U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    NSP2 nitrile specifier protein 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817869, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    NSP2
    Official Full Name
    nitrile specifier protein 2
    Primary source
    TAIR:AT2G33070
    Locus tag
    AT2G33070
    See related
    Araport:AT2G33070
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATNSP2; F25I18.19; F25I18_19; nitrile specifier protein 2; NITRILE-SPECIFIER PROTEIN 2
    Summary
    Encodes a nitrile-specifier protein NSP2. NSP2 is one out of five (At3g16400/NSP1, At2g33070/NSP2, At3g16390/NSP3, At3g16410/NSP4 and At5g48180/NSP5) A. thaliana epithiospecifier protein (ESP) homologues that promote simple nitrile, but not epithionitrile or thiocyanate formation.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See NSP2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (14028282..14031164, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene receptor like protein 26 Neighboring gene receptor like protein 27 Neighboring gene receptor like protein 28 Neighboring gene Transcription elongation factor (TFIIS) family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Glucosinolate Content in Dormant and Germinating Arabidopsis thaliana Seeds Is Affected by Non-Functional Alleles of Classical Myrosinase and Nitrile-Specifier Protein Genes. Meier K, et al. Front Plant Sci, 2019. PMID 31850033, Free PMC Article
    2. The genetic basis of constitutive and herbivore-induced ESP-independent nitrile formation in Arabidopsis. Burow M, et al. Plant Physiol, 2009 Jan. PMID 18987211, Free PMC Article
    3. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtNSP2 is one out of five A. thaliana ESP homologues that promote simple nitrile, but not epithionitrile or thiocyanate formation. [AtNSP2]
      Title: The genetic basis of constitutive and herbivore-induced ESP-independent nitrile formation in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    NM_001036391.1
    NM_001202734.1
    NM_128867.3

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    involved_in embryo development ending in seed dormancy IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within glucosinolate catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within glucosinolate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within nitrile biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within seed dormancy process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within seed germination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in endoplasmic reticulum HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    nitrile specifier protein 2
    NP_001031468.1
    • nitrile specifier protein 2 (NSP2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: glucosinolate catabolic process, nitrile biosynthetic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: leaf apex, hypocotyl, root, flower, seed; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Galactose oxidase/kelch, beta-propeller (InterPro:IPR011043), Kelch repeat type 1 (InterPro:IPR006652), Mannose-binding lectin (InterPro:IPR001229), Myrosinase-binding related, jacalin-like lectin (InterPro:IPR017388), Kelch-type beta propeller (InterPro:IPR015915); BEST Arabidopsis thaliana protein match is: nitrile specifier protein 1 (TAIR:AT3G16400.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_001189663.1
    • nitrile specifier protein 2 (NSP2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: glucosinolate catabolic process, nitrile biosynthetic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: leaf apex, hypocotyl, root, flower; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Kelch repeat type 1 (InterPro:IPR006652), Galactose oxidase/kelch, beta-propeller (InterPro:IPR011043), Mannose-binding lectin (InterPro:IPR001229), Kelch-type beta propeller (InterPro:IPR015915); BEST Arabidopsis thaliana protein match is: nitrile specifier protein 1 (TAIR:AT3G16400.2).
    NP_180866.1
    • nitrile specifier protein 2 (NSP2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: glucosinolate catabolic process, nitrile biosynthetic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: leaf apex, hypocotyl, root, flower, seed; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Galactose oxidase/kelch, beta-propeller (InterPro:IPR011043), Kelch repeat type 1 (InterPro:IPR006652), Mannose-binding lectin (InterPro:IPR001229), Myrosinase-binding related, jacalin-like lectin (InterPro:IPR017388), Kelch-type beta propeller (InterPro:IPR015915); BEST Arabidopsis thaliana protein match is: nitrile specifier protein 1 (TAIR:AT3G16400.2); Has 13143 Blast hits to 7111 proteins in 397 species: Archae - 8; Bacteria - 421; Metazoa - 7625; Fungi - 714; Plants - 2778; Viruses - 30; Other Eukaryotes - 1567 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      14028282..14031164 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001202734.1 → NP_001189663.1  nitrile specifier protein 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189663.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VP47
      Conserved Domains (2) summary
      PLN02193
      Location:1 → 473
      PLN02193; nitrile-specifier protein
      sd00038
      Location:169 → 220
      Kelch; KELCH repeat [structural motif]

    2. NM_001036391.1 → NP_001031468.1  nitrile specifier protein 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031468.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IUU4, O49326
      UniProtKB/TrEMBL
      A0A178VP47, A0A5S9X3R0, A0A654F904
      Conserved Domains (2) summary
      PLN02193
      Location:1 → 471
      PLN02193; nitrile-specifier protein
      sd00038
      Location:167 → 218
      Kelch; KELCH repeat [structural motif]

    3. NM_128867.3 → NP_180866.1  nitrile specifier protein 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180866.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IUU4, O49326
      UniProtKB/TrEMBL
      A0A178VP47, A0A5S9X3R0, A0A654F904
      Conserved Domains (2) summary
      PLN02193
      Location:1 → 471
      PLN02193; nitrile-specifier protein
      sd00038
      Location:167 → 218
      Kelch; KELCH repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O49326.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.