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Conserved domains on  [gi|147903225|ref|NP_001080543|]
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glutamic-oxaloacetic transaminase 1 homeolog [Xenopus laevis]

Protein Classification

aspartate aminotransferase( domain architecture ID 10794389)

aspartate aminotransferase catalyzes the conversion of 2-oxoglutarate and L-aspartate to L-glutamate and oxaloacetate and plays a major role in the metabolism of amino acids and organic acids related to the Krebs cycle

CATH:  3.40.640.10|3.90.1150.10
EC:  2.6.1.-
Gene Ontology:  GO:0008483|GO:0006520|GO:0030170
PubMed:  24121043|32093839
SCOP:  4000670

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PTZ00376 PTZ00376
aspartate aminotransferase; Provisional
 1-410 0e+00

aspartate aminotransferase; Provisional


:

Pssm-ID: 240390  Cd Length: 404  Bit Score: 625.80  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225   1 MASIFCSVPQAPPVAVFKLTADFRADSDARKVNLGVGAYRTDDSQPWVLPVVKKVEQMIAnDNSLNHEYLPILGLPEFRS 80
Cdd:PTZ00376   1 MDSLFSQVPLGPPDPILGLAAAFKADPSPSKVNLGIGAYRDENGKPYVLESVRKAEKIIA-EKNLDKEYLPIEGLQSFIE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225  81 SASRIALGDDSPAFKEDRVGGVQSLGGTGALRIGAEFLRRWYNGnnntATPIYISSPSWENHNAVFMDAGFKdIRAYRYW 160
Cdd:PTZ00376  80 AAQKLLFGEASYALAEKRIATVQALSGTGALRLGFEFLKRFLPA----GTTVYVSNPTWPNHVNIFKSAGLN-VKEYRYY 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 161 DAAKRGLDLEGFLQDLENAPEFSIFLLHACAHNPTGTDPTPDEWRKIADVMKRRSLFPFFDSAYQGFASGSLDKDAWAVR 240
Cdd:PTZ00376 155 DPKTKGLDFDGMLEDLRTAPNGSVVLLHACAHNPTGVDPTEEQWKEIADVMKRKNLIPFFDMAYQGFASGDLDKDAYAIR 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 241 FFVSQGFELFCAQSFSKNFGLYNERVGNLTVVGKDGDNVARVLSQMEKIVRTTWSNPPSQGARIVATTLNTPELFDEWRD 320
Cdd:PTZ00376 235 LFAERGVEFLVAQSFSKNMGLYGERIGALHIVCANKEEAANVLSQLKLIIRPMYSSPPIHGARIADRILSDPELRAEWLS 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 321 NVKTMAERVLLMRAELKSRLEALKTPGTWNHIVNQIGMFSYTGLNPKQVEYLIKEKHIYLMASGRINMCGLTTKNIDYVA 400
Cdd:PTZ00376 315 ELKEMSGRIQNMRQLLYDELKALGSPGDWEHIINQIGMFSFTGLTKEQVERLIEKYHIYLLDNGRISVAGLTSKNVDYVA 394

                        410
                 ....*....|
gi 147903225 401 QSIYEASTKI 410
Cdd:PTZ00376 395 EAIHDVVRNV 404
 
Name Accession Description Interval E-value
PTZ00376 PTZ00376
aspartate aminotransferase; Provisional
 1-410 0e+00

