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    EAP30/Vps36 family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830374, updated on 18-Sep-2024

    Summary

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    Official Full Name
    EAP30/Vps36 family protein
    Primary source
    TAIR:AT5G04920
    Locus tag
    AT5G04920
    See related
    Araport:AT5G04920
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MUG13.23; MUG13_23; VPS36
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    9
    Sequence:
    Chromosome: 5; NC_003076.8 (1438959..1442017, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene DEA(D/H)-box RNA helicase family protein Neighboring gene NYC1-like protein Neighboring gene DNA repair REX1-B protein Neighboring gene aminophospholipid ATPase 1 Neighboring gene Pol-like polyprotein/retrotransposon

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. VPS36-Dependent Multivesicular Bodies Are Critical for Plasmamembrane Protein Turnover and Vacuolar Biogenesis. Wang HJ, et al. Plant Physiol, 2017 Jan. PMID 27879389, Free PMC Article
    2. The Arabidopsis ESCRT protein-protein interaction network. Shahriari M, et al. Plant Mol Biol, 2011 May. PMID 21442383
    3. The Arabidopsis elch mutant reveals functions of an ESCRT component in cytokinesis. Spitzer C, et al. Development, 2006 Dec. PMID 17090720
    4. Protein-Protein Interaction Network and Subcellular Localization of the Arabidopsis Thaliana ESCRT Machinery. Richardson LG, et al. Front Plant Sci, 2011. PMID 22639582, Free PMC Article
    5. Exploring the ESCRTing machinery in eukaryotes. Winter V, et al. Trends Plant Sci, 2006 Mar. PMID 16488176, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. VPS36 is essential for a proper endosomal sorting pathway and for vacuolar biogenesis in Arabidopsis.
      Title: VPS36-Dependent Multivesicular Bodies Are Critical for Plasmamembrane Protein Turnover and Vacuolar Biogenesis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_120574.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phosphatidylinositol-3-phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in endosome transport via multivesicular body sorting pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within multivesicular body sorting pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within seedling development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within vacuole organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within vesicle-mediated transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ESCRT II complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in early endosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in late endosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    EAP30/Vps36 family protein
    NP_196112.1
    • EAP30/Vps36 family protein; CONTAINS InterPro DOMAIN/s: EAP30 (InterPro:IPR007286), Vacuolar protein sorting protein, Vps36 (InterPro:IPR021648); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      1438959..1442017 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120574.5 → NP_196112.1  EAP30/Vps36 family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196112.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WQI2, Q9FF81
      UniProtKB/TrEMBL
      A0A178U8Z1, A0A5S9Y2A8
      Conserved Domains (2) summary
      pfam04157
      Location:174 → 398
      EAP30; EAP30/Vps36 family
      pfam11605
      Location:18 → 111
      Vps36_ESCRT-II; Vacuolar protein sorting protein 36 Vps36
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FF81.1

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