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Conserved domains on  [gi|1039768464|ref|XP_017175850|]
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protein archease isoform X2 [Mus musculus]

Protein Classification

archease( domain architecture ID 10487813)

archease is a component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of the catalytic subunit RTCB

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Archease pfam01951
Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 ...
 43-121 1.77e-40

Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 domains, with one inserted into another. It is predicted to be an enzyme. It is predicted to act as a chaperone in DNA/RNA metabolism.


:

Pssm-ID: 426527  Cd Length: 136  Bit Score: 132.27  E-value: 1.77e-40
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039768464  43 YEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTGTVEPLRTVEVETQGDDLQSLLFHFLDEWLYKFSAdEYFIPR 121
Cdd:pfam01951   1 YEYLDHTADVGIEAWGPTLEEAFENAALAMFELMTDLSKVEPKEEREIEVEGEDLEDLLVDWLDELLYLFDT-EGLVFS 78
 
Name Accession Description Interval E-value
Archease pfam01951
Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 ...
 43-121 1.77e-40

Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 domains, with one inserted into another. It is predicted to be an enzyme. It is predicted to act as a chaperone in DNA/RNA metabolism.


Pssm-ID: 426527  Cd Length: 136  Bit Score: 132.27  E-value: 1.77e-40
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039768464  43 YEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTGTVEPLRTVEVETQGDDLQSLLFHFLDEWLYKFSAdEYFIPR 121
Cdd:pfam01951   1 YEYLDHTADVGIEAWGPTLEEAFENAALAMFELMTDLSKVEPKEEREIEVEGEDLEDLLVDWLDELLYLFDT-EGLVFS 78
ARCH COG1371
Archease, activates RNA ligation by RtcB (tRNA splicing) [Translation, ribosomal structure and ...
 41-121 6.25e-30

Archease, activates RNA ligation by RtcB (tRNA splicing) [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440982  Cd Length: 139  Bit Score: 105.26  E-value: 6.25e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768464  41 RKYEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTGTVEPLRTVEVETQGDDLQSLLFHFLDEWLYKFSAdEYFIP 120
Cdd:COG1371     1 MGYEFLDHTADVGIEAYGPTLEEAFANAALALFALMVDTSKVEPREEREIEVEAEDLEDLLVDWLNELLYLFDT-EGLLF 79


                  .
gi 1039768464 121 R 121
Cdd:COG1371    80 S 80
Archease PRK00407
Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 ...
 41-110 9.63e-24

Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 domains, with one inserted into another. It is predicted to be an enzyme. It is predicted to act as a chaperone in DNA/RNA metabolism.


Pssm-ID: 179008  Cd Length: 139  Bit Score: 89.69  E-value: 9.63e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768464  41 RKYEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTGTVEPLRTVEVETQGDDLQSLLFHFLDEWLY 110
Cdd:PRK00407    2 RSYEFFEHTADIGIRAYGRTLEEAFENAALAVFDVITDTSKVEPKEEREIEIEGYDLENLLYRWLEELLY 71
 
Name Accession Description Interval E-value
Archease pfam01951
Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 ...
 43-121 1.77e-40

Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 domains, with one inserted into another. It is predicted to be an enzyme. It is predicted to act as a chaperone in DNA/RNA metabolism.


Pssm-ID: 426527  Cd Length: 136  Bit Score: 132.27  E-value: 1.77e-40
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039768464  43 YEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTGTVEPLRTVEVETQGDDLQSLLFHFLDEWLYKFSAdEYFIPR 121
Cdd:pfam01951   1 YEYLDHTADVGIEAWGPTLEEAFENAALAMFELMTDLSKVEPKEEREIEVEGEDLEDLLVDWLDELLYLFDT-EGLVFS 78
ARCH COG1371
Archease, activates RNA ligation by RtcB (tRNA splicing) [Translation, ribosomal structure and ...
 41-121 6.25e-30

Archease, activates RNA ligation by RtcB (tRNA splicing) [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440982  Cd Length: 139  Bit Score: 105.26  E-value: 6.25e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768464  41 RKYEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTGTVEPLRTVEVETQGDDLQSLLFHFLDEWLYKFSAdEYFIP 120
Cdd:COG1371     1 MGYEFLDHTADVGIEAYGPTLEEAFANAALALFALMVDTSKVEPREEREIEVEAEDLEDLLVDWLNELLYLFDT-EGLLF 79


                  .
gi 1039768464 121 R 121
Cdd:COG1371    80 S 80
Archease PRK00407
Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 ...
 41-110 9.63e-24

Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 domains, with one inserted into another. It is predicted to be an enzyme. It is predicted to act as a chaperone in DNA/RNA metabolism.


Pssm-ID: 179008  Cd Length: 139  Bit Score: 89.69  E-value: 9.63e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768464  41 RKYEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTGTVEPLRTVEVETQGDDLQSLLFHFLDEWLY 110
Cdd:PRK00407    2 RSYEFFEHTADIGIRAYGRTLEEAFENAALAVFDVITDTSKVEPKEEREIEIEGYDLENLLYRWLEELLY 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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