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    CG4462 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42376, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4462provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038752
    Locus tag
    Dmel_CG4462
    See related
    AllianceGenome:FB:FBgn0038752
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4462
    Summary
    Predicted to enable organic anion transmembrane transporter activity. Predicted to be involved in organic anion transport. Predicted to be located in plasma membrane. Is expressed in adult head and seminal receptacle. Orthologous to human SLC22A15 (solute carrier family 22 member 15). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4462 in Genome Data Viewer
    Location:
    92B7-92B8; 3-67 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (19921744..19925371, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15747466..15751093, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA::CR43282 Neighboring gene long non-coding RNA:CR46040 Neighboring gene hairpin RNA 1 Neighboring gene uncharacterized protein Neighboring gene Heparan sulfate 6-O-sulfotransferase Neighboring gene miranda

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Anion-sensitive fluorophore identifies the Drosophila swell-activated chloride channel in a genome-wide RNA interference screen. Stotz SC, et al. PLoS One, 2012. PMID 23056495, Free PMC Article
    2. Adaptive regulation of testis gene expression and control of male fertility by the Drosophila hairpin RNA pathway. [Corrected]. Wen J, et al. Mol Cell, 2015 Jan 8. PMID 25544562, Free PMC Article
    3. Transcriptional profiling of the sperm storage organs of Drosophila melanogaster. Prokupek AM, et al. Insect Mol Biol, 2009 Aug. PMID 19453766
    4. Genetic architecture of natural variation in visual senescence in Drosophila. Carbone MA, et al. Proc Natl Acad Sci U S A, 2016 Oct 25. PMID 27791033, Free PMC Article
    5. Crtc modulates fasting programs associated with 1-C metabolism and inhibition of insulin signaling. Wang T, et al. Proc Natl Acad Sci U S A, 2021 Mar 23. PMID 33723074, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables organic anion transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in organic anion transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4462-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      19921744..19925371 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142592.2 → NP_650849.1  uncharacterized protein Dmel_CG4462 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650849.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VDS0
      Related
      FBpp0083259
      Conserved Domains (2) summary
      cd06174
      Location:149 → 284
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00898
      Location:126 → 532
      2A0119; cation transport protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SXB7 Q8SXB7
    Q9VDS0 Q9VDS0

    Gene LinkOut

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