aspartate aminotransferase; Provisional


Pssm-ID: 240390  Cd Length: 404  Bit Score: 625.80  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225   1 MASIFCSVPQAPPVAVFKLTADFRADSDARKVNLGVGAYRTDDSQPWVLPVVKKVEQMIAnDNSLNHEYLPILGLPEFRS 80
Cdd:PTZ00376   1 MDSLFSQVPLGPPDPILGLAAAFKADPSPSKVNLGIGAYRDENGKPYVLESVRKAEKIIA-EKNLDKEYLPIEGLQSFIE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225  81 SASRIALGDDSPAFKEDRVGGVQSLGGTGALRIGAEFLRRWYNGnnntATPIYISSPSWENHNAVFMDAGFKdIRAYRYW 160
Cdd:PTZ00376  80 AAQKLLFGEASYALAEKRIATVQALSGTGALRLGFEFLKRFLPA----GTTVYVSNPTWPNHVNIFKSAGLN-VKEYRYY 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 161 DAAKRGLDLEGFLQDLENAPEFSIFLLHACAHNPTGTDPTPDEWRKIADVMKRRSLFPFFDSAYQGFASGSLDKDAWAVR 240
Cdd:PTZ00376 155 DPKTKGLDFDGMLEDLRTAPNGSVVLLHACAHNPTGVDPTEEQWKEIADVMKRKNLIPFFDMAYQGFASGDLDKDAYAIR 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 241 FFVSQGFELFCAQSFSKNFGLYNERVGNLTVVGKDGDNVARVLSQMEKIVRTTWSNPPSQGARIVATTLNTPELFDEWRD 320
Cdd:PTZ00376 235 LFAERGVEFLVAQSFSKNMGLYGERIGALHIVCANKEEAANVLSQLKLIIRPMYSSPPIHGARIADRILSDPELRAEWLS 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 321 NVKTMAERVLLMRAELKSRLEALKTPGTWNHIVNQIGMFSYTGLNPKQVEYLIKEKHIYLMASGRINMCGLTTKNIDYVA 400
Cdd:PTZ00376 315 ELKEMSGRIQNMRQLLYDELKALGSPGDWEHIINQIGMFSFTGLTKEQVERLIEKYHIYLLDNGRISVAGLTSKNVDYVA 394

                        410
                 ....*....|
gi 147903225 401 QSIYEASTKI 410
Cdd:PTZ00376 395 EAIHDVVRNV 404
TyrB COG1448
Aspartate/aromatic aminotransferase [Amino acid transport and metabolism]; Aspartate/aromatic ...
 5-403 0e+00

Aspartate/aromatic aminotransferase [Amino acid transport and metabolism]; Aspartate/aromatic aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 441057  Cd Length: 396  Bit Score: 521.19  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225   5 FCSVPQAPPVAVFKLTADFRADSDARKVNLGVGAYRTDDSQPWVLPVVKKVEQMIAnDNSLNHEYLPILGLPEFRSSASR 84
Cdd:COG1448    2 FEHLEAAPGDPILGLMEAFRADPRPNKVNLGVGVYKDEQGRTPVLRAVKAAEQRLL-ETETTKSYLPIEGDAAFNDAVQK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225  85 IALGDDSPAFKEDRVGGVQSLGGTGALRIGAEFLRRWyngnnNTATPIYISSPSWENHNAVFMDAGFKdIRAYRYWDAAK 164
Cdd:COG1448   81 LLFGADSPAVAAGRVATVQTPGGTGALRVGADFLKRA-----FPDATVWVSDPTWPNHRAIFEAAGLE-VKTYPYYDAET 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 165 RGLDLEGFLQDLENAPEFSIFLLHACAHNPTGTDPTPDEWRKIADVMKRRSLFPFFDSAYQGFASGsLDKDAWAVRFFVS 244
Cdd:COG1448  155 GGVDFDGMLADLKQLPAGDVVLLHGCCHNPTGADLTPEQWQEVAELLKERGLIPFLDIAYQGFGDG-LEEDAAGLRLFAE 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 245 QGFELFCAQSFSKNFGLYNERVGNLTVVGKDGDNVARVLSQMEKIVRTTWSNPPSQGARIVATTLNTPELFDEWRDNVKT 324
Cdd:COG1448  234 AGPEFLVASSFSKNFGLYRERVGALSVVAADAEEADRVLSQLKALIRTNYSNPPDHGAAIVATILNDPELRALWEAELAE 313

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 147903225 325 MAERVLLMRAELKSRLEALKTPGTWNHIVNQIGMFSYTGLNPKQVEYLIKEKHIYLMASGRINMCGLTTKNIDYVAQSI 403
Cdd:COG1448  314 MRERIKAMRQQLVDALRAKGPSRDFSFIARQRGMFSYLGLSPEQVDRLREEFGIYMVGSGRINVAGLNESNIDYVAEAI 392
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
31-403 1.04e-93

