CRY1 cryptochrome 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: CRY1
Official Full Name: cryptochrome 1
Primary source: TAIR:AT4G08920
Locus tag: AT4G08920
See related: Araport:AT4G08920
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATCRY1; BLU1; BLUE LIGHT UNINHIBITED 1; cryptochrome 1; CRYPTOCHROME 1 APOPROTEIN (BLUE LIGHT PHOTORECEPTOR; ELONGATED HYPOCOTYL 4; HY4; OOP2; OUT OF PHASE 2; T3H13.14; T3H13_14
Summary: Encodes CRY1, a flavin-type blue-light photoreceptor with ATP binding and autophosphorylation activity. Functions in perception of blue / green ratio of light. The photoreceptor may be involved in electron transport. Mutant phenotype displays a blue light-dependent inhibition of hypocotyl elongation. Photoreceptor activity requires light-induced homodimerisation of the N-terminal CNT1 domains of CRY1. Involved in blue-light induced stomatal opening. The C-terminal domain of the protein undergoes a light dependent conformational change. Also involved in response to circadian rhythm. Mutants exhibit long hypocotyl under blue light and are out of phase in their response to circadian rhythm. CRY1 is present in the nucleus and cytoplasm. Different subcellular pools of CRY1 have different functions during photomorphogenesis of Arabidopsis seedlings.
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Genomic context

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See CRY1 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 4

Sequence:: Chromosome: 4; NC_003075.7 (5723651..5727268)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Importance of Polarizable Embedding for Absorption Spectrum Calculations of Arabidopsis thaliana Cryptochrome 1.
Title: Importance of Polarizable Embedding for Absorption Spectrum Calculations of Arabidopsis thaliana Cryptochrome 1.
UV RESISTANCE LOCUS 8-Mediated UV-B Response Is Required Alongside CRYPTOCHROME 1 for Plant Survival in Sunlight under Field Conditions.
Title: UV RESISTANCE LOCUS 8-Mediated UV-B Response Is Required Alongside CRYPTOCHROME 1 for Plant Survival in Sunlight under Field Conditions.
The blue light receptor CRY1 interacts with FIP37 to promote N[6] -methyladenosine RNA modification and photomorphogenesis in Arabidopsis.
Title: The blue light receptor CRY1 interacts with FIP37 to promote N(6) -methyladenosine RNA modification and photomorphogenesis in Arabidopsis.
Arabidopsis cryptochrome 1 promotes stomatal development through repression of AGB1 inhibition of SPEECHLESS DNA-binding activity.
Title: Arabidopsis cryptochrome 1 promotes stomatal development through repression of AGB1 inhibition of SPEECHLESS DNA-binding activity.
Gibberellin signaling turns blue.
Title: Gibberellin signaling turns blue.
Arabidopsis cryptochrome 1 controls photomorphogenesis through regulation of H2A.Z deposition.
Title: Arabidopsis cryptochrome 1 controls photomorphogenesis through regulation of H2A.Z deposition.
Different response modes and cooperation modulations of blue-light receptors in photomorphogenesis.
Title: Different response modes and cooperation modulations of blue-light receptors in photomorphogenesis.
Photoexcited CRY1 and phyB interact directly with ARF6 and ARF8 to regulate their DNA-binding activity and auxin-induced hypocotyl elongation in Arabidopsis.
Title: Photoexcited CRY1 and phyB interact directly with ARF6 and ARF8 to regulate their DNA-binding activity and auxin-induced hypocotyl elongation in Arabidopsis.
a novel CRY1-BIN2-BZR1 regulatory module that mediates crosstalk between blue light and BR signaling to coordinate plant growth in Arabidopsis
Title: The Blue-Light Receptor CRY1 Interacts with BZR1 and BIN2 to Modulate the Phosphorylation and Nuclear Function of BZR1 in Repressing BR Signaling in Arabidopsis.
results suggest that HBI1 acts as a new CRY1-interacting protein and that the signaling mechanism of CRY1 involves repression of HBI1 transcriptional activity by direct CRY1-HBI1 interaction
Title: CRY1 interacts directly with HBI1 to regulate its transcriptional activity and photomorphogenesis in Arabidopsis.

Submit: New GeneRIF Correction See all GeneRIFs (51)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_116961.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables ATP binding	IDA Inferred from Direct Assay more info	PubMed
enables FAD binding	IDA Inferred from Direct Assay more info	PubMed
enables blue light photoreceptor activity	IDA Inferred from Direct Assay more info	PubMed
enables blue light photoreceptor activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein homodimerization activity	IPI Inferred from Physical Interaction more info	PubMed
enables protein kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables protein-RNA adaptor activity	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within anthocyanin-containing compound metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in anthocyanin-containing compound metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in auxin transport	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within blue light signaling pathway	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within circadian regulation of calcium ion oscillation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in circadian rhythm	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within circadian rhythm	NAS Non-traceable Author Statement more info
acts_upstream_of_or_within detection of light stimulus	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in flavin adenine dinucleotide metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in flavin adenine dinucleotide metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in flavin adenine dinucleotide metabolic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of lateral root development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within photomorphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in photoprotection	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within phototropism	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in phototropism	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in plant organ development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of anion channel activity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of defense response to bacterium	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of shade avoidance	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of systemic acquired resistance	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within protein autophosphorylation	IDA Inferred from Direct Assay more info	PubMed
involved_in protein autophosphorylation	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of circadian rhythm	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of gene expression	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of hydrogen peroxide metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of leaf morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of meristem growth	IGI Inferred from Genetic Interaction more info	PubMed
involved_in regulation of reactive oxygen species metabolic process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within regulation of secondary cell wall biogenesis	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within regulation of unidimensional cell growth	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to absence of light	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to blue light	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within response to blue light	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to blue light	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to blue light	NAS Non-traceable Author Statement more info
involved_in response to far red light	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to high light intensity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to light stimulus	IDA Inferred from Direct Assay more info	PubMed
involved_in response to light stimulus	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to light stimulus	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to low fluence blue light stimulus by blue low-fluence system	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to low fluence blue light stimulus by blue low-fluence system	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to magnetism	IDA Inferred from Direct Assay more info	PubMed
involved_in response to magnetism	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to red light	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to strigolactone	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to temperature stimulus	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to water deprivation	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within singlet oxygen-mediated programmed cell death	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within stomatal movement	IGI Inferred from Genetic Interaction more info	PubMed
involved_in stomatal movement	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	HDA more info	PubMed
located_in nuclear body	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	HDA more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: cryptochrome 1

NP_567341.1

cryptochrome 1 (CRY1); CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Cryptochrome/DNA photolyase, class 1 conserved site, C-terminal (InterPro:IPR018394), DNA photolyase, N-terminal (InterPro:IPR006050), Cryptochrome C-terminal (InterPro:IPR020978), DNA photolyase, FAD-binding/Cryptochrome, C-terminal (InterPro:IPR005101), Cryptochrome, plant (InterPro:IPR014134), Cryptochrome/DNA photolyase, class 1 (InterPro:IPR002081); BEST Arabidopsis thaliana protein match is: cryptochrome 2 (TAIR:AT1G04400.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

5723651..5727268

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_116961.5 → NP_567341.1 cryptochrome 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_567341.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q43125, Q43126, Q8L7Y1, Q9ASZ2, Q9M0S9, Q9ZPF0

UniProtKB/TrEMBL

A0A7G2EVQ3

Conserved Domains (2) summary

TIGR02766
Location:15 → 489

crypt_chrom_pln; cryptochrome, plant family

pfam12546
Location:519 → 622

Cryptochrome_C; Blue/Ultraviolet sensing protein C terminal