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    TIP5;1 tonoplast intrinsic protein 5;1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823898, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TIP5;1
    Official Full Name
    tonoplast intrinsic protein 5;1
    Primary source
    TAIR:AT3G47440
    Locus tag
    AT3G47440
    See related
    Araport:AT3G47440
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    tonoplast intrinsic protein 5;1
    Summary
    Encodes AtTIP5;1, functions as water and urea channels in pollen. Target promoter of the male germline-specific transcription factor DUO1.
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    Genomic context

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    See TIP5;1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (17481996..17483158)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene putative glycerol-3-phosphate transporter 1 Neighboring gene peroxin 11B Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene Structural maintenance of chromosomes (SMC) family protein Neighboring gene light-harvesting chlorophyll-protein complex I subunit A4 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TIP5;1 is an aquaporin specifically targeted to pollen mitochondria and is probably involved in nitrogen remobilization in Arabidopsis thaliana. Soto G, et al. Plant J, 2010 Dec. PMID 21143683
    2. Vegetative and sperm cell-specific aquaporins of Arabidopsis highlight the vacuolar equipment of pollen and contribute to plant reproduction. Wudick MM, et al. Plant Physiol, 2014 Apr. PMID 24492334, Free PMC Article
    3. AtTIP1;3 and AtTIP5;1, the only highly expressed Arabidopsis pollen-specific aquaporins, transport water and urea. Soto G, et al. FEBS Lett, 2008 Dec 10. PMID 19022253
    4. The R2R3 MYB transcription factor DUO1 activates a male germline-specific regulon essential for sperm cell differentiation in Arabidopsis. Borg M, et al. Plant Cell, 2011 Feb. PMID 21285328, Free PMC Article
    5. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtTIP1;3 and AtTIP5;1 are specific for the vacuoles of the vegetative and sperm cells, respectively.
      Title: Vegetative and sperm cell-specific aquaporins of Arabidopsis highlight the vacuolar equipment of pollen and contribute to plant reproduction.
    2. TIP5;1 is localized to pollen mitochondria and is probably involved in pollen nitrogen recycling.
      Title: TIP5;1 is an aquaporin specifically targeted to pollen mitochondria and is probably involved in nitrogen remobilization in Arabidopsis thaliana.
    3. These results suggest a function for AtTIP1;3 and AtTIP5;1 as specific water and urea channels in Arabidopsis pollen.
      Title: AtTIP1;3 and AtTIP5;1, the only highly expressed Arabidopsis pollen-specific aquaporins, transport water and urea.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_114612.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables urea transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables water channel activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables water channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within pollen sperm cell differentiation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within urea transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in pollen tube IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tonoplast intrinsic protein 5;1
    NP_190328.1
    • tonoplast intrinsic protein 5;1 (TIP5;1); FUNCTIONS IN: water channel activity, urea transmembrane transporter activity; INVOLVED IN: transport, urea transport; LOCATED IN: membrane; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, C globular stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: delta tonoplast integral protein (TAIR:AT3G16240.1); Has 9883 Blast hits to 9870 proteins in 2054 species: Archae - 82; Bacteria - 4603; Metazoa - 1430; Fungi - 328; Plants - 2424; Viruses - 0; Other Eukaryotes - 1016 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      17481996..17483158
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114612.4 → NP_190328.1  tonoplast intrinsic protein 5;1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190328.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9STX9
      UniProtKB/TrEMBL
      A0A178VL26, A0A5S9XIM9, A0A654FI99
      Conserved Domains (1) summary
      PLN00167
      Location:1 → 256
      PLN00167; aquaporin TIP5; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9STX9.1

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