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 285.35  E-value: 1.04e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225   31 KVNLGVGAYRTDdsqpwVLPVVKKVEQMiANDNSLNHEYLPILGLPEFRSSASRIALgdDSPAFKEDRVGGVQSLGGTGA 110
Cdd:pfam00155   3 KINLGSNEYLGD-----TLPAVAKAEKD-ALAGGTRNLYGPTDGHPELREALAKFLG--RSPVLKLDREAAVVFGSGAGA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225  111 LRIGAEFLRrwyngnNNTATPIYISSPSWENHNAVFMDAGFKdIRAYRYWDAAKRGLDLEGFLQDLENAPefsIFLLHAC 190
Cdd:pfam00155  75 NIEALIFLL------ANPGDAILVPAPTYASYIRIARLAGGE-VVRYPLYDSNDFHLDFDALEAALKEKP---KVVLHTS 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225  191 AHNPTGTDPTPDEWRKIADVMKRRSLFPFFDSAYQGFASGslDKDAWAVRFFVSQGFELFCAQSFSKNFGLYNERVGNLT 270
Cdd:pfam00155 145 PHNPTGTVATLEELEKLLDLAKEHNILLLVDEAYAGFVFG--SPDAVATRALLAEGPNLLVVGSFSKAFGLAGWRVGYIL 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225  271 VvgkdgdnVARVLSQMEKIVRTTWSnpPSQGARIVATTLNTPELFDEWrdnVKTMAERVLLMRAELKSRLEALktpgTWN 350
Cdd:pfam00155 223 G-------NAAVISQLRKLARPFYS--STHLQAAAAAALSDPLLVASE---LEEMRQRIKERRDYLRDGLQAA----GLS 286

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 147903225  351 HIVNQIGMFSYTGLNPKQV----EYLIKEKHIYLMA--------SGRINMCGLTTKNIDYVAQSI 403
Cdd:pfam00155 287 VLPSQAGFFLLTGLDPETAkelaQVLLEEVGVYVTPgsspgvpgWLRITVAGGTEEELEELLEAI 351
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 32-405 5.34e-52

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 177.53  E-value: 5.34e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225  32 VNLGVGAYRTDDSQPWVLPVVKkveqmiANDNSLNHEYLPILGLPEFRSSASRIALGDDSPAFKEDRVggVQSLGGTGAL 111
Cdd:cd00609    1 IDLSIGEPDFPPPPEVLEALAA------AALRAGLLGYYPDPGLPELREAIAEWLGRRGGVDVPPEEI--VVTNGAQEAL 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 112 RIGAEFLRRWyngnnntATPIYISSPSWENHNAVFMDAGFKdIRAYRYWDAAKRGLDLEgfLQDLENAPEFSIFLLHACa 191
Cdd:cd00609   73 SLLLRALLNP-------GDEVLVPDPTYPGYEAAARLAGAE-VVPVPLDEEGGFLLDLE--LLEAAKTPKTKLLYLNNP- 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 192 HNPTGTDPTPDEWRKIADVMKRRSLFPFFDSAYQGFASGSLDKDAWAvrfFVSQGFELFCAQSFSKNFGLYNERVGNLTV 271
Cdd:cd00609  142 NNPTGAVLSEEELEELAELAKKHGILIISDEAYAELVYDGEPPPALA---LLDAYERVIVLRSFSKTFGLPGLRIGYLIA 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 272 VGKdgdnvaRVLSQMEKIVRTTWSNPPSQGARIVATTLNTPElfdewrDNVKTMAERVLLMRAELksrLEALKTPGTWNH 351
Cdd:cd00609  219 PPE------ELLERLKKLLPYTTSGPSTLSQAAAAAALDDGE------EHLEELRERYRRRRDAL---LEALKELGPLVV 283

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 147903225 352 IVNQIGMFSYTGLNP----KQVEYLIKEKHIYLMASG----------RINMCGLtTKNIDYVAQSIYE 405
Cdd:cd00609  284 VKPSGGFFLWLDLPEgddeEFLERLLLEAGVVVRPGSafgeggegfvRLSFATP-EEELEEALERLAE 350
 
Name Accession Description Interval E-value
PTZ00376 PTZ00376
aspartate aminotransferase; Provisional
 1-410 0e+00

aspartate aminotransferase; Provisional


Pssm-ID: 240390  Cd Length: 404  Bit Score: 625.80  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225   1 MASIFCSVPQAPPVAVFKLTADFRADSDARKVNLGVGAYRTDDSQPWVLPVVKKVEQMIAnDNSLNHEYLPILGLPEFRS 80
Cdd:PTZ00376   1 MDSLFSQVPLGPPDPILGLAAAFKADPSPSKVNLGIGAYRDENGKPYVLESVRKAEKIIA-EKNLDKEYLPIEGLQSFIE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225  81 SASRIALGDDSPAFKEDRVGGVQSLGGTGALRIGAEFLRRWYNGnnntATPIYISSPSWENHNAVFMDAGFKdIRAYRYW 160
Cdd:PTZ00376  80 AAQKLLFGEASYALAEKRIATVQALSGTGALRLGFEFLKRFLPA----GTTVYVSNPTWPNHVNIFKSAGLN-VKEYRYY 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 161 DAAKRGLDLEGFLQDLENAPEFSIFLLHACAHNPTGTDPTPDEWRKIADVMKRRSLFPFFDSAYQGFASGSLDKDAWAVR 240
Cdd:PTZ00376 155 DPKTKGLDFDGMLEDLRTAPNGSVVLLHACAHNPTGVDPTEEQWKEIADVMKRKNLIPFFDMAYQGFASGDLDKDAYAIR 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 241 FFVSQGFELFCAQSFSKNFGLYNERVGNLTVVGKDGDNVARVLSQMEKIVRTTWSNPPSQGARIVATTLNTPELFDEWRD 320
Cdd:PTZ00376 235 LFAERGVEFLVAQSFSKNMGLYGERIGALHIVCANKEEAANVLSQLKLIIRPMYSSPPIHGARIADRILSDPELRAEWLS 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 321 NVKTMAERVLLMRAELKSRLEALKTPGTWNHIVNQIGMFSYTGLNPKQVEYLIKEKHIYLMASGRINMCGLTTKNIDYVA 400
Cdd:PTZ00376 315 ELKEMSGRIQNMRQLLYDELKALGSPGDWEHIINQIGMFSFTGLTKEQVERLIEKYHIYLLDNGRISVAGLTSKNVDYVA 394

                        410
                 ....*....|
gi 147903225 401 QSIYEASTKI 410
Cdd:PTZ00376 395 EAIHDVVRNV 404
PLN02397 PLN02397
aspartate transaminase
 1-411 0e+00

aspartate transaminase


Pssm-ID: 215222  Cd Length: 423  Bit Score: 612.35  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225   1 MASIFCSVPQAPPVAVFKLTADFRADSDARKVNLGVGAYRTDDSQPWVLPVVKKVEQMIaNDNSLNHEYLPILGLPEFRS 80
Cdd:PLN02397  20 ASSRFEHVEPAPPDPILGVTEAFLADPSPVKLNLGVGAYRTEEGKPVVLNVVRKAEQRL-LAGSRNKEYLPIEGLAEFNK 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225  81 SASRIALGDDSPAFKEDRVGGVQSLGGTGALRIGAEFLRRWYNGnnntaTPIYISSPSWENHNAVFMDAGFkDIRAYRYW 160
Cdd:PLN02397  99 LSAKLAYGADSPAIKENRVATVQCLSGTGSLRLGAEFLARFYPG-----STIYIPNPTWGNHHNIFRDAGV-PVRTYRYY 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 161 DAAKRGLDLEGFLQDLENAPEFSIFLLHACAHNPTGTDPTPDEWRKIADVMKRRSLFPFFDSAYQGFASGSLDKDAWAVR 240
Cdd:PLN02397 173 DPKTRGLDFDGLLEDLKAAPDGSFVLLHACAHNPTGVDPTPEQWEQISDLIKSKNHLPFFDSAYQGFASGDLDADAQSVR 252

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 241 FFVSQGFELFCAQSFSKNFGLYNERVGNLTVVGKDGDNVARVLSQMEKIVRTTWSNPPSQGARIVATTLNTPELFDEWRD 320
Cdd:PLN02397 253 MFVEDGHEILVAQSYAKNMGLYGERVGALSVVCKSADVAVRVKSQLKLIARPMYSNPPIHGASIVATILGDPELFSEWTK 332

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 321 NVKTMAERVLLMRAELKSRLEALKTPGTWNHIVNQIGMFSYTGLNPKQVEYLIKEKHIYLMASGRINMCGLTTKNIDYVA 400
Cdd:PLN02397 333 ELKGMADRIISMRQKLYDALEARGSPGDWSHITKQIGMFSFTGLNKEQVDRMTKEYHIYMTRDGRISMAGLSSKNVPYLA 412

                        410
                 ....*....|.
gi 147903225 401 QSIYEASTKIQ 411
Cdd:PLN02397 413 DAIHAVVTNAS 423
TyrB COG1448
Aspartate/aromatic aminotransferase [Amino acid transport and metabolism]; Aspartate/aromatic ...
 5-403 0e+00

Aspartate/aromatic aminotransferase [Amino acid transport and metabolism]; Aspartate/aromatic aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 441057  Cd Length: 396  Bit Score: 521.19  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225   5 FCSVPQAPPVAVFKLTADFRADSDARKVNLGVGAYRTDDSQPWVLPVVKKVEQMIAnDNSLNHEYLPILGLPEFRSSASR 84
Cdd:COG1448    2 FEHLEAAPGDPILGLMEAFRADPRPNKVNLGVGVYKDEQGRTPVLRAVKAAEQRLL-ETETTKSYLPIEGDAAFNDAVQK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225  85 IALGDDSPAFKEDRVGGVQSLGGTGALRIGAEFLRRWyngnnNTATPIYISSPSWENHNAVFMDAGFKdIRAYRYWDAAK 164
Cdd:COG1448   81 LLFGADSPAVAAGRVATVQTPGGTGALRVGADFLKRA-----FPDATVWVSDPTWPNHRAIFEAAGLE-VKTYPYYDAET 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 165 RGLDLEGFLQDLENAPEFSIFLLHACAHNPTGTDPTPDEWRKIADVMKRRSLFPFFDSAYQGFASGsLDKDAWAVRFFVS 244
Cdd:COG1448  155 GGVDFDGMLADLKQLPAGDVVLLHGCCHNPTGADLTPEQWQEVAELLKERGLIPFLDIAYQGFGDG-LEEDAAGLRLFAE 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 245 QGFELFCAQSFSKNFGLYNERVGNLTVVGKDGDNVARVLSQMEKIVRTTWSNPPSQGARIVATTLNTPELFDEWRDNVKT 324
Cdd:COG1448  234 AGPEFLVASSFSKNFGLYRERVGALSVVAADAEEADRVLSQLKALIRTNYSNPPDHGAAIVATILNDPELRALWEAELAE 313

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 147903225 325 MAERVLLMRAELKSRLEALKTPGTWNHIVNQIGMFSYTGLNPKQVEYLIKEKHIYLMASGRINMCGLTTKNIDYVAQSI 403
Cdd:COG1448  314 MRERIKAMRQQLVDALRAKGPSRDFSFIARQRGMFSYLGLSPEQVDRLREEFGIYMVGSGRINVAGLNESNIDYVAEAI 392
PRK09257 PRK09257
aromatic amino acid transaminase;
4-403 0e+00

aromatic amino acid transaminase;


Pssm-ID: 181731  Cd Length: 396  Bit Score: 516.99  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225   4 IFCSVPQAPPVAVFKLTADFRADSDARKVNLGVGAYRTDDSQPWVLPVVKKVEQMIAnDNSLNHEYLPILGLPEFRSSAS 83
Cdd:PRK09257   1 MFEHLEAAPADPILGLMEAFRADPRPDKVNLGVGVYKDEQGRTPVLRAVKKAEARLL-ETETTKNYLPIEGLAAYRQAVQ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225  84 RIALGDDSPAFKEDRVGGVQSLGGTGALRIGAEFLRRWyngnnNTATPIYISSPSWENHNAVFMDAGFKdIRAYRYWDAA 163
Cdd:PRK09257  80 ELLFGADSPALAAGRVATVQTPGGTGALRVGADFLKRA-----FPDAKVWVSDPTWPNHRAIFEAAGLE-VKTYPYYDAA 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 164 KRGLDLEGFLQDLENAPEFSIFLLHACAHNPTGTDPTPDEWRKIADVMKRRSLFPFFDSAYQGFASGsLDKDAWAVRFFV 243
Cdd:PRK09257 154 TKGLDFDAMLADLSQAPAGDVVLLHGCCHNPTGADLTPEQWDELAELLKERGLIPFLDIAYQGFGDG-LEEDAYGLRAFA 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 244 SQGFELFCAQSFSKNFGLYNERVGNLTVVGKDGDNVARVLSQMEKIVRTTWSNPPSQGARIVATTLNTPELFDEWRDNVK 323
Cdd:PRK09257 233 AAGLELLVASSFSKNFGLYGERVGALSVVAEDAEEADRVLSQLKATIRTNYSNPPAHGAAIVATILNDPELRAEWEAELE 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 324 TMAERVLLMRAELKSRLEALKTPGTWNHIVNQIGMFSYTGLNPKQVEYLIKEKHIYLMASGRINMCGLTTKNIDYVAQSI 403
Cdd:PRK09257 313 EMRERIKAMRQLLVEALKAKGPSRDFDFIARQRGMFSYSGLTPEQVDRLREEFGVYAVGSGRINVAGLNESNIDYVAEAI 392
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
31-403 1.04e-93

