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    Zbtb8os zinc finger and BTB domain containing 8 opposite strand [ Mus musculus (house mouse) ]

    Gene ID: 67106, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zbtb8osprovided by MGI
    Official Full Name
    zinc finger and BTB domain containing 8 opposite strandprovided by MGI
    Primary source
    MGI:MGI:1914356
    See related
    Ensembl:ENSMUSG00000057572 AllianceGenome:MGI:1914356
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Arch; Archm; 2010001H09Rik; 2310028N13Rik
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to be part of tRNA-splicing ligase complex. Is expressed in brain and embryo. Orthologous to human ZBTB8OS (zinc finger and BTB domain containing 8 opposite strand). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 10.5), CNS E11.5 (RPKM 8.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Zbtb8os in Genome Data Viewer
    Location:
    4 D2.2; 4 63.26 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (129229325..129243664)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (129335532..129349871)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene NHS like 3 Neighboring gene STARR-seq mESC enhancer starr_11482 Neighboring gene predicted gene 12976 Neighboring gene STARR-positive B cell enhancer ABC_E7991 Neighboring gene syncoilin Neighboring gene retinoblastoma binding protein 4, chromatin remodeling factor Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:129012802-129012911 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:129013051-129013391 Neighboring gene zinc finger and BTB domain containing 8a Neighboring gene STARR-seq mESC enhancer starr_11489 Neighboring gene STARR-seq mESC enhancer starr_11490 Neighboring gene RIKEN cDNA C330020E22 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding  
    enables molecular_function  
    Component Evidence Code Pubs
    part_of tRNA-splicing ligase complex  
    part_of tRNA-splicing ligase complex  
    part_of tRNA-splicing ligase complex  

    General protein information

    Preferred Names
    protein archease
    Names
    archease (Arch)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025970.4NP_080246.1  protein archease

      See identical proteins and their annotated locations for NP_080246.1

      Status: VALIDATED

      Source sequence(s)
      AL607123
      Consensus CDS
      CCDS18689.1
      UniProtKB/Swiss-Prot
      Q505B7, Q8R0S8, Q9CQ53, Q9D770
      UniProtKB/TrEMBL
      B2KGA7
      Related
      ENSMUSP00000120925.2, ENSMUST00000141235.8
      Conserved Domains (1) summary
      pfam01951
      Location:31167
      Archease; Archease protein family (MTH1598/TM1083)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      129229325..129243664
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006503304.5XP_006503367.1  protein archease isoform X1

      See identical proteins and their annotated locations for XP_006503367.1

      Conserved Domains (1) summary
      pfam01951
      Location:1110
      Archease; Archease protein family (MTH1598/TM1083)
    2. XM_017320361.3XP_017175850.1  protein archease isoform X2

      UniProtKB/TrEMBL
      A8Y5E9
      Related
      ENSMUSP00000113004.2, ENSMUST00000119480.2
      Conserved Domains (1) summary
      pfam01951
      Location:43121
      Archease; Archease protein family (MTH1598/TM1083)
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