U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    NRT1.5 nitrate transporter 1.5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 840139, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    NRT1.5
    Official Full Name
    nitrate transporter 1.5
    Primary source
    TAIR:AT1G32450
    Locus tag
    AT1G32450
    See related
    Araport:AT1G32450
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtNPF7.3; F5D14.23; F5D14_23; nitrate transporter 1.5; NPF7.3; NRT1/ PTR family 7.3
    Summary
    Transmembrane nitrate transporter. Involved in xylem transport of nitrate from root to shoot. Induced in response to nitrate. Not involved in nitrate uptake. expressed in root pericycle cells.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See NRT1.5 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (11715147..11719988, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene F-box and associated interaction domains-containing protein Neighboring gene F-box and associated interaction domains-containing protein Neighboring gene plastidial pyruvate kinase 3 Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Single hybrid motif superfamily protein Neighboring gene isocitrate dehydrogenase IV

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Nitrogen form-mediated ethylene signal regulates root-to-shoot K(+) translocation via NRT1.5. Chen H, et al. Plant Cell Environ, 2021 Dec. PMID 34505300
    2. The Arabidopsis NRT1/PTR FAMILY protein NPF7.3/NRT1.5 is an indole-3-butyric acid transporter involved in root gravitropism. Watanabe S, et al. Proc Natl Acad Sci U S A, 2020 Dec 8. PMID 33219124, Free PMC Article
    3. Nitrate transporter NPF7.3/NRT1.5 plays an essential role in regulating phosphate deficiency responses in Arabidopsis. Cui YN, et al. Biochem Biophys Res Commun, 2019 Jan 1. PMID 30497780
    4. NRT1.5/NPF7.3 Functions as a Proton-Coupled H(+)/K(+) Antiporter for K(+) Loading into the Xylem in Arabidopsis. Li H, et al. Plant Cell, 2017 Aug. PMID 28739644, Free PMC Article
    5. The Arabidopsis nitrate transporter NPF7.3/NRT1.5 is involved in lateral root development under potassium deprivation. Zheng Y, et al. Plant Signal Behav, 2016 May 3. PMID 27089248, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Nitrogen form-mediated ethylene signal regulates root-to-shoot K(+) translocation via NRT1.5.
      Title: Nitrogen form-mediated ethylene signal regulates root-to-shoot K(+) translocation via NRT1.5.
    2. The Arabidopsis NRT1/PTR FAMILY protein NPF7.3/NRT1.5 is an indole-3-butyric acid transporter involved in root gravitropism.
      Title: The Arabidopsis NRT1/PTR FAMILY protein NPF7.3/NRT1.5 is an indole-3-butyric acid transporter involved in root gravitropism.
    3. These data demonstrate that MYB59 responds to low K(+) (LK) stress and directs root-to-shoot K(+)/NO3 (-) transport by regulating the expression of NPF7.3 in Arabidopsis roots.
      Title: The Transcription Factor MYB59 Regulates K(+)/NO(3) (-) Translocation in the Arabidopsis Response to Low K(+) Stress.
    4. The NPF7.3/NRT1.5 is an important component in the regulation of phosphate deficiency responses in Arabidopsis.
      Title: Nitrate transporter NPF7.3/NRT1.5 plays an essential role in regulating phosphate deficiency responses in Arabidopsis.
    5. This study reveals that NRT1.5 plays a crucial role in K(+) translocation from root to shoot and is also involved in the coordination of potassium/nitrates distribution in plants.
      Title: NRT1.5/NPF7.3 Functions as a Proton-Coupled H(+)/K(+) Antiporter for K(+) Loading into the Xylem in Arabidopsis.
    6. a possible involvement of NPF7.3/NRT1.5 in auxin homeostasis in roots under potassium deprivation, is reported.
      Title: The Arabidopsis nitrate transporter NPF7.3/NRT1.5 is involved in lateral root development under potassium deprivation.
    7. NRT1.5 likely perceives nitrate starvation-derived signals to prevent leaf senescence by facilitating foliar potassium accumulation
      Title: Arabidopsis NRT1.5 Mediates the Suppression of Nitrate Starvation-Induced Leaf Senescence by Modulating Foliar Potassium Level.
    8. Data show that nutritional conditions as a critical factor for the joint activity of Arabidopsis proteins SKOR and NPF7.3/NRT1.5 for shoot potassium (K) homeostasis.
      Title: Nitrate-Dependent Control of Shoot K Homeostasis by the Nitrate Transporter1/Peptide Transporter Family Member NPF7.3/NRT1.5 and the Stelar K+ Outward Rectifier SKOR in Arabidopsis.
    9. Data show that ethylene (ET) and jasmonic acid (JA)-nitrate transporters NRT1.8 and NRT1.5 signaling affect the crosstalk between stress-initiated nitrate allocation to roots (SINAR) and the environment.
      Title: The Arabidopsis ethylene/jasmonic acid-NRT signaling module coordinates nitrate reallocation and the trade-off between growth and environmental adaptation.
    10. NRT1.5 is involved in nitrate allocation to roots and the consequent tolerance to several stresses.
      Title: Arabidopsis NRT1.5 is another essential component in the regulation of nitrate reallocation and stress tolerance.
    Submit: New GeneRIF Correction See all GeneRIFs (11)

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_102980.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables nitrate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables potassium:proton antiporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within leaf senescence IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    NOT involved_in nitrate assimilation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within nitrate transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within potassium ion homeostasis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within potassium ion homeostasis IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within potassium ion homeostasis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within potassium ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within proton transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to nitrate IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    nitrate transporter 1.5
    NP_174523.2
    • nitrate transporter 1.5 (NRT1.5); CONTAINS InterPro DOMAIN/s: Oligopeptide transporter (InterPro:IPR000109), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: NITRATE TRANSPORTER 1.8 (TAIR:AT4G21680.1); Has 7755 Blast hits to 7381 proteins in 1434 species: Archae - 0; Bacteria - 3851; Metazoa - 707; Fungi - 433; Plants - 2214; Viruses - 0; Other Eukaryotes - 550 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      11715147..11719988 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102980.4 → NP_174523.2  nitrate transporter 1.5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174523.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LQL2
      UniProtKB/TrEMBL
      A0A178WGH3, A0A5S9WL26
      Conserved Domains (1) summary
      cd17419
      Location:41 → 580
      MFS_NPF7; NRT1/PTR family (NPF), subfamily 7 of the Major Facilitator Superfamily of transporters
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LQL2.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools