:pfam04750  72 LRDFLFAVLAFPVGVFVSVLFWGLYLIDPELVYPKLLDEIIPSWLNHGM 120
 
Name Accession Description Interval E-value
Far-17a_AIG1 pfam04750
FAR-17a/AIG1-like protein; This family includes the hamster androgen-induced FAR-17a protein, ...
 12-133 5.23e-43

FAR-17a/AIG1-like protein; This family includes the hamster androgen-induced FAR-17a protein, and its human homolog, the AIG1 protein. The function of these proteins is unknown. This family also includes homologous regions from a number of other metazoan proteins.


Pssm-ID: 428104  Cd Length: 206  Bit Score: 140.54  E-value: 5.23e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672033760   12 AILLSYCSILCNYKAIEMPSHQ-------TYGGSWKFLTFIDLVIQAVFFGICVLTDLSslltrgsgnQEQERQLRKLIS 84
Cdd:pfam04750   1 FRLLFHLSVLCWYAALFYYFHQyprlpnrHYGGKFKYLTFINLVLQAVFFGLAVLADFS---------TEQLRKLRKLHK 71

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 672033760   85 LRDWTLAVLAFPVGVFVVAVFWTIYAYDREMIYPRLLDNFIPGWLNHGM 133
Cdd:pfam04750  72 LRDFLFAVLAFPVGVFVSVLFWGLYLIDPELVYPKLLDEIIPSWLNHGM 120
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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