|
Name |
Accession |
Description |
Interval |
E-value |
| PLN03210 |
PLN03210 |
Resistant to P. syringae 6; Provisional |
58-1186 |
0e+00 |
|
Resistant to P. syringae 6; Provisional
Pssm-ID: 215633 [Multi-domain] Cd Length: 1153 Bit Score: 859.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 58 CIWTHQVFPSFSGEDVRRDFLSHIQMEFQRMGITPFVDNEIKRGESIGPELLRAIRGSKIAIILLSRNYASSKWCLDELV 137
Cdd:PLN03210 9 RNWVYDVFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEIERSQSLDPELKQAIRDSRIAVVVFSKNYASSSWCLNELL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 138 EIMKCREEYGQTVMAIFYKVDPSDVKNLTGDFGKVFRKTCAGKPKKDIGRWRQAWEKVATVAGYHSINWDNEAAMIKKIA 217
Cdd:PLN03210 89 EIVRCKEELGQLVIPVFYGLDPSHVRKQTGDFGEAFEKTCQNKTEDEKIQWKQALTDVANILGYHSQNWPNEAKMIEEIA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 218 TDISNILiNSTPSRDFDGLVGMRAHLEKMKPLLCLDTDEVRIIGIWGPPGIGKTTIARVVYNQLSHSFQLSVFMENI--- 294
Cdd:PLN03210 169 NDVLGKL-NLTPSNDFEDFVGIEDHIAKMSSLLHLESEEVRMVGIWGSSGIGKTTIARALFSRLSRQFQSSVFIDRAfis 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 295 --KANYTRpTGSDDYSAKLQLQQMFMSQITKQKDIEIPHLGVAQDRLKDKKVLVVLDGVNQSVQLDAMAKEAWWFGPGSR 372
Cdd:PLN03210 248 ksMEIYSS-ANPDDYNMKLHLQRAFLSEILDKKDIKIYHLGAMEERLKHRKVLIFIDDLDDQDVLDALAGQTQWFGSGSR 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 373 IIITTQDQKLFRAHGINHIYKVDFPPTEEALQIFCMYAFGQNSPKDGFQNLAWKVINLAGNLPLGLRIMGSYFRGMSREE 452
Cdd:PLN03210 327 IIVITKDKHFLRAHGIDHIYEVCLPSNELALEMFCRSAFKKNSPPDGFMELASEVALRAGNLPLGLNVLGSYLRGRDKED 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 453 WKKSLPRLESSLDADIQSILKFSYDALDD-EDKNLFLHIACFFNGKEIKILEEHLAKKFVEVRQRLNVLAEKSLIsFSNW 531
Cdd:PLN03210 407 WMDMLPRLRNGLDGKIEKTLRVSYDGLNNkKDKAIFRHIACLFNGEKVNDIKLLLANSDLDVNIGLKNLVDKSLI-HVRE 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 532 GTIEMHKLLAKLGGEIVRNQSiHEPGQRQFLFDGEEICDVLNgDAAGSKSVIGIDFHYIIEEEFDMNERVFEGMSNLQFL 611
Cdd:PLN03210 486 DIVEMHSLLQEMGKEIVRAQS-NEPGEREFLVDAKDICDVLE-DNTGTKKVLGITLDIDEIDELHIHENAFKGMRNLLFL 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 612 RF-----DCDHD-TLQLSRGLSYLSRKLQLLDWIYFPMTCLPSTVNVEFLIELNLTHSKLDMLWEGVKPLHNLRQMDLSY 685
Cdd:PLN03210 564 KFytkkwDQKKEvRWHLPEGFDYLPPKLRLLRWDKYPLRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRG 643
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 686 SVNLKELPDLSTAINLRKLILSNCSSLIKLPSCIGNAINLEDLDLNGCSSLVELPSfgdAINLQKLllrYCsnlvelpss 765
Cdd:PLN03210 644 SKNLKEIPDLSMATNLETLKLSDCSSLVELPSSIQYLNKLEDLDMSRCENLEILPT---GINLKSL---YR--------- 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 766 ignainlreLDLYYCSSLIRLPsSIGNAINLLILDLNGcsnLLELPSSignaINLQKLDLRRcakLLELPSSignaiNLQ 845
Cdd:PLN03210 709 ---------LNLSGCSRLKSFP-DISTNISWLDLDETA---IEEFPSN----LRLENLDELI---LCEMKSE-----KLW 763
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 846 NLLLDDCSSLLELPSSignatnLVYMNLSNCSNLVELPLSIGNLQKLQELILKGCSKLEDLPININLESLDILVLNDCSM 925
Cdd:PLN03210 764 ERVQPLTPLMTMLSPS------LTRLFLSDIPSLVELPSSIQNLHKLEHLEIENCINLETLPTGINLESLESLDLSGCSR 837
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 926 LKRFPEISTNVRALYLCGTAIEEVPLSIRSWPRLDELLMSYFDNLvefphvldiitnldlsgkeiQEVPPlikRISRLQT 1005
Cdd:PLN03210 838 LRTFPDISTNISDLNLSRTGIEEVPWWIEKFSNLSFLDMNGCNNL--------------------QRVSL---NISKLKH 894
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 1006 LILKGYRKVVSLPQIpdslKWIDAEDCESLERLDCSFHNPE-ITLFFGKCFKLNQEARdLIIQTPTKQAVLPGREVPAYF 1084
Cdd:PLN03210 895 LETVDFSDCGALTEA----SWNGSPSEVAMATDNIHSKLPStVCINFINCFNLDQEAL-LQQQSIFKQLILSGEEVPSYF 969
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 1085 THRASGGSLTI--KLNERPLPTSMRYKACILLvrigdygahDRDKWLHVAFGVR---------------STTLGHIIYSG 1147
Cdd:PLN03210 970 THRTTGASLTNipLLHISPCQPFFRFRACAVV---------DSESFFIISVSFDiqvccrfidrlgnhfDSPYQPHVFSV 1040
|
1130 1140 1150 1160 1170
....*....|....*....|....*....|....*....|....*....|..
