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    NFU1 NFU domain protein 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828196, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NFU1
    Official Full Name
    NFU domain protein 1
    Primary source
    TAIR:AT4G01940
    Locus tag
    AT4G01940
    See related
    Araport:AT4G01940
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtCNFU1; NFU domain protein 1; T7B11.20; T7B11_20
    Summary
    Encodes a protein containing the NFU domain that may be involved in iron-sulfur cluster assembly. Part of a five member gene family, more closely related to NFU2 and 3 than to NFU4 and 5. Targeted to the chloroplast.
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    Genomic context

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    See NFU1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (841989..843531, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Cysteine/Histidine-rich C1 domain family protein Neighboring gene insulin-induced protein Neighboring gene ncRNA Neighboring gene glycerol-3-phosphate acyltransferase 3 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The plastidial Arabidopsis thaliana NFU1 protein binds and delivers [4Fe-4S] clusters to specific client proteins. Roland M, et al. J Biol Chem, 2020 Feb 7. PMID 31911438, Free PMC Article
    2. Iron-sulfur protein NFU2 is required for branched-chain amino acid synthesis in Arabidopsis roots. Touraine B, et al. J Exp Bot, 2019 Mar 27. PMID 30785184
    3. The Arabidopsis chloroplastic NifU-like protein CnfU, which can act as an iron-sulfur cluster scaffold protein, is required for biogenesis of ferredoxin and photosystem I. Yabe T, et al. Plant Cell, 2004 Apr. PMID 15031412, Free PMC Article
    4. Iron-sulphur cluster assembly in plants: distinct NFU proteins in mitochondria and plastids from Arabidopsis thaliana. Léon S, et al. Biochem J, 2003 May 1. PMID 12553879, Free PMC Article
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_116425.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural molecule activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within chloroplast organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in iron-sulfur cluster assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within iron-sulfur cluster assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within iron-sulfur cluster assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    NFU domain protein 1
    NP_567219.1
    • NFU domain protein 1 (NFU1); CONTAINS InterPro DOMAIN/s: NIF system FeS cluster assembly, NifU, C-terminal (InterPro:IPR001075); BEST Arabidopsis thaliana protein match is: NIFU-like protein 2 (TAIR:AT5G49940.1); Has 4565 Blast hits to 4561 proteins in 1155 species: Archae - 11; Bacteria - 2225; Metazoa - 159; Fungi - 160; Plants - 186; Viruses - 3; Other Eukaryotes - 1821 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      841989..843531 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116425.3 → NP_567219.1  NFU domain protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567219.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93W77, Q9SYJ1
      UniProtKB/TrEMBL
      A0A178UZ12
      Conserved Domains (1) summary
      pfam01106
      Location:90 → 150
      NifU; NifU-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93W77.1

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