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    GT-1 Homeodomain-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837905, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GT-1
    Official Full Name
    Homeodomain-like superfamily protein
    Primary source
    TAIR:AT1G13450
    Locus tag
    AT1G13450
    See related
    Araport:AT1G13450
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T6J4.18; T6J4_18
    Summary
    Encodes GT-1, a plant transcription factor that binds to one of the cis-acting elements, BoxII, which resides within the upstream promoter region of light-responsive genes. GT-1 was assumed to act as a molecular switch modulated through Ca(2+)-dependent phosphorylation/dephosphorylation in response to light signals.
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    Genomic context

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    See GT-1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (4612731..4615353, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase C2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Protein phosphatase 2A regulatory B subunit family protein Neighboring gene hypothetical protein (DUF1262)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Solution structures of the trihelix DNA-binding domains of the wild-type and a phosphomimetic mutant of Arabidopsis GT-1: mechanism for an increase in DNA-binding affinity through phosphorylation. Nagata T, et al. Proteins, 2010 Nov 1. PMID 20717979
    2. Molecular dissection of GT-1 from Arabidopsis. Hiratsuka K, et al. Plant Cell, 1994 Dec. PMID 7866025, Free PMC Article
    3. A stele-enriched gene regulatory network in the Arabidopsis root. Brady SM, et al. Mol Syst Biol, 2011 Jan 18. PMID 21245844, Free PMC Article
    4. Analysis of the Arabidopsis nuclear proteome and its response to cold stress. Bae MS, et al. Plant J, 2003 Dec. PMID 14617066
    5. An Arabidopsis gene regulatory network for secondary cell wall synthesis. Taylor-Teeples M, et al. Nature, 2015 Jan 29. PMID 25533953, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001123807.2
    NM_001332067.1
    NM_001332068.1
    NM_101215.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Homeodomain-like superfamily protein
    NP_001117279.1
    • Homeodomain-like superfamily protein; CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), MYB-like (InterPro:IPR017877); BEST Arabidopsis thaliana protein match is: Homeodomain-like superfamily protein (TAIR:AT3G25990.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001318993.1
    • Homeodomain-like superfamily protein; CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), MYB-like (InterPro:IPR017877); BEST Arabidopsis thaliana protein match is: Homeodomain-like superfamily protein (TAIR:AT3G25990.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_172802.2
    • Homeodomain-like superfamily protein; FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), MYB-like (InterPro:IPR017877); BEST Arabidopsis thaliana protein match is: Homeodomain-like superfamily protein (TAIR:AT3G25990.1); Has 629 Blast hits to 540 proteins in 66 species: Archae - 0; Bacteria - 1; Metazoa - 110; Fungi - 7; Plants - 508; Viruses - 0; Other Eukaryotes - 3 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      4612731..4615353 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101215.4 → NP_172802.2  Homeodomain-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172802.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3H720, Q2L6T7, Q39116, Q9FX53
      UniProtKB/TrEMBL
      A0A178WM96, A0A5S9U826
      Conserved Domains (1) summary
      cd12203
      Location:85 → 150
      GT1; GT1, myb-like, SANT family

    2. NM_001123807.2 → NP_001117279.1  Homeodomain-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001117279.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FX53
      Conserved Domains (1) summary
      cd12203
      Location:85 → 150
      GT1; GT1, myb-like, SANT family

    3. NM_001332067.1 → NP_001318993.1  Homeodomain-like superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FX53

    4. NM_001332068.1 → NP_001322285.1  Homeodomain-like superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WL53, A0A1P8ATI8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FX53.1

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