plagl2 pleiomorphic adenoma gene-like 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: plagl2provided by ZNC
Official Full Name: pleiomorphic adenoma gene-like 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-020806-1
See related: Ensembl:ENSDARG00000076657 AllianceGenome:ZFIN:ZDB-GENE-020806-1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including axial vasculature; immature eye; lateral plate mesoderm; nervous system; and otic vesicle. Orthologous to human PLAGL2 (PLAG1 like zinc finger 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 23

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (7590709..7674851, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (7653870..7741139, complement)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: zinc finger protein PLAGL2

Names: pleiomorphic adenoma protein-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_153652.2 → NP_705938.1 zinc finger protein PLAGL2

See identical proteins and their annotated locations for NP_705938.1

Status: PROVISIONAL

Source sequence(s)

AF186476

UniProtKB/TrEMBL

Q9DG49

Related

ENSDARP00000104090.2, ENSDART00000115298.3

Conserved Domains (2) summary

sd00017
Location:56 → 76

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam13465
Location:99 → 123

zf-H2C2_2; Zinc-finger double domain