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    MSI2 Transducin family protein / WD-40 repeat family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816179, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MSI2
    Official Full Name
    Transducin family protein / WD-40 repeat family protein
    Primary source
    TAIR:AT2G16780
    Locus tag
    AT2G16780
    See related
    Araport:AT2G16780
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MSI02; MULTICOPY SUPPRESSOR OF IRA1 2; NFC02; NFC2; NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP C 2; T24I21.19; T24I21_19
    Summary
    Encodes a WD-40 repeat protein similar to yeast MSI1.
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    Genomic context

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    See MSI2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (7281374..7283686, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene kinase with adenine nucleotide alpha hydrolases-like domain-containing protein Neighboring gene Calcium-dependent phosphotriesterase superfamily protein Neighboring gene Basic-leucine zipper (bZIP) transcription factor family protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene high-affinity nickel-transport family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases. Lee JH, et al. Plant Cell, 2008 Jan. PMID 18223036, Free PMC Article
    2. Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes. Zhang Y, et al. Plant Cell, 2008 Jun. PMID 18552200, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_127230.4

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Transducin family protein / WD-40 repeat family protein
    NP_179269.1
    • MULTICOPY SUPPRESSOR OF IRA1 2 (MSI2); CONTAINS InterPro DOMAIN/s: Histone-binding protein RBBP4 (InterPro:IPR022052), WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin family protein / WD-40 repeat family protein (TAIR:AT4G35050.1); Has 43623 Blast hits to 25846 proteins in 733 species: Archae - 34; Bacteria - 4140; Metazoa - 17646; Fungi - 10305; Plants - 5712; Viruses - 0; Other Eukaryotes - 5786 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      7281374..7283686 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127230.4 → NP_179269.1  Transducin family protein / WD-40 repeat family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179269.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22468
      UniProtKB/TrEMBL
      A0A178VUH5, A0A7G2EB44
      Conserved Domains (3) summary
      COG2319
      Location:164 → 397
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:120 → 166
      7WD40; WD40 repeat [structural motif]
      pfam12265
      Location:16 → 88
      CAF1C_H4-bd; Histone-binding protein RBBP4 or subunit C of CAF1 complex
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22468.1

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