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    CG8301 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41160, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8301provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037717
    Locus tag
    Dmel_CG8301
    See related
    AllianceGenome:FB:FBgn0037717
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8301
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in organism. Orthologous to human ZNF311 (zinc finger protein 311) and ZNF578 (zinc finger protein 578). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8301 in Genome Data Viewer
    Location:
    85D26-85D27; 3-48 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9581306..9586648)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5407028..5412370)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene karyopherin alpha3 Neighboring gene Son RNA binding protein Neighboring gene uncharacterized protein Neighboring gene P58IPK Neighboring gene bocksbeutel Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Hrp59, an hnRNP M protein in Chironomus and Drosophila, binds to exonic splicing enhancers and is required for expression of a subset of mRNAs. Kiesler E, et al. J Cell Biol, 2005 Mar 28. PMID 15781475, Free PMC Article
    2. Stable intronic sequence RNAs have possible regulatory roles in Drosophila melanogaster. Pek JW, et al. J Cell Biol, 2015 Oct 26. PMID 26504165, Free PMC Article
    3. An RNA-interference screen in Drosophila to identify ZAD-containing C2H2 zinc finger genes that function in female germ cells. Shapiro-Kulnane L, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561227, Free PMC Article
    4. Amyotrophic Lateral Sclerosis Modifiers in Drosophila Reveal the Phospholipase D Pathway as a Potential Therapeutic Target. Kankel MW, et al. Genetics, 2020 Jul. PMID 32345615, Free PMC Article
    5. ZAD-Domain Is Essential for Nuclear Localization of Insulator Proteins in Drosophila melanogaster. Zolotarev NA, et al. Acta Naturae, 2016 Jul-Sep. PMID 27795848, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8301-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      9581306..9586648
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141658.5 → NP_649915.1  uncharacterized protein Dmel_CG8301 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649915.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VHA9
      Related
      FBpp0081551
      Conserved Domains (3) summary
      COG5048
      Location:198 → 508
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:480 → 500
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:3 → 87
      zf-AD; Zinc-finger associated domain (zf-AD)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VHA9 Q9VHA9

    Gene LinkOut

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