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Conserved domains on  [gi|79332010|ref|NP_001032129|]
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adenylate kinase 1 [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02674 super family cl31918
adenylate kinase
 3-185 4.24e-138

adenylate kinase


The actual alignment was detected with superfamily member PLN02674:

Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 385.01  E-value: 4.24e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010    3 TGGAAADLEDVQTVDLMSELLRRLKCSQKPDKRLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKA 82
Cdd:PLN02674   1 SSAAAANLEDVPSVDLMTELLRRMKCSSKPDKRLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   83 KEAMEKGELVSDDLVVGIIDEAMNKPKCQKGFILDGFPRTVTQAEKLDEMLKRRGTEIDKVLNFAIDDAILEERITGRWI 162
Cdd:PLN02674  81 KEAMDKGELVSDDLVVGIIDEAMKKPSCQKGFILDGFPRTVVQAQKLDEMLAKQGAKIDKVLNFAIDDAILEERITGRWI 160

                        170       180
                 ....*....|....*....|...
gi 79332010  163 HPSSGRSYHTKFAPPKTPGVDDM 185
Cdd:PLN02674 161 HPSSGRTYHTKFAPPKVPGVDDV 183
 
Name Accession Description Interval E-value
PLN02674 PLN02674
adenylate kinase
 3-185 4.24e-138

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 385.01  E-value: 4.24e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010    3 TGGAAADLEDVQTVDLMSELLRRLKCSQKPDKRLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKA 82
Cdd:PLN02674   1 SSAAAANLEDVPSVDLMTELLRRMKCSSKPDKRLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   83 KEAMEKGELVSDDLVVGIIDEAMNKPKCQKGFILDGFPRTVTQAEKLDEMLKRRGTEIDKVLNFAIDDAILEERITGRWI 162
Cdd:PLN02674  81 KEAMDKGELVSDDLVVGIIDEAMKKPSCQKGFILDGFPRTVVQAQKLDEMLAKQGAKIDKVLNFAIDDAILEERITGRWI 160

                        170       180
                 ....*....|....*....|...
gi 79332010  163 HPSSGRSYHTKFAPPKTPGVDDM 185
Cdd:PLN02674 161 HPSSGRTYHTKFAPPKVPGVDDV 183
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 35-184 2.85e-84

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 247.73  E-value: 2.85e-84
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010  35 RLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNKPKCQKGF 114
Cdd:COG0563   2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANGF 81

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010 115 ILDGFPRTVTQAEKLDEMLKRRGTEIDKVLNFAIDDAILEERITGRWIHPSSGRSYHTKFAPPKTPGVDD 184
Cdd:COG0563  82 ILDGFPRTVAQAEALDELLAELGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCD 151
ADK pfam00406
Adenylate kinase;
38-184 5.12e-83

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 243.37  E-value: 5.12e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010    38 FIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNKPKCQKGFILD 117
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCKNGFLLD 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 79332010   118 GFPRTVTQAEKLDEMLKrRGTEIDKVLNFAIDDAILEERITGRWIHPSSGRSYHTKFAPPKTPGVDD 184
Cdd:pfam00406  81 GFPRTVPQAEALEELLE-RGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDD 146
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 35-184 4.22e-78

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 232.12  E-value: 4.22e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010    35 RLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNK-PKCQKG 113
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQnDDNENG 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 79332010   114 FILDGFPRTVTQAEKLDEMLKRRgteIDKVLNFAIDDAILEERITGRWIHPSSGRSYHTKFAPPKTPGVDD 184
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDALLEEP---IDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDD 148
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 35-172 3.59e-72

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 216.33  E-value: 3.59e-72
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010  35 RLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNKPKCQKGF 114
Cdd:cd01428   1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKGF 80

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 79332010 115 ILDGFPRTVTQAEKLDEMLKrRGTEIDKVLNFAIDDAILEERITGRWIHPSSGRSYHT 172
Cdd:cd01428  81 ILDGFPRTVDQAEALDELLD-EGIKPDKVIELDVPDEVLIERILGRRICPVSGRVYHL 137
 
Name Accession Description Interval E-value
PLN02674 PLN02674
adenylate kinase
 3-185 4.24e-138

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 385.01  E-value: 4.24e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010    3 TGGAAADLEDVQTVDLMSELLRRLKCSQKPDKRLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKA 82
Cdd:PLN02674   1 SSAAAANLEDVPSVDLMTELLRRMKCSSKPDKRLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   83 KEAMEKGELVSDDLVVGIIDEAMNKPKCQKGFILDGFPRTVTQAEKLDEMLKRRGTEIDKVLNFAIDDAILEERITGRWI 162
Cdd:PLN02674  81 KEAMDKGELVSDDLVVGIIDEAMKKPSCQKGFILDGFPRTVVQAQKLDEMLAKQGAKIDKVLNFAIDDAILEERITGRWI 160

                        170       180
                 ....*....|....*....|...
gi 79332010  163 HPSSGRSYHTKFAPPKTPGVDDM 185
Cdd:PLN02674 161 HPSSGRTYHTKFAPPKVPGVDