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    TGA4 TGACG motif-binding factor 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830866, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TGA4
    Official Full Name
    TGACG motif-binding factor 4
    Primary source
    TAIR:AT5G10030
    Locus tag
    AT5G10030
    See related
    Araport:AT5G10030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    OBF4; OCS BINDING ELEMENT 4; OCS ELEMENT BINDING FACTOR 4; OCTOPINE SYNTHASE ELEMENT-BINDING PROTEIN; T31P16.20; T31P16_20; TGACG motif-binding factor 4
    Summary
    Encodes a member of basic leucine zipper transcription gene family. Nomenclature according to Xiang, et al. (1997).
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    Genomic context

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    See TGA4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Sequence:
    Chromosome: 5; NC_003076.8 (3137289..3144269, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene myosin-H heavy protein Neighboring gene Leucine-rich receptor-like protein kinase family protein Neighboring gene uncharacterized protein Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene ENTH/VHS family protein Neighboring gene RNase L inhibitor protein-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AtTGA4, a bZIP transcription factor, confers drought resistance by enhancing nitrate transport and assimilation in Arabidopsis thaliana. Zhong L, et al. Biochem Biophys Res Commun, 2015 Feb 13. PMID 25596127
    2. Brassinosteroids enhance salicylic acid-mediated immune responses by inhibiting BIN2 phosphorylation of clade I TGA transcription factors in Arabidopsis. Kim YW, et al. Mol Plant, 2022 Jun 6. PMID 35524409
    3. Isolation and characterization of two related Arabidopsis ocs-element bZIP binding proteins. Zhang B, et al. Plant J, 1993 Oct. PMID 8252072
    4. Arabidopsis thaliana ethylene-responsive element binding protein (AtEBP), an ethylene-inducible, GCC box DNA-binding protein interacts with an ocs element binding protein. Büttner M, et al. Proc Natl Acad Sci U S A, 1997 May 27. PMID 9159183, Free PMC Article
    5. Systems approach identifies TGA1 and TGA4 transcription factors as important regulatory components of the nitrate response of Arabidopsis thaliana roots. Alvarez JM, et al. Plant J, 2014 Oct. PMID 25039575

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Clade I TGACG-Motif Binding Basic Leucine Zipper Transcription Factors Mediate BLADE-ON-PETIOLE-Dependent Regulation of Development.
      Title: Clade I TGACG-Motif Binding Basic Leucine Zipper Transcription Factors Mediate BLADE-ON-PETIOLE-Dependent Regulation of Development.
    2. Following drought stress there were higher nitrogen and proline contents in transgenic AtTGA4 plants than in wild type controls, and activity of the key enzyme nitrite reductase involved in nitrate assimilation processes was also higher.
      Title: AtTGA4, a bZIP transcription factor, confers drought resistance by enhancing nitrate transport and assimilation in Arabidopsis thaliana.
    3. TGA1 and TGA4 as important regulatory factors of the nitrate response in Arabidopsis roots.
      Title: Systems approach identifies TGA1 and TGA4 transcription factors as important regulatory components of the nitrate response of Arabidopsis thaliana roots.
    4. clade I TGA factors as positive regulators of one or more ER-related secretion pathways
      Title: Arabidopsis clade I TGA factors regulate apoplastic defences against the bacterial pathogen Pseudomonas syringae through endoplasmic reticulum-based processes.
    5. OBF4 can regulate flowering expression through the formation of a protein complex with CONSTANS
      Title: Isolation of CONSTANS as a TGA4/OBF4 interacting protein.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001203341.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within defense response to bacterium IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    TGACG motif-binding factor 4
    NP_001190270.1
    • TGACG motif-binding factor 4 (TGA4); CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: bZIP transcription factor family protein (TAIR:AT5G65210.5).
    NP_196565.1
    • TGACG motif-binding factor 4 (TGA4); FUNCTIONS IN: calmodulin binding, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: response to cold, defense response to bacterium; LOCATED IN: nucleus; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: bZIP transcription factor family protein (TAIR:AT5G65210.5); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      3137289..3144269 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121041.5 → NP_196565.1  TGACG motif-binding factor 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196565.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39162, Q9LX25
      UniProtKB/TrEMBL
      A0A178UQU7, A0A654FZU4, Q24JJ3
      Conserved Domains (3) summary
      cd14686
      Location:81 → 131
      bZIP; coiled coil [structural motif]
      pfam14144
      Location:166 → 240
      DOG1; Seed dormancy control
      cl21462
      Location:80 → 131
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

    2. NM_001343085.1 → NP_001330617.1  TGACG motif-binding factor 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39162, Q9LX25
      UniProtKB/TrEMBL
      A0A178UQU7, A0A654FZU4, Q24JJ3
      Conserved Domains (3) summary
      cd14686
      Location:81 → 131
      bZIP; coiled coil [structural motif]
      pfam14144
      Location:166 → 240
      DOG1; Seed dormancy control
      cl21462
      Location:80 → 131
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

    3. NM_001343084.1 → NP_001330616.1  TGACG motif-binding factor 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39162, Q9LX25
      UniProtKB/TrEMBL
      A0A178UQU7, A0A654FZU4, Q24JJ3
      Conserved Domains (3) summary
      cd14686
      Location:81 → 131
      bZIP; coiled coil [structural motif]
      pfam14144
      Location:166 → 240
      DOG1; Seed dormancy control
      cl21462
      Location:80 → 131
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

    4. NM_001343086.1 → NP_001330618.1  TGACG motif-binding factor 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39162, Q9LX25
      UniProtKB/TrEMBL
      A0A178UQU7, A0A654FZU4, Q24JJ3
      Conserved Domains (3) summary
      cd14686
      Location:81 → 131
      bZIP; coiled coil [structural motif]
      pfam14144
      Location:166 → 240
      DOG1; Seed dormancy control
      cl21462
      Location:80 → 131
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

    5. NM_001203341.1 → NP_001190270.1  TGACG motif-binding factor 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190270.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39162, Q9LX25
      UniProtKB/TrEMBL
      A0A178UQU7, A0A654FZU4, Q24JJ3
      Conserved Domains (3) summary
      cd14686
      Location:81 → 131
      bZIP; coiled coil [structural motif]
      pfam14144
      Location:166 → 240
      DOG1; Seed dormancy control
      cl21462
      Location:80 → 131
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39162.2

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