U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    MYB33 myb domain protein 33 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830497, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    MYB33
    Official Full Name
    myb domain protein 33
    Primary source
    TAIR:AT5G06100
    Locus tag
    AT5G06100
    See related
    Araport:AT5G06100
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATMYB33; K16F4.6; K16F4_6; myb domain protein 33
    Summary
    Encodes a member of the myb family of transcription factors (MYB33), contains Pfam profile: PF00249 myb DNA-binding domain. Double mutants with MYB65 are male sterile- anthers are small, pollen development is defective. Spatial expression appears to be under the control of miR159, contains a target site for this micro RNA. When the target site is mutated, expression is detected in leaves, roots, anther filament, pistil. The expression of a translational fusion is specific to anther locules in contrast to constructs lacking the miR159 target site. Phenotype is conditional and can be restored by lower temperature or higher light intensity.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See MYB33 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (1837835..1840727)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene LOB domain-containing protein 33 Neighboring gene glycerol-3-phosphate acyltransferase 7 Neighboring gene DnaJ and myb-like DNA-binding domain-containing protein Neighboring gene ARM repeat superfamily protein Neighboring gene tRNA-Leu

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Modulation of floral development by a gibberellin-regulated microRNA. Achard P, et al. Development, 2004 Jul. PMID 15226253
    2. The Arabidopsis GAMYB-like genes, MYB33 and MYB65, are microRNA-regulated genes that redundantly facilitate anther development. Millar AA, et al. Plant Cell, 2005 Mar. PMID 15722475, Free PMC Article
    3. Phosphorylation of CBP20 Links MicroRNA to Root Growth in the Ethylene Response. Zhang F, et al. PLoS Genet, 2016 Nov. PMID 27870849, Free PMC Article
    4. MicroRNAs with analogous target complementarities perform with highly variable efficacies in Arabidopsis. Deveson I, et al. FEBS Lett, 2013 Nov 15. PMID 24103298
    5. The microRNA159-regulated GAMYB-like genes inhibit growth and promote programmed cell death in Arabidopsis. Alonso-Peral MM, et al. Plant Physiol, 2010 Oct. PMID 20699403, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Primary root growth in Arabidopsis thaliana is inhibited by the miR159 mediated repression of MYB33, MYB65 and MYB101
      Title: Primary root growth in Arabidopsis thaliana is inhibited by the miR159 mediated repression of MYB33, MYB65 and MYB101.
    2. MiR159a and miR159b appear to continuously repress MYB33 and MYB65 expression to levels that have no major impact on rosette development.
      Title: Ubiquitous miR159 repression of MYB33/65 in Arabidopsis rosettes is robust and is not perturbed by a wide range of stresses.
    3. we proposed that ethylene regulated phosphorylation of CBP20 is involved in the root growth and one pathway is through the regulation of miR319b and its target MYB33 in roots
      Title: Phosphorylation of CBP20 Links MicroRNA to Root Growth in the Ethylene Response.
    4. There may be factors, in addition to complementarity, that control plant miRNA efficacy, such factors appear to be optimised in regards to the endogenous and ancient miR159:MYB33/65 relationship.
      Title: MicroRNAs with analogous target complementarities perform with highly variable efficacies in Arabidopsis.
    5. MYB33 and MYB65 play no part in gibberellin-mediated growth or flowering in vegetative tissues.
      Title: The microRNA159-regulated GAMYB-like genes inhibit growth and promote programmed cell death in Arabidopsis.
    6. Transformation with MYB33 containing the mutated microRNA target had dramatic pleiotrophic developmental defects, suggesting that restricting MYB33 expression, especially in the shoot apices, is essential for proper plant development.
      Title: The Arabidopsis GAMYB-like genes, MYB33 and MYB65, are microRNA-regulated genes that redundantly facilitate anther development.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_001085068.2
    NM_001342848.1
    NM_001342849.1
    NM_120692.3
    NM_180448.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anther development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in anther wall tapetum morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within gibberellic acid mediated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in negative regulation of cell population proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen sperm cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of abscisic acid-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of programmed cell death IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein storage vacuole organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to cytokinin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to ethylene IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to gibberellin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    myb domain protein 33
    NP_001078537.1
    • myb domain protein 33 (MYB33); CONTAINS InterPro DOMAIN/s: Transcription factor, GAMYB (InterPro:IPR016310), SANT, DNA-binding (InterPro:IPR001005), Myb, DNA-binding (InterPro:IPR014778), Homeodomain-like (InterPro:IPR009057), Myb transcription factor (InterPro:IPR015495), Homeodomain-related (InterPro:IPR012287), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930); BEST Arabidopsis thaliana protein match is: myb domain protein 65 (TAIR:AT3G11440.1); Has 8918 Blast hits to 8315 proteins in 480 species: Archae - 0; Bacteria - 0; Metazoa - 726; Fungi - 466; Plants - 5984; Viruses - 3; Other Eukaryotes - 1739 (source: NCBI BLink).
    NP_196228.1
    • myb domain protein 33 (MYB33); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 65 (TAIR:AT3G11440.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
    NP_850779.1
    • myb domain protein 33 (MYB33); CONTAINS InterPro DOMAIN/s: Transcription factor, GAMYB (InterPro:IPR016310), SANT, DNA-binding (InterPro:IPR001005), Myb, DNA-binding (InterPro:IPR014778), Homeodomain-like (InterPro:IPR009057), Myb transcription factor (InterPro:IPR015495), Homeodomain-related (InterPro:IPR012287), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930); BEST Arabidopsis thaliana protein match is: myb domain protein 65 (TAIR:AT3G11440.1); Has 8918 Blast hits to 8315 proteins in 480 species: Archae - 0; Bacteria - 0; Metazoa - 726; Fungi - 466; Plants - 5984; Viruses - 3; Other Eukaryotes - 1739 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      1837835..1840727
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180448.2 → NP_850779.1  myb domain protein 33 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850779.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A178UNH0, B2CUN6, Q8W1W6, Q9LHS6, Q9ZTE7
      UniProtKB/TrEMBL
      A0A1S5M0M7, A0A5S9Y1T9
      Conserved Domains (1) summary
      PLN03091
      Location:32 → 137
      PLN03091; hypothetical protein; Provisional