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 285.35  E-value: 1.04e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225   31 KVNLGVGAYRTDdsqpwVLPVVKKVEQMiANDNSLNHEYLPILGLPEFRSSASRIALgdDSPAFKEDRVGGVQSLGGTGA 110
Cdd:pfam00155   3 KINLGSNEYLGD-----TLPAVAKAEKD-ALAGGTRNLYGPTDGHPELREALAKFLG--RSPVLKLDREAAVVFGSGAGA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225  111 LRIGAEFLRrwyngnNNTATPIYISSPSWENHNAVFMDAGFKdIRAYRYWDAAKRGLDLEGFLQDLENAPefsIFLLHAC 190
Cdd:pfam00155  75 NIEALIFLL------ANPGDAILVPAPTYASYIRIARLAGGE-VVRYPLYDSNDFHLDFDALEAALKEKP---KVVLHTS 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225  191 AHNPTGTDPTPDEWRKIADVMKRRSLFPFFDSAYQGFASGslDKDAWAVRFFVSQGFELFCAQSFSKNFGLYNERVGNLT 270
Cdd:pfam00155 145 PHNPTGTVATLEELEKLLDLAKEHNILLLVDEAYAGFVFG--SPDAVATRALLAEGPNLLVVGSFSKAFGLAGWRVGYIL 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225  271 VvgkdgdnVARVLSQMEKIVRTTWSnpPSQGARIVATTLNTPELFDEWrdnVKTMAERVLLMRAELKSRLEALktpgTWN 350
Cdd:pfam00155 223 G-------NAAVISQLRKLARPFYS--STHLQAAAAAALSDPLLVASE---LEEMRQRIKERRDYLRDGLQAA----GLS 286

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 147903225  351 HIVNQIGMFSYTGLNPKQV----EYLIKEKHIYLMA--------SGRINMCGLTTKNIDYVAQSI 403
Cdd:pfam00155 287 VLPSQAGFFLLTGLDPETAkelaQVLLEEVGVYVTPgsspgvpgWLRITVAGGTEEELEELLEAI 351
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 32-405 5.34e-52

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 177.53  E-value: 5.34e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225  32 VNLGVGAYRTDDSQPWVLPVVKkveqmiANDNSLNHEYLPILGLPEFRSSASRIALGDDSPAFKEDRVggVQSLGGTGAL 111
Cdd:cd00609    1 IDLSIGEPDFPPPPEVLEALAA------AALRAGLLGYYPDPGLPELREAIAEWLGRRGGVDVPPEEI--VVTNGAQEAL 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 112 RIGAEFLRRWyngnnntATPIYISSPSWENHNAVFMDAGFKdIRAYRYWDAAKRGLDLEgfLQDLENAPEFSIFLLHACa 191
Cdd:cd00609   73 SLLLRALLNP-------GDEVLVPDPTYPGYEAAARLAGAE-VVPVPLDEEGGFLLDLE--LLEAAKTPKTKLLYLNNP- 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 192 HNPTGTDPTPDEWRKIADVMKRRSLFPFFDSAYQGFASGSLDKDAWAvrfFVSQGFELFCAQSFSKNFGLYNERVGNLTV 271
Cdd:cd00609  142 NNPTGAVLSEEELEELAELAKKHGILIISDEAYAELVYDGEPPPALA---LLDAYERVIVLRSFSKTFGLPGLRIGYLIA 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 272 VGKdgdnvaRVLSQMEKIVRTTWSNPPSQGARIVATTLNTPElfdewrDNVKTMAERVLLMRAELksrLEALKTPGTWNH 351
Cdd:cd00609  219 PPE------ELLERLKKLLPYTTSGPSTLSQAAAAAALDDGE------EHLEELRERYRRRRDAL---LEALKELGPLVV 283

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 147903225 352 IVNQIGMFSYTGLNP----KQVEYLIKEKHIYLMASG----------RINMCGLtTKNIDYVAQSIYE 405
Cdd:cd00609  284 VKPSGGFFLWLDLPEgddeEFLERLLLEAGVVVRPGSafgeggegfvRLSFATP-EEELEEALERLAE 350
AAT_I cd01494
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ...
 94-271 4.99e-23

Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).


