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    AGL65 AGAMOUS-like 65 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838457, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AGL65
    Official Full Name
    AGAMOUS-like 65
    Primary source
    TAIR:AT1G18750
    Locus tag
    AT1G18750
    See related
    Araport:AT1G18750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AGAMOUS-like 65; F6A14.14; F6A14_14
    Summary
    Encodes a member of the MIKC (MADS box, Keratin binding domain, and C terminal domain containing)family of transcriptional regulators. AGL65 is expressed in pollen.It forms heterodimers with other MICK family members (AGL104). Involved in late stages of pollen development and pollen tube growth.
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    Genomic context

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    See AGL65 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Sequence:
    Chromosome: 1; NC_003070.9 (6466667..6469984)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Zinc finger, C3HC4 type (RING finger) family protein Neighboring gene RING/U-box superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. MIKC* MADS domain heterodimers are required for pollen maturation and tube growth in Arabidopsis. Adamczyk BJ, et al. Plant Physiol, 2009 Apr. PMID 19211705, Free PMC Article
    2. MIKC* MADS-protein complexes bind motifs enriched in the proximal region of late pollen-specific Arabidopsis promoters. Verelst W, et al. Plant Physiol, 2007 Jan. PMID 17071640, Free PMC Article
    3. Comprehensive interaction map of the Arabidopsis MADS Box transcription factors. de Folter S, et al. Plant Cell, 2005 May. PMID 15805477, Free PMC Article
    4. Molecular and phylogenetic analyses of the complete MADS-box transcription factor family in Arabidopsis: new openings to the MADS world. Parenicová L, et al. Plant Cell, 2003 Jul. PMID 12837945, Free PMC Article
    5. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Riechmann JL, et al. Science, 2000 Dec 15. PMID 11118137

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001035989.1
    NM_001332368.1
    NM_001332369.1
    NM_101733.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within pollen development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in pollen maturation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of pollen tube growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    AGAMOUS-like 65
    NP_001031066.1
    • AGAMOUS-like 65 (AGL65); BEST Arabidopsis thaliana protein match is: AGAMOUS-like 30 (TAIR:AT2G03060.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_173310.2
    • AGAMOUS-like 65 (AGL65); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: pollen development; LOCATED IN: nucleus; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Transcription factor, MADS-box (InterPro:IPR002100); BEST Arabidopsis thaliana protein match is: AGAMOUS-like 30 (TAIR:AT2G03060.2); Has 6713 Blast hits to 6650 proteins in 771 species: Archae - 0; Bacteria - 0; Metazoa - 853; Fungi - 361; Plants - 5148; Viruses - 0; Other Eukaryotes - 351 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6466667..6469984
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001332366.1 → NP_001321504.1  AGAMOUS-like 65 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AR61

    2. NM_001332367.1 → NP_001321506.1  AGAMOUS-like 65 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9V2D3, A0A7G2DUA3
      Conserved Domains (1) summary
      cd00266
      Location:2 → 82
      MADS_SRF_like; SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in ...

    3. NM_101733.6 → NP_173310.2  AGAMOUS-like 65 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173310.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q76K80, Q7X9I0, Q9M9U6
      UniProtKB/TrEMBL
      A0A654EB35, A0A7G2DUA3
      Conserved Domains (1) summary
      cd00266
      Location:2 → 82
      MADS_SRF_like; SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in ...

    4. NM_001035989.1 → NP_001031066.1  AGAMOUS-like 65 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031066.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W7R6, F4ICD1

    5. NM_001332368.1 → NP_001321505.1  AGAMOUS-like 65 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W7R6, A0A1P8AR45

    6. NM_001332369.1 → NP_001321507.1  AGAMOUS-like 65 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W7R6, A0A1P8AR88
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7X9I0.1

    Gene LinkOut

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