got1.S glutamic-oxaloacetic transaminase 1 homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: got1.S
Official Full Name: glutamic-oxaloacetic transaminase 1 homeolog
Primary source: Xenbase:XB-GENE-954936
Locus tag: XELAEV_18037056mg
See related: EnsemblRapid:ENSXLAG00005028905 AllianceGenome:Xenbase:XB-GENE-954936
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: got1; xr406
Summary: Predicted to enable L-aspartate:2-oxoglutarate aminotransferase activity and pyridoxal phosphate binding activity. Predicted to act upstream of or within amino acid metabolic process and biosynthetic process. Is expressed in anatomical system; mesoderm; and pharyngeal arch. Human ortholog(s) of this gene implicated in amyloidosis; amyotrophic lateral sclerosis; pancreatic ductal adenocarcinoma; and transient cerebral ischemia. Orthologous to human GOT1 (glutamic-oxaloacetic transaminase 1). [provided by Alliance of Genome Resources, Jan 2025]
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 7S

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	7S	NC_054384.1 (26282557..26293021)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	7S	NC_030737.1 (25756122..25766349)

Chromosome 7S - NC_054384.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables L-aspartate:2-oxoglutarate aminotransferase activity	IEA Inferred from Electronic Annotation more info
enables pyridoxal phosphate binding	IEA Inferred from Electronic Annotation more info
enables transaminase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within amino acid metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within biosynthetic process	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: glutamic-oxaloacetic transaminase 1 homeolog

Names: Aspartate aminotransferase; glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1); glutamic-oxaloacetic transaminase 1, soluble S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001087074.1 → NP_001080543.1 glutamic-oxaloacetic transaminase 1 homeolog

See identical proteins and their annotated locations for NP_001080543.1

Status: PROVISIONAL

Source sequence(s)

BC045269

UniProtKB/TrEMBL

A0A974CBC0, Q7ZTK9

Related

ENSXLAP00005086303.1, ENSXLAT00005087965.1

Conserved Domains (2) summary

PTZ00376
Location:1 → 410

PTZ00376; aspartate aminotransferase; Provisional

pfam00155
Location:31 → 403

Aminotran_1_2; Aminotransferase class I and II