Pssm-ID: 99742 [Multi-domain]  Cd Length: 170  Bit Score: 94.76  E-value: 4.99e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225  94 FKEDRVGGVQSLGGTGALRIGAEFLRRWyngnnntATPIYISSPSWENHNAVFMDAGFKDIRAYRYWDAAKRGLDLeGFL 173
Cdd:cd01494   13 LQPGNDKAVFVPSGTGANEAALLALLGP-------GDEVIVDANGHGSRYWVAAELAGAKPVPVPVDDAGYGGLDV-AIL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 174 QDLENAPEFSIFLLHACAHNPTGTDPTpdewRKIADVMKRRSLFPFFDSAYQGFASGsldkdawAVRFFVSQGFELFCAQ 253
Cdd:cd01494   85 EELKAKPNVALIVITPNTTSGGVLVPL----KEIRKIAKEYGILLLVDAASAGGASP-------APGVLIPEGGADVVTF 153

                        170
                 ....*....|....*...
gi 147903225 254 SFSKNFGLynERVGNLTV 271
Cdd:cd01494  154 SLHKNLGG--EGGGVVIV 169
PRK08637 PRK08637
hypothetical protein; Provisional
 29-406 7.59e-09

hypothetical protein; Provisional


Pssm-ID: 181512  Cd Length: 388  Bit Score: 56.89  E-value: 7.59e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225  29 ARKVNLGVGAyRTDDSQPWVLPVVKKVEQMIANDNSLnhEYLPILGLPEFRSsASRIALGDDSPAFKEDRVGG-VQSLGG 107
Cdd:PRK08637   3 ATKYNATIGM-ATEKGGPMYLSSLQDLLNDLTPDEIF--PYAPPQGIPELRD-LWQEKMLRENPSLSGKKMSLpIVTNAL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 108 TGALRIGAE-FLrrwyngnnNTATPIYISSPSWENHNAVFMDAGFKDIRAYRYWDAAKrGLDLEGFLQDLENAPEFS-IF 185
Cdd:PRK08637  79 THGLSLVADlFV--------DQGDTVLLPDHNWGNYKLTFNTRRGAEIVTYPIFDEDG-GFDTDALKEALQAAYNKGkVI 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 186 LLHACAHNPTGTDPTPDEWRKIADVMK-----RRSLFPFFDSAYQGF-----ASGSL-------DKDAWAVR-------F 241
Cdd:PRK08637 150 VILNFPNNPTGYTPTEKEATAIVEAIKeladaGTKVVAVVDDAYFGLfyedsYKESLfaalanlHSNILAVKldgatkeE 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 242 FVsqgfelfcaqsfsknFGLyneRVGNLTVVGKDGDNvARVLSQMEK----IVRTTWSNPPSQGARIVATTLNTPELFDE 317
Cdd:PRK08637 230 FV---------------WGF---RVGFITFGTKAGSS-QTVKEALEKkvkgLIRSNISNGPHPSQSAVLRALNSPEFDKE 290

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 318 WRDNVKTMAERVLlmraELKSRLEALKTPGTWNHIVNQIGMFsyTGLNPKQVE------YLIKEKHIYLMASG----RIN 387
Cdd:PRK08637 291 KQEKFQILKERYE----KTKEVLYDGKYDDAWQAYPFNSGYF--MCLKLKGVDaeelrvHLLEKYGIGTIALNetdlRIA 364

                        410
                 ....*....|....*....
gi 147903225 388 MCGLTTKNIDYVAQSIYEA 406
Cdd:PRK08637 365 FSCVEEEDIPELFDSIYKA 383
AspB COG0436
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ...
 192-378 2.01e-07

Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 440205 [Multi-domain]  Cd Length: 387  Bit Score: 52.44  E-value: 2.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 192 HNPTGTDPTPDEWRKIADVMKRRSLFPFFDSAYQGFASGS------LDKDAWAVRffvsqGFELFcaqSFSKNFGLYNER 265
Cdd:COG0436  173 NNPTGAVYSREELEALAELAREHDLLVISDEIYEELVYDGaehvsiLSLPGLKDR-----TIVIN---SFSKSYAMTGWR 244

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 266 VGnlTVVGKdgdnvARVLSQMEKIVRTTWSNPPSQGARIVATTLNTPElfDEWRDNVKTMAERVLLMRAELKS-RLEALK 344
Cdd:COG0436  245 IG--YAVGP-----PELIAALLKLQSNLTSCAPTPAQYAAAAALEGPQ--DYVEEMRAEYRRRRDLLVEGLNEiGLSVVK 315

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 147903225 345 TPGTWNHIVNqigmFSYTGLNPKQ-VEYLIKEKHI 378
Cdd:COG0436  316 PEGAFYLFAD----VPELGLDSEEfAERLLEEAGV 346
PRK07337 PRK07337
pyridoxal phosphate-dependent aminotransferase;
187-271 9.76e-05

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180937  Cd Length: 388  Bit Score: 44.28  E-value: 9.76e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 187 LHACAHNPTGTDPTPDEWRKIADVMKRRSLFPFFDSAYQGfasgsLDKDAwAVRFFVSQGFELFCAQSFSKNFGLYNERV 266
Cdd:PRK07337 168 LLASPSNPTGTSIAPDELRRIVEAVRARGGFTIVDEIYQG-----LSYDA-APVSALSLGDDVITINSFSKYFNMTGWRL 241


                 ....*
gi 147903225 267 GNLTV 271
Cdd:PRK07337 242 GWLVV 246
PRK07550 PRK07550
aminotransferase;
193-336 1.27e-03

aminotransferase;


Pssm-ID: 181026 [Multi-domain]  Cd Length: 386  Bit Score: 40.71  E-value: 1.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 193 NPTGTDPTPDEWRKIADVMKRRSLFPFFDSAYQGFASGS------LDKDAWavrffvsqGFELFCAQSFSKNFGLYNERV 266
Cdd:PRK07550 174 NPTGVVYPPELLHELYDLARRHGIALILDETYRDFDSGGgaphdlFADPDW--------DDTLVHLYSFSKSYALTGHRV 245

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 147903225 267 GNLTVVGKdgdnvarVLSQMEKIVRTTWSNPPSQGARIVATTLntpELFDEWRD-NVKTMAERVLLMRAEL 336
Cdd:PRK07550 246 GAVVASPA-------RIAEIEKFMDTVAICAPRIGQIAVAWGL---PNLADWRAgNRAEIARRRDAFRAVF 306
PRK08960 PRK08960
pyridoxal phosphate-dependent aminotransferase;
158-319 1.86e-03

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181595  Cd Length: 387  Bit Score: 40.04  E-value: 1.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 158 RYWDAAKRGLdlegflqdlenapefsiflLHACAHNPTGTDPTPDEWRKIADVMKRRSLFPFFDSAYQGFASGSldkDAW 237
Cdd:PRK08960 160 RHWNADTVGA-------------------LVASPANPTGTLLSRDELAALSQALRARGGHLVVDEIYHGLTYGV---DAA 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 238 AVrffVSQGFELFCAQSFSKNFGLYNERVGNLTVvgkdgdnVARVLSQMEKIVRTTWSNPPS--QGARIVATTLNTPELF 315
Cdd:PRK08960 218 SV---LEVDDDAFVLNSFSKYFGMTGWRLGWLVA-------PPAAVPELEKLAQNLYISASTpaQHAALACFEPETLAIL 287


                 ....
gi 147903225 316 DEWR 319
Cdd:PRK08960 288 EARR 291
PRK06225 PRK06225
pyridoxal phosphate-dependent aminotransferase;
193-376 3.00e-03

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235749 [Multi-domain]  Cd Length: 380  Bit Score: 39.35  E-value: 3.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 193 NPTGTDPTPDEWRKIADVMKRRSLFPFFDSAYQGFAsgslDKDAWAVRFFVSQGFELFcaqSFSKNFGLYNERVGnlTVV 272
Cdd:PRK06225 168 NPLGSSYTEEEIKEFAEIARDNDAFLLHDCTYRDFA----REHTLAAEYAPEHTVTSY---SFSKIFGMAGLRIG--AVV 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147903225 273 GKdgdnvARVLSQMEKIVRTTW-SNPPSQGARIVATTLNtpelfDEWRDNVKTMAERVLLMRAELKSRLEALKTPGTWNH 351
Cdd:PRK06225 239 AT-----PDLIEVVKSIVINDLgTNVIAQEAAIAGLKVK-----DEWIDRIRRTTFKNQKLIKEAVDEIEGVFLPVYPSH 308

                        170       180
                 ....*....|....*....|....*..
gi 147903225 352 iVNQIGM-FSYTGLNPKQ-VEYLIKEK 376
Cdd:PRK06225 309 -GNMMVIdISEAGIDPEDlVEYLLERK 334
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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