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    sult6b1 sulfotransferase family, cytosolic, 6b, member 1 [ Danio rerio (zebrafish) ]

    Gene ID: 322462, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sult6b1provided by ZNC
    Official Full Name
    sulfotransferase family, cytosolic, 6b, member 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-228
    See related
    Ensembl:ENSDARG00000086826 AllianceGenome:ZFIN:ZDB-GENE-050417-228
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sb:cb89; wu:fb62a12; zgc:111843
    Summary
    Enables sulfotransferase activity. Acts upstream of or within cellular response to xenobiotic stimulus. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in several structures, including EVL; digestive system; ectoderm; forerunner cell group; and tail bud. Orthologous to human SULT6B1 (sulfotransferase family 6B member 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See sult6b1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (43375360..43387747)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (43083167..43095486)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene spectrin, beta, non-erythrocytic 1 Neighboring gene uncharacterized LOC137496738 Neighboring gene vasoactive intestinal peptide b Neighboring gene solute carrier family 29 member 1b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning, expression, and functional characterization of a novel zebrafish cytosolic sulfotransferase. Sugahara T, et al. Biochem Biophys Res Commun, 2003 Jan 17. PMID 12507510
    2. Identification and characterization of two novel cytosolic sulfotransferases, SULT1 ST7 and SULT1 ST8, from zebrafish. Liu TA, et al. Aquat Toxicol, 2008 Aug 29. PMID 18632167
    3. Host monitoring of quorum sensing during Pseudomonas aeruginosa infection. Moura-Alves P, et al. Science, 2019 Dec 20. PMID 31857448
    4. Down-Regulation of hspb9 and hspb11 Contributes to Wavy Notochord in Zebrafish Embryos Following Exposure to Polychlorinated Diphenylsulfides. Zhang R, et al. Environ Sci Technol, 2018 Nov 6. PMID 30335980
    5. Structurally distinct polycyclic aromatic hydrocarbons induce differential transcriptional responses in developing zebrafish. Goodale BC, et al. Toxicol Appl Pharmacol, 2013 Nov 1. PMID 23656968, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. results constitute a first study on the cloning, expression, and characterization of a zebrafish cytosolic sulfotransferase
      Title: Molecular cloning, expression, and functional characterization of a novel zebrafish cytosolic sulfotransferase.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sulfotransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables sulfotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to xenobiotic stimulus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in sulfation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sulfotransferase 6B1
    Names
    thyroxine sulfotransferase
    NP_999851.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214686.2 → NP_999851.2  sulfotransferase 6B1

      Status: VALIDATED

      Source sequence(s)
      CU929458
      UniProtKB/Swiss-Prot
      F1QYJ6, Q567N1, Q800X2
      Related
      ENSDARP00000105990.1, ENSDART00000130131.4
      Conserved Domains (1) summary
      pfam00685
      Location:48 → 283
      Sulfotransfer_1; Sulfotransferase domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      43375360..43387747
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F1QYJ6.1 GenPept UniProtKB/Swiss-Prot:F1QYJ6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.