gi 15238999 1148 LTE--HLYTFEI-----EEKVTSSELVF-----EFKVENGN-HWKIGECGLR 1186
Cdd:PLN03210 1041 TKKgsHLVIFDCcfplnEDNAPLAELNYdhvdiQFRLTNKNsQLKLKGCGIR 1092
|
|
| TIR |
pfam01582 |
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
62-222 |
2.83e-60 |
|
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.
Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 203.75 E-value: 2.83e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 62 HQVFPSFSGEDVRRDFLSHIQMEFQRMGITPFVD-NEIKRGESIGPELLRAIRGSKIAIILLSRNYASSKWCLDELVEIM 140
Cdd:pfam01582 1 YDVFLSFRGSDTREWFVSHLLKELKQKGIKLFIDdRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDELVKIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 141 KCREEYGQTVMAIFYKVDPSDVKNLTGDFGKVFRKTCAGKPKKDIGRWRQAWEKVATVagYHSINWDNEAAMIKKIATDI 220
Cdd:pfam01582 81 ECALDLGQKVIPIFYEVDPSDVRKQTGSFGKAFKKHKKVLTEEKVLKWRGALNEVANI--WHSKSVSDESKFWKKIAYDI 158
|
..
gi 15238999 221 SN 222
Cdd:pfam01582 159 SN 160
|
|
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
61-191 |
4.25e-38 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 139.38 E-value: 4.25e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 61 THQVFPSFSG-EDVRRDFLSHIQMEFQRMGITPFVDNEIkRGESIGPELLRAIRGSKIAIILLSRNYASSKWCLDELVEI 139
Cdd:smart00255 1 EYDVFISYSGkEDVRNEFLSHLLEKLRGYGLCVFIDDFE-PGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVAA 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 15238999 140 MKCREEYGQ-TVMAIFYKVDPSDVKNLTGDFGKVFRKTCAGKPKKDIGR-WRQA 191
Cdd:smart00255 80 LENALEEGGlRVIPIFYEVIPSDVRKQPGKFRKVFKKNYLKWPEDEKEQfWKKA 133
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
655-1036 |
3.45e-22 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 100.78 E-value: 3.45e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 655 LIELNLTHSKLDMLWEGVKPLHNLRQMDLSYSVNLKELPDLSTAINLRKLILSNCSsLIKLPSCIGNAINLEDLDLNGCS 734
Cdd:COG4886 69 LSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQ-LTDLPEELANLTNLKELDLSNNQ 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 735 sLVELPS-FGDAINLQKLLLRYCsNLVELPSSIGNAINLRELDLYYCsSLIRLPSSIGNAINLLILDLNGCsNLLELPSS 813
Cdd:COG4886 148 -LTDLPEpLGNLTNLKSLDLSNN-QLTDLPEELGNLTNLKELDLSNN-QITDLPEPLGNLTNLEELDLSGN-QLTDLPEP 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 814 IGNAINLQKLDLRRCaKLLELPssignainlqnlllddcssllelpsSIGNATNLVYMNLSNCsNLVELPlSIGNLQKLQ 893
Cdd:COG4886 224 LANLTNLETLDLSNN-QLTDLP-------------------------ELGNLTNLEELDLSNN-QLTDLP-PLANLTNLK 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 894 ELILKGCsKLEDLpiniNLESLD-ILVLNDCSMLKRFPEISTNVRALYLCGTAIEEVPLSIRSWPRLDELLMSYFDNLVE 972
Cdd:COG4886 276 TLDLSNN-QLTDL----KLKELElLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALL 350
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15238999 973 FPHVLDIITNLDLSGKEIQEVPPLIKRISRLQTLILKGYRKVVSLPQIPDSLKWIDAEDCESLE 1036
Cdd:COG4886 351 TLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
|
|
| AMN1 |
cd09293 |
Antagonist of mitotic exit network protein 1; Amn1 has been functionally characterized in ... |
757-932 |
1.72e-03 |
|
Antagonist of mitotic exit network protein 1; Amn1 has been functionally characterized in Saccharomyces cerevisiae as a component of the Antagonist of MEN pathway (AMEN). The AMEN network is activated by MEN (mitotic exit network) via an active Cdc14, and in turn switches off MEN. Amn1 constitutes one of the alternative mechanisms by which MEN may be disrupted. Specifically, Amn1 binds Tem1 (Termination of M-phase, a GTPase that belongs to the RAS superfamily), and disrupts its association with Cdc15, the primary downstream target. Amn1 is a leucine-rich repeat (LRR) protein, with 12 repeats in the S. cerevisiae ortholog. As a negative regulator of the signal transduction pathway MEN, overexpression of AMN1 slows the growth of wild type cells. The function of the vertebrate members of this family has not been determined experimentally, they have fewer LRRs that determine the extent of this model.