    2. NM_001085068.2 → NP_001078537.1  myb domain protein 33 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078537.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A178UNH0, B2CUN6, Q8W1W6, Q9LHS6, Q9ZTE7
      UniProtKB/TrEMBL
      A0A1S5M0M7, A0A5S9Y1T9
      Conserved Domains (1) summary
      PLN03091
      Location:32 → 137
      PLN03091; hypothetical protein; Provisional

    3. NM_001342848.1 → NP_001330997.1  myb domain protein 33 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A178UNH0, B2CUN6, Q8W1W6, Q9LHS6, Q9ZTE7
      UniProtKB/TrEMBL
      A0A1S5M0M7, A0A5S9Y1T9
      Conserved Domains (1) summary
      PLN03091
      Location:32 → 137
      PLN03091; hypothetical protein; Provisional

    4. NM_001342849.1 → NP_001330996.1  myb domain protein 33 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A178UNH0, B2CUN6, Q8W1W6, Q9LHS6, Q9ZTE7
      UniProtKB/TrEMBL
      A0A1S5M0M7, A0A5S9Y1T9
      Conserved Domains (1) summary
      PLN03091
      Location:32 → 137
      PLN03091; hypothetical protein; Provisional

    5. NM_120692.3 → NP_196228.1  myb domain protein 33 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196228.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8W1W6
      Conserved Domains (2) summary
      smart00717
      Location:87 → 134
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam00249
      Location:87 → 130
      Myb_DNA-binding; Myb-like DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8W1W6.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools