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    TAF4 TBP-associated factor 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834330, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TAF4
    Official Full Name
    TBP-associated factor 4
    Primary source
    TAIR:AT5G43130
    Locus tag
    AT5G43130
    See related
    Araport:AT5G43130
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MMG4.16; MMG4_16; TAF4B; TBP-associated factor 4; TBP-associated factor 4B
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    Genomic context

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    See TAF4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    15
    Sequence:
    Chromosome: 5; NC_003076.8 (17315326..17321231, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene pumilio 14 Neighboring gene ARM-repeat/Tetratricopeptide repeat (TPR)-like protein Neighboring gene Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein Neighboring gene elongation factor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Natural Variation in TBP-ASSOCIATED FACTOR 4b Controls Meiotic Crossover and Germline Transcription in Arabidopsis. Lawrence EJ, et al. Curr Biol, 2019 Aug 19. PMID 31378616
    2. αα-hub coregulator structure and flexibility determine transcription factor binding and selection in regulatory interactomes. Friis Theisen F, et al. J Biol Chem, 2022 Jun. PMID 35452682, Free PMC Article
    3. Substrates related to chromatin and to RNA-dependent processes are modified by Arabidopsis SUMO isoforms that differ in a conserved residue with influence on desumoylation. Budhiraja R, et al. Plant Physiol, 2009 Mar. PMID 19151129, Free PMC Article
    4. Yeast two-hybrid map of Arabidopsis TFIID. Lawit SJ, et al. Plant Mol Biol, 2007 May. PMID 17340043
    5. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001203529.1
    NM_001344473.1
    NM_123679.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    part_of transcription factor TFIID complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    TBP-associated factor 4
    NP_001190458.1
    • TBP-associated factor 4 (TAF4); FUNCTIONS IN: transcription initiation factor activity; INVOLVED IN: transcription initiation; LOCATED IN: transcription factor TFIID complex; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Transcription initiation factor TFIID component TAF4 (InterPro:IPR007900), RST domain of plant C-terminal (InterPro:IPR022003); BEST Arabidopsis thaliana protein match is: TBP-associated factor 4B (TAIR:AT1G27720.1).
    NP_199127.3
    • TBP-associated factor 4 (TAF4); FUNCTIONS IN: transcription initiation factor activity; INVOLVED IN: transcription initiation; LOCATED IN: transcription factor TFIID complex; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Transcription initiation factor TFIID component TAF4 (InterPro:IPR007900), RST domain of plant C-terminal (InterPro:IPR022003); BEST Arabidopsis thaliana protein match is: TBP-associated factor 4B (TAIR:AT1G27720.1); Has 4202 Blast hits to 2039 proteins in 267 species: Archae - 5; Bacteria - 117; Metazoa - 912; Fungi - 374; Plants - 141; Viruses - 12; Other Eukaryotes - 2641 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      17315326..17321231 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123679.4 → NP_199127.3  TBP-associated factor 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199127.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UC79, A0A5S9YB26
      Conserved Domains (2) summary
      pfam05236
      Location:537 → 821
      TAF4; Transcription initiation factor TFIID component TAF4 family
      pfam12174
      Location:187 → 250
      RST; RCD1-SRO-TAF4 (RST) plant domain

    2. NM_001344473.1 → NP_001330539.1  TBP-associated factor 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UC79, A0A1P8BB52, A0A5S9YB26

    3. NM_001203529.1 → NP_001190458.1  TBP-associated factor 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190458.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4K4L7, Q6SJR0, Q9FMH0
      UniProtKB/TrEMBL
      A0A178UC79, A0A5S9YB26
      Conserved Domains (3) summary
      pfam09606
      Location:82 → 529
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam05236
      Location:537 → 850
      TAF4; Transcription initiation factor TFIID component TAF4 family
      pfam12174
      Location:187 → 250
      RST; RCD1-SRO-TAF4 (RST) plant domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4K4L7.1

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