Pssm-ID: 187754 [Multi-domain] Cd Length: 226 Bit Score: 41.16 E-value: 1.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 757 SNLVELPSSIGNaiNLRELDLYYCSSLIRLPSSIGNAINLLILDLNGCSN-----LLELPSSIGnaiNLQKLDLRRCAKL 831
Cdd:cd09293 17 SNISQLLRILHS--GLEWLELYMCPISDPPLDQLSNCNKLKKLILPGSKLiddegLIALAQSCP---NLQVLDLRACENI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 832 lelpSSIG-----------NAINLQNLLLDDCSSLLELPSSIGNATNLVYMNLSNC--SNLVELPLSIGNLQKLQELILK 898
Cdd:cd09293 92 ----TDSGivalatncpklQTINLGRHRNGHLITDVSLSALGKNCTFLQTVGFAGCdvTDKGVWELASGCSKSLERLSLN 167
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 15238999 899 GCSKLEDLPININLES-----LDILVLNDCSMLKRF-PEI 932
Cdd:cd09293 168 NCRNLTDQSIPAILASnyfpnLSVLEFRGCPLITDFsRII 207
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN03210 |
PLN03210 |
Resistant to P. syringae 6; Provisional |
58-1186 |
0e+00 |
|
Resistant to P. syringae 6; Provisional
Pssm-ID: 215633 [Multi-domain] Cd Length: 1153 Bit Score: 859.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 58 CIWTHQVFPSFSGEDVRRDFLSHIQMEFQRMGITPFVDNEIKRGESIGPELLRAIRGSKIAIILLSRNYASSKWCLDELV 137
Cdd:PLN03210 9 RNWVYDVFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEIERSQSLDPELKQAIRDSRIAVVVFSKNYASSSWCLNELL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 138 EIMKCREEYGQTVMAIFYKVDPSDVKNLTGDFGKVFRKTCAGKPKKDIGRWRQAWEKVATVAGYHSINWDNEAAMIKKIA 217
Cdd:PLN03210 89 EIVRCKEELGQLVIPVFYGLDPSHVRKQTGDFGEAFEKTCQNKTEDEKIQWKQALTDVANILGYHSQNWPNEAKMIEEIA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 218 TDISNILiNSTPSRDFDGLVGMRAHLEKMKPLLCLDTDEVRIIGIWGPPGIGKTTIARVVYNQLSHSFQLSVFMENI--- 294
Cdd:PLN03210 169 NDVLGKL-NLTPSNDFEDFVGIEDHIAKMSSLLHLESEEVRMVGIWGSSGIGKTTIARALFSRLSRQFQSSVFIDRAfis 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 295 --KANYTRpTGSDDYSAKLQLQQMFMSQITKQKDIEIPHLGVAQDRLKDKKVLVVLDGVNQSVQLDAMAKEAWWFGPGSR 372
Cdd:PLN03210 248 ksMEIYSS-ANPDDYNMKLHLQRAFLSEILDKKDIKIYHLGAMEERLKHRKVLIFIDDLDDQDVLDALAGQTQWFGSGSR 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 373 IIITTQDQKLFRAHGINHIYKVDFPPTEEALQIFCMYAFGQNSPKDGFQNLAWKVINLAGNLPLGLRIMGSYFRGMSREE 452
Cdd:PLN03210 327 IIVITKDKHFLRAHGIDHIYEVCLPSNELALEMFCRSAFKKNSPPDGFMELASEVALRAGNLPLGLNVLGSYLRGRDKED 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 453 WKKSLPRLESSLDADIQSILKFSYDALDD-EDKNLFLHIACFFNGKEIKILEEHLAKKFVEVRQRLNVLAEKSLIsFSNW 531
Cdd:PLN03210 407 WMDMLPRLRNGLDGKIEKTLRVSYDGLNNkKDKAIFRHIACLFNGEKVNDIKLLLANSDLDVNIGLKNLVDKSLI-HVRE 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 532 GTIEMHKLLAKLGGEIVRNQSiHEPGQRQFLFDGEEICDVLNgDAAGSKSVIGIDFHYIIEEEFDMNERVFEGMSNLQFL 611
Cdd:PLN03210 486 DIVEMHSLLQEMGKEIVRAQS-NEPGEREFLVDAKDICDVLE-DNTGTKKVLGITLDIDEIDELHIHENAFKGMRNLLFL 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 612 RF-----DCDHD-TLQLSRGLSYLSRKLQLLDWIYFPMTCLPSTVNVEFLIELNLTHSKLDMLWEGVKPLHNLRQMDLSY 685
Cdd:PLN03210 564 KFytkkwDQKKEvRWHLPEGFDYLPPKLRLLRWDKYPLRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRG 643
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 686 SVNLKELPDLSTAINLRKLILSNCSSLIKLPSCIGNAINLEDLDLNGCSSLVELPSfgdAINLQKLllrYCsnlvelpss 765
Cdd:PLN03210 644 SKNLKEIPDLSMATNLETLKLSDCSSLVELPSSIQYLNKLEDLDMSRCENLEILPT---GINLKSL---YR--------- 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 766 ignainlreLDLYYCSSLIRLPsSIGNAINLLILDLNGcsnLLELPSSignaINLQKLDLRRcakLLELPSSignaiNLQ 845
Cdd:PLN03210 709 ---------LNLSGCSRLKSFP-DISTNISWLDLDETA---IEEFPSN----LRLENLDELI---LCEMKSE-----KLW 763
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 846 NLLLDDCSSLLELPSSignatnLVYMNLSNCSNLVELPLSIGNLQKLQELILKGCSKLEDLPININLESLDILVLNDCSM 925
Cdd:PLN03210 764 ERVQPLTPLMTMLSPS------LTRLFLSDIPSLVELPSSIQNLHKLEHLEIENCINLETLPTGINLESLESLDLSGCSR 837
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 926 LKRFPEISTNVRALYLCGTAIEEVPLSIRSWPRLDELLMSYFDNLvefphvldiitnldlsgkeiQEVPPlikRISRLQT 1005
Cdd:PLN03210 838 LRTFPDISTNISDLNLSRTGIEEVPWWIEKFSNLSFLDMNGCNNL--------------------QRVSL---NISKLKH 894
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 1006 LILKGYRKVVSLPQIpdslKWIDAEDCESLERLDCSFHNPE-ITLFFGKCFKLNQEARdLIIQTPTKQAVLPGREVPAYF 1084
Cdd:PLN03210 895 LETVDFSDCGALTEA----SWNGSPSEVAMATDNIHSKLPStVCINFINCFNLDQEAL-LQQQSIFKQLILSGEEVPSYF 969
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 1085 THRASGGSLTI--KLNERPLPTSMRYKACILLvrigdygahDRDKWLHVAFGVR---------------STTLGHIIYSG 1147
Cdd:PLN03210 970 THRTTGASLTNipLLHISPCQPFFRFRACAVV---------DSESFFIISVSFDiqvccrfidrlgnhfDSPYQPHVFSV 1040
|
1130 1140 1150 1160 1170
....*....|....*....|....*....|....*....|....*....|..
gi 15238999 1148 LTE--HLYTFEI-----EEKVTSSELVF-----EFKVENGN-HWKIGECGLR 1186
Cdd:PLN03210 1041 TKKgsHLVIFDCcfplnEDNAPLAELNYdhvdiQFRLTNKNsQLKLKGCGIR 1092
|
|
| TIR |
pfam01582 |
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
62-222 |
2.83e-60 |
|
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.
Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 203.75 E-value: 2.83e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 62 HQVFPSFSGEDVRRDFLSHIQMEFQRMGITPFVD-NEIKRGESIGPELLRAIRGSKIAIILLSRNYASSKWCLDELVEIM 140
Cdd:pfam01582 1 YDVFLSFRGSDTREWFVSHLLKELKQKGIKLFIDdRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDELVKIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 141 KCREEYGQTVMAIFYKVDPSDVKNLTGDFGKVFRKTCAGKPKKDIGRWRQAWEKVATVagYHSINWDNEAAMIKKIATDI 220
Cdd:pfam01582 81 ECALDLGQKVIPIFYEVDPSDVRKQTGSFGKAFKKHKKVLTEEKVLKWRGALNEVANI--WHSKSVSDESKFWKKIAYDI 158
|
..
gi 15238999 221 SN 222
Cdd:pfam01582 159 SN 160
|
|
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
61-191 |
4.25e-38 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 139.38 E-value: 4.25e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 61 THQVFPSFSG-EDVRRDFLSHIQMEFQRMGITPFVDNEIkRGESIGPELLRAIRGSKIAIILLSRNYASSKWCLDELVEI 139
Cdd:smart00255 1 EYDVFISYSGkEDVRNEFLSHLLEKLRGYGLCVFIDDFE-PGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVAA 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 15238999 140 MKCREEYGQ-TVMAIFYKVDPSDVKNLTGDFGKVFRKTCAGKPKKDIGR-WRQA 191
Cdd:smart00255 80 LENALEEGGlRVIPIFYEVIPSDVRKQPGKFRKVFKKNYLKWPEDEKEQfWKKA 133
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
655-1036 |
3.45e-22 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 100.78 E-value: 3.45e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 655 LIELNLTHSKLDMLWEGVKPLHNLRQMDLSYSVNLKELPDLSTAINLRKLILSNCSsLIKLPSCIGNAINLEDLDLNGCS 734
Cdd:COG4886 69 LSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQ-LTDLPEELANLTNLKELDLSNNQ 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 735 sLVELPS-FGDAINLQKLLLRYCsNLVELPSSIGNAINLRELDLYYCsSLIRLPSSIGNAINLLILDLNGCsNLLELPSS 813
Cdd:COG4886 148 -LTDLPEpLGNLTNLKSLDLSNN-QLTDLPEELGNLTNLKELDLSNN-QITDLPEPLGNLTNLEELDLSGN-QLTDLPEP 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 814 IGNAINLQKLDLRRCaKLLELPssignainlqnlllddcssllelpsSIGNATNLVYMNLSNCsNLVELPlSIGNLQKLQ 893
Cdd:COG4886 224 LANLTNLETLDLSNN-QLTDLP-------------------------ELGNLTNLEELDLSNN-QLTDLP-PLANLTNLK 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 894 ELILKGCsKLEDLpiniNLESLD-ILVLNDCSMLKRFPEISTNVRALYLCGTAIEEVPLSIRSWPRLDELLMSYFDNLVE 972
Cdd:COG4886 276 TLDLSNN-QLTDL----KLKELElLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALL 350
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15238999 973 FPHVLDIITNLDLSGKEIQEVPPLIKRISRLQTLILKGYRKVVSLPQIPDSLKWIDAEDCESLE 1036
Cdd:COG4886 351 TLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
|
|
| NB-ARC |
pfam00931 |
NB-ARC domain; |
241-477 |
1.48e-16 |
|
NB-ARC domain;
Pssm-ID: 395745 [Multi-domain] Cd Length: 245 Bit Score: 80.50 E-value: 1.48e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 241 AHLEKMKPLLcLDTDEVRIIGIWGPPGIGKTTIARVVYN---QLSHSF----QLSVfmenikanytrptgSDDYSAKLQL 313
Cdd:pfam00931 3 DMVEKVIGKL-SEKDEPGIVGIHGMGGVGKTTLAAQIFNdfdEVEGHFdsvaWVVV--------------SKTFTISTLQ 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 314 QQMFMSQITKQKDIEIPHLGVAQDR----LKDKKVLVVLDGVNQSVQLDAMAKEAWWFGPGSRIIITTQDQKLFRAHGIN 389
Cdd:pfam00931 68 QTILQNLGLSEDDWDNKEEGELARKirraLLTKRFLLVLDDVWDEEDWDKIGIPLPDRENGCRVLLTTRSEEVAGRVGGP 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 390 H-IYKVDFPPTEEALQIFCMYAF-GQNSPKDGFQNLAWKVINLAGNLPLGLRIMGSYFRGMSR-EEWKKSLPRLESSLDA 466
Cdd:pfam00931 148 SdPHEVELLEPDEAWELFENKVFpKTLGECELLEDVAKEIVEKCRGLPLALKVLGGLLSCKKTvEEWKHVYDVLQSELKS 227
|
250
....*....|....*..
gi 15238999 467 D------IQSILKFSYD 477
Cdd:pfam00931 228 NsyslnsVRSILQLSYE 244
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
756-1048 |
1.24e-13 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 74.58 E-value: 1.24e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 756 CSNLVELPSSIGNAINLRELDLYYCSSLIRLPSSIGNAINLLILDLNGCSNLLELPSSIGNAINLQKLDLRRCAKLLELP 835
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 836 SSIGNAINLQNLLLDDCSSLLEL--PSSIGNATNLVYMNLSNCsNLVELPLSIGNLQKLQELILKGCsKLEDLPINI-NL 912
Cdd:COG4886 81 LLSLLLLGLTDLGDLTNLTELDLsgNEELSNLTNLESLDLSGN-QLTDLPEELANLTNLKELDLSNN-QLTDLPEPLgNL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 913 ESLdilvlndcsmlkrfpeistnvRALYLCGTAIEEVPLSIRSWPRLDELLMSYfDNLVEFPHVLDIITNL---DLSGKE 989
Cdd:COG4886 159 TNL---------------------KSLDLSNNQLTDLPEELGNLTNLKELDLSN-NQITDLPEPLGNLTNLeelDLSGNQ 216
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15238999 990 IQEVPPLIKRISRLQTLILkGYRKVVSLPQIPD--SLKWIDAEDCEsLERLDCSFHNPEIT 1048
Cdd:COG4886 217 LTDLPEPLANLTNLETLDL-SNNQLTDLPELGNltNLEELDLSNNQ-LTDLPPLANLTNLK 275
|
|
| TIR_2 |
pfam13676 |
TIR domain; This is a family of Toll-like receptors. |
64-161 |
1.15e-12 |
|
TIR domain; This is a family of Toll-like receptors.
Pssm-ID: 463954 [Multi-domain] Cd Length: 118 Bit Score: 65.80 E-value: 1.15e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 64 VFPSFSGEDvrRDFLSHIQMEFQRMGITPFVD-NEIKRGESIGPELLRAIRGSKIAIILLSRNYASSKWCLDELvEIMKC 142
Cdd:pfam13676 1 VFISYAGED--RAWAEWLADALEAAGYRVWLDrWDIRPGDDWVEEIEEAIENSDRVLVVLSPNYLESPWCRAEW-EAALA 77
|
90
....*....|....*....
gi 15238999 143 REEYGQTVMAIFYKVDPSD 161
Cdd:pfam13676 78 DPEGRKRLIPVRLECDLEL 96
|
|
| C-JID |
pfam20160 |
C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron ... |
1075-1158 |
3.17e-12 |
|
C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron microscopy (cryoEM) structures of plant intracellular immune receptors containing Toll/interleukin-1 receptor (TIR, PF01582), nucleotide-binding (NB-ARC, PF00931) and leucine-rich repeat (LRR) domains (TIR-NLRs). Structurally, the C-JID core is represented by a beta-sandwich made up of 8 to 9 beta-strands. C-JID matches the so-called post LRR domain originally detected via a set of MEME motifs. The domain showed a strong distribution bias towards TIR-NLRs of dicotyledonous plant species despite broader taxonomic distribution of TIR-NLR in plant groups. Structure-function analyses of cryoEM structures suggest that C-JID domains play a role in substrate-recognition, such as binding to effector proteins from pathogens, and thus are involved in the initiation of signaling by TIR-NLR receptors. Presence of C-JID (or post-LRR) and its importance for the function of Arabidopsis TIR-NLR RPS4 that partners with RRS1 for effector recognition suggest that C-JID has additional functions.
Pssm-ID: 466313 Cd Length: 108 Bit Score: 64.00 E-value: 3.17e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 1075 LPGREVPAYFTHRASGGSLTIKLNERPL-PTSMRYKACILLVRIGDYGAHDR-----------------------DKWLH 1130
Cdd:pfam20160 1 LPGSQIPEWFNHQSTGSSISIKLPENWYnDNFLGFAVCAVGSLIPSLHNFLGyihffliplvslwdtskangktpNDYGR 80
|
90 100
....*....|....*....|....*...
gi 15238999 1131 VAFGVRSTTLGHIIYSGLTEHLYTFEIE 1158
Cdd:pfam20160 81 IEASFEFPSDLHEIKQCGVRLIYKDEVE 108
|
|
| PLN03194 |
PLN03194 |
putative disease resistance protein; Provisional |
62-200 |
2.18e-10 |
|
putative disease resistance protein; Provisional
Pssm-ID: 215626 [Multi-domain] Cd Length: 187 Bit Score: 60.99 E-value: 2.18e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 62 HQVFPSFSGEDVRRDFLSHIQMEFQRMGITPFVDNE-IKRGESIGPELLRAIRGSKIAIILLSRNYASSKWCLDELVEIM 140
Cdd:PLN03194 27 CDVFINHRGIDTKRTIATLLYDHLSRLNLRPFLDNKnMKPGDKLFDKINSAIRNCKVGVAVFSPRYCESYFCLHELALIM 106
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15238999 141 KCREEygqtVMAIFYKVDPS--DVKNltgdfgkvfRKTCagkPKKDIGRWRQAWEKVATVAG 200
Cdd:PLN03194 107 ESKKR----VIPIFCDVKPSqlRVVD---------NGTC---PDEEIRRFNWALEEAKYTVG 152
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
675-1044 |
9.18e-10 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 63.33 E-value: 9.18e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 675 LHNLRQMDLSYSVNLKELP-DLSTAINLRKLILSNCSSLIKLPSCIGNAINLEDLDLNGCSSLVELPS-FGDAINLQKLL 752
Cdd:PLN00113 139 IPNLETLDLSNNMLSGEIPnDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPReLGQMKSLKWIY 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 753 LRYCSNLVELPSSIGNAINLRELDLYYCSSLIRLPSSIGNAINL--LILDLNGCSNllELPSSIGNAINLQKLDLR---- 826
Cdd:PLN00113 219 LGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLqyLFLYQNKLSG--PIPPSIFSLQKLISLDLSdnsl 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 827 -----------RCAKLLEL---------PSSIGNAINLQNLLLDDCSSLLELPSSIGNATNLVYMNLSNCSNLVELPLSI 886
Cdd:PLN00113 297 sgeipelviqlQNLEILHLfsnnftgkiPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPEGL 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 887 GNLQKLQELILKGCSKLEDLPININL-ESLDILVLNDCSMLKRFPEISTNVRALYLCGTAIEEVP--LSIRSW--PRLDE 961
Cdd:PLN00113 377 CSSGNLFKLILFSNSLEGEIPKSLGAcRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQgrINSRKWdmPSLQM 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 962 LLMS---YFDNLVEFPHVlDIITNLDLSGKEIQE-VPPLIKRISRLQTLILKGyRKVVSlpQIPDSLkwidaEDCESLER 1037
Cdd:PLN00113 457 LSLArnkFFGGLPDSFGS-KRLENLDLSRNQFSGaVPRKLGSLSELMQLKLSE-NKLSG--EIPDEL-----SSCKKLVS 527
|
....*..
gi 15238999 1038 LDCSfHN 1044
Cdd:PLN00113 528 LDLS-HN 533
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
795-1057 |
3.54e-07 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 54.17 E-value: 3.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 795 NLLILDLNGCSNLLELPSSIGNAINLQKLDLRRCAKLLELPSSIGNAINLQNLLLDDCSSLLELPSSIGNATNLVYMNLS 874
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 875 NCSNLVELPLSIGNLQKLQELILKGCSKLEDLPiniNLESLDilvLNDCSMLKRFPEIS--TNVRALYLCGTAIEEVPLS 952
Cdd:COG4886 81 LLSLLLLGLTDLGDLTNLTELDLSGNEELSNLT---NLESLD---LSGNQLTDLPEELAnlTNLKELDLSNNQLTDLPEP 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 953 IRSWPRLdellmsyfdnlvefphvldiiTNLDLSGKEIQEVPPLIKRISRLQTLILKGYRkvvsLPQIPDSLkwidaEDC 1032
Cdd:COG4886 155 LGNLTNL---------------------KSLDLSNNQLTDLPEELGNLTNLKELDLSNNQ----ITDLPEPL-----GNL 204
|
250 260
....*....|....*....|....*..
gi 15238999 1033 ESLERLDCSfHNP--EITLFFGKCFKL 1057
Cdd:COG4886 205 TNLEELDLS-GNQltDLPEPLANLTNL 230
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
688-890 |
3.63e-05 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 48.15 E-value: 3.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 688 NLKELPDlstaiNLR---KLILSNCSSLIKLPSCIGNAINLEDLDLNGCSSLVE-LPSfgdaiNLQKLLLrYCSNLVELP 763
Cdd:PRK15370 210 ELKSLPE-----NLQgniKTLYANSNQLTSIPATLPDTIQEMELSINRITELPErLPS-----ALQSLDL-FHNKISCLP 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 764 SSIGNAinLRELDLYYcSSLIRLPSSIGNAINLLILDLNgcsNLLELPSSIgnAINLQKLDLRRCAkLLELPSSIGNAin 843
Cdd:PRK15370 279 ENLPEE--LRYLSVYD-NSIRTLPAHLPSGITHLNVQSN---SLTALPETL--PPGLKTLEAGENA-LTSLPASLPPE-- 347
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 15238999 844 LQNLLLDDCSSLLeLPSSIGNATNLVYMNLSNCSNLVE-LPLSIGNLQ 890
Cdd:PRK15370 348 LQVLDVSKNQITV-LPETLPPTITTLDVSRNALTNLPEnLPAALQIMQ 394
|
|
| CDC6 |
COG1474 |
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]; |
262-353 |
3.80e-05 |
|
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
Pssm-ID: 441083 [Multi-domain] Cd Length: 389 Bit Score: 47.54 E-value: 3.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 262 IWGPPGIGKTTIARVVYNQL-----SHSFQLSVFMENIKANYTRptgsddYSAklqlqqmfMSQITKQ--KDIEIPHLGV 334
Cdd:COG1474 56 IYGPTGTGKTAVAKYVLEELeeeaeERGVDVRVVYVNCRQASTR------YRV--------LSRILEElgSGEDIPSTGL 121
|
90 100
....*....|....*....|....*....
gi 15238999 335 AQDRL----------KDKKVLVVLDGVNQ 353
Cdd:COG1474 122 STDELfdrlyealdeRDGVLVVVLDEIDY 150
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
676-875 |
1.33e-04 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 46.38 E-value: 1.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 676 HNLRQMDLSYSVNLKELPD-LSTAINLRKLILSNCSSLIKLPSCIGNAINLEDLDLNGCSSLVELPS---------FGDA 745
Cdd:PLN00113 356 NNLTVLDLSTNNLTGEIPEgLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELPSeftklplvyFLDI 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 746 IN----------------LQKLLLRYCSNLVELPSSIGNAiNLRELDLYYCSSLIRLPSSIGNAINLLILDLNGCSNLLE 809
Cdd:PLN00113 436 SNnnlqgrinsrkwdmpsLQMLSLARNKFFGGLPDSFGSK-RLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGE 514
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15238999 810 LPSSIGNAINLQKLDLRRCAKLLELPSSIGNAINLQNLLLDDCSSLLELPSSIGNATNLVYMNLSN 875
Cdd:PLN00113 515 IPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISH 580
|
|
| RarA |
COG2256 |
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ... |
263-288 |
2.78e-04 |
|
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];
Pssm-ID: 441857 [Multi-domain] Cd Length: 439 Bit Score: 44.66 E-value: 2.78e-04
10 20
....*....|....*....|....*..
gi 15238999 263 WGPPGIGKTTIARVVYNQLSHSF-QLS 288
Cdd:COG2256 55 WGPPGTGKTTLARLIANATDAEFvALS 81
|
|
| LRR_3 |
pfam07725 |
Leucine Rich Repeat; This Pfam entry includes some LRRs that fail to be detected by the ... |
654-673 |
3.01e-04 |
|
Leucine Rich Repeat; This Pfam entry includes some LRRs that fail to be detected by the pfam00560 model.
Pssm-ID: 429621 [Multi-domain] Cd Length: 20 Bit Score: 38.86 E-value: 3.01e-04
|
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
263-295 |
4.95e-04 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 43.92 E-value: 4.95e-04
10 20 30
....*....|....*....|....*....|....
gi 15238999 263 WGPPGIGKTTIARVVYNQLSHSF-QLSVFMENIK 295
Cdd:PRK13342 42 WGPPGTGKTTLARIIAGATDAPFeALSAVTSGVK 75
|
|
| COG4916 |
COG4916 |
Uncharacterized conserved protein [Function unknown]; |
62-170 |
8.78e-04 |
|
Uncharacterized conserved protein [Function unknown];
Pssm-ID: 443944 [Multi-domain] Cd Length: 236 Bit Score: 42.41 E-value: 8.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 62 HQVFPSFSGEDvrRDFLSHIQMEFQRMGITPFVDNEiKRGESIGPELLRAI-----RGSKIAIILLSRNYASSKWCLDEL 136
Cdd:COG4916 1 YDVALSFAGED--REFVERVAEALKARGIKVFYDEN-EEAELWGKDLDEYLqdiyrSESRFVVVFLSKDYVEKKWTGLER 77
|
90 100 110
....*....|....*....|....*....|....
gi 15238999 137 vEIMKCREEYGQTVMAIFYKVDPSDVKNLTGDFG 170
Cdd:COG4916 78 -RAALARAMQRKKEYILPIRLDDTEIPGILATIG 110
|
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
237-524 |
1.49e-03 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 42.87 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 237 VGMRAHLEKMKPLLCLDTDEVRIIgIWGPPGIGKTTIARVVYNQLSHSFQLS-----VFMEnIKanytrptgsdDYSAKL 311
Cdd:COG5635 161 LNLLERIESLKRLELLEAKKKRLL-ILGEPGSGKTTLLRYLALELAERYLDAedpipILIE-LR----------DLAEEA 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 312 QLQQMFMSQITKQKDIEIPHLgvaQDRLKDKKVLVVLDG---VNQSVQLDAMAKEAWWFG---PGSRIIITTqdqklfRA 385
Cdd:COG5635 229 SLEDLLAEALEKRGGEPEDAL---ERLLRNGRLLLLLDGldeVPDEADRDEVLNQLRRFLeryPKARVIITS------RP 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 386 HGINHIYKVDF------PPTEEALQIFCMYAFGQNSPK-DGFQNLAWK---VINLAGNlPLGLRIMGSYFRGmsreewKK 455
Cdd:COG5635 300 EGYDSSELEGFevlelaPLSDEQIEEFLKKWFEATERKaERLLEALEEnpeLRELARN-PLLLTLLALLLRE------RG 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 456 SLPR---------LESSLDADIQSILKFSYDALDDEDKNLFL-HIA--------CFFNGKEI-KILEEHLAKKfVEVRQR 516
Cdd:COG5635 373 ELPDtraelyeqfVELLLERWDEQRGLTIYRELSREELRELLsELAlamqengrTEFAREELeEILREYLGRR-KDAEAL 451
|
....*...
gi 15238999 517 LNVLAEKS 524
Cdd:COG5635 452 LDELLLRT 459
|
|
| AMN1 |
cd09293 |
Antagonist of mitotic exit network protein 1; Amn1 has been functionally characterized in ... |
757-932 |
1.72e-03 |
|
Antagonist of mitotic exit network protein 1; Amn1 has been functionally characterized in Saccharomyces cerevisiae as a component of the Antagonist of MEN pathway (AMEN). The AMEN network is activated by MEN (mitotic exit network) via an active Cdc14, and in turn switches off MEN. Amn1 constitutes one of the alternative mechanisms by which MEN may be disrupted. Specifically, Amn1 binds Tem1 (Termination of M-phase, a GTPase that belongs to the RAS superfamily), and disrupts its association with Cdc15, the primary downstream target. Amn1 is a leucine-rich repeat (LRR) protein, with 12 repeats in the S. cerevisiae ortholog. As a negative regulator of the signal transduction pathway MEN, overexpression of AMN1 slows the growth of wild type cells. The function of the vertebrate members of this family has not been determined experimentally, they have fewer LRRs that determine the extent of this model.
Pssm-ID: 187754 [Multi-domain] Cd Length: 226 Bit Score: 41.16 E-value: 1.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 757 SNLVELPSSIGNaiNLRELDLYYCSSLIRLPSSIGNAINLLILDLNGCSN-----LLELPSSIGnaiNLQKLDLRRCAKL 831
Cdd:cd09293 17 SNISQLLRILHS--GLEWLELYMCPISDPPLDQLSNCNKLKKLILPGSKLiddegLIALAQSCP---NLQVLDLRACENI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 832 lelpSSIG-----------NAINLQNLLLDDCSSLLELPSSIGNATNLVYMNLSNC--SNLVELPLSIGNLQKLQELILK 898
Cdd:cd09293 92 ----TDSGivalatncpklQTINLGRHRNGHLITDVSLSALGKNCTFLQTVGFAGCdvTDKGVWELASGCSKSLERLSLN 167
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 15238999 899 GCSKLEDLPININLES-----LDILVLNDCSMLKRF-PEI 932
Cdd:cd09293 168 NCRNLTDQSIPAILASnyfpnLSVLEFRGCPLITDFsRII 207
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
761-815 |
6.02e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 40.57 E-value: 6.02e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 15238999 761 ELPSSIGNAINLRELDLYYCSSLIRLPSSIGNAINLLILDLNGCSNLLELPSSIG 815
Cdd:PLN03150 457 NIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAALG 511
|
|
| cdc6 |
PRK00411 |
ORC1-type DNA replication protein; |
262-352 |
8.38e-03 |
|
ORC1-type DNA replication protein;
Pssm-ID: 234751 [Multi-domain] Cd Length: 394 Bit Score: 39.83 E-value: 8.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15238999 262 IWGPPGIGKTTIARVVYNQLS-HSFQLSVFMENIKANYTRptgsddYSAklqlqqmfMSQITKQ-KDIEIPHLGVAQDRL 339
Cdd:PRK00411 60 IYGPPGTGKTTTVKKVFEELEeIAVKVVYVYINCQIDRTR------YAI--------FSEIARQlFGHPPPSSGLSFDEL 125
|
90 100
....*....|....*....|...
gi 15238999 340 ----------KDKKVLVVLDGVN 352
Cdd:PRK00411 126 fdkiaeyldeRDRVLIVALDDIN 148
|
|
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