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    Disease resistance protein (TIR-NBS-LRR class) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830995, updated on 18-Sep-2024

    Summary

    Official Full Name
    Disease resistance protein (TIR-NBS-LRR class)
    Primary source
    TAIR:AT5G11250
    Locus tag
    AT5G11250
    See related
    Araport:AT5G11250
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F2I11.140; F2I11_140
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    Genomic context

    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (3587978..3593271, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene transducin family protein / WD-40 repeat family protein Neighboring gene miscRNA Neighboring gene Basic-leucine zipper (bZIP) transcription factor family protein Neighboring gene overexpressor of cationic peroxidase 3 Neighboring gene tail fiber

    General gene information

    NM_001343173.1
    NM_001343174.1
    NM_121163.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within regulation of cellular response to stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    Disease resistance protein (TIR-NBS-LRR class)
    NP_001318538.1
    • Disease resistance protein (TIR-NBS-LRR class); FUNCTIONS IN: transmembrane receptor activity, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane, chloroplast; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT2G14080.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      3587978..3593271 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343173.1NP_001318538.1  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UIN0, A0A1P8BFM2
    2. NM_001343174.1NP_001332026.1  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UIN0, A0A1P8BFM2
    3. NM_121163.2NP_196686.1  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196686.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UIN0, A0A654G0B9, Q9LFN1
      Conserved Domains (2) summary
      PLN03210
      Location:581186
      PLN03210; Resistant to P. syringae 6; Provisional
      sd00033
      Location:678700
      LRR_RI; leucine-rich repeat [structural motif]