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    ADK1 adenylate kinase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836459, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ADK1
    Official Full Name
    adenylate kinase 1
    Primary source
    TAIR:AT5G63400
    Locus tag
    AT5G63400
    See related
    Araport:AT5G63400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    adenylate kinase 1; ADENYLATE KINASE 1; MLE2.3; MLE2_3
    Summary
    encodes a protein similar to adenylate kinase.
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    Genomic context

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    See ADK1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (25392920..25394907, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene AMP-dependent synthetase and ligase family protein Neighboring gene O-fucosyltransferase family protein Neighboring gene Leucine-rich repeat protein kinase family protein Neighboring gene RNA-metabolising metallo-beta-lactamase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Adenosine kinase modulates root gravitropism and cap morphogenesis in Arabidopsis. Young LS, et al. Plant Physiol, 2006 Oct. PMID 16891550, Free PMC Article
    2. Analysis of the Arabidopsis mitochondrial proteome. Millar AH, et al. Plant Physiol, 2001 Dec. PMID 11743115, Free PMC Article
    3. The hydrophobic proteome of mitochondrial membranes from Arabidopsis cell suspensions. Brugière S, et al. Phytochemistry, 2004 Jun. PMID 15276431
    4. Divalent metal ions in plant mitochondria and their role in interactions with proteins and oxidative stress-induced damage to respiratory function. Tan YF, et al. Plant Physiol, 2010 Feb. PMID 20018591, Free PMC Article
    5. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. a role for ADK and the S-adenosyl-L-methionine pathway in the control of root gravitropism and cap morphogenesis
      Title: Adenosine kinase modulates root gravitropism and cap morphogenesis in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001037052.2
    NM_125735.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables adenylate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables copper ion binding HDA PubMed 
    Component Evidence Code Pubs
    NOT located_in Golgi apparatus RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    adenylate kinase 1
    NP_001032129.1
    • adenylate kinase 1 (ADK1); FUNCTIONS IN: copper ion binding, adenylate kinase activity; INVOLVED IN: response to cadmium ion; LOCATED IN: mitochondrion, plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Adenylate kinase, active site lid domain (InterPro:IPR007862), Adenylate kinase (InterPro:IPR000850); BEST Arabidopsis thaliana protein match is: Adenylate kinase family protein (TAIR:AT5G50370.1); Has 14853 Blast hits to 14693 proteins in 5114 species: Archae - 98; Bacteria - 9957; Metazoa - 1251; Fungi - 476; Plants - 450; Viruses - 0; Other Eukaryotes - 2621 (source: NCBI BLink).
    NP_201145.1
    • adenylate kinase 1 (ADK1); FUNCTIONS IN: copper ion binding, adenylate kinase activity; INVOLVED IN: response to cadmium ion; LOCATED IN: mitochondrion, plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Adenylate kinase, active site lid domain (InterPro:IPR007862), Adenylate kinase, subfamily (InterPro:IPR006259), Adenylate kinase (InterPro:IPR000850); BEST Arabidopsis thaliana protein match is: Adenylate kinase family protein (TAIR:AT5G50370.1); Has 15080 Blast hits to 14911 proteins in 5099 species: Archae - 98; Bacteria - 9942; Metazoa - 1275; Fungi - 473; Plants - 468; Viruses - 0; Other Eukaryotes - 2824 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25392920..25394907 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125735.4 → NP_201145.1  adenylate kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201145.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82514, Q9FMW2
      UniProtKB/TrEMBL
      A0A178UAM7, A0A5S9YGN7, C0Z2D0
      Conserved Domains (1) summary
      PLN02674
      Location:3 → 246
      PLN02674; adenylate kinase

    2. NM_001037052.2 → NP_001032129.1  adenylate kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001032129.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4KAP2
      Conserved Domains (1) summary
      cd01428
      Location:35 → 172
      ADK; Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O82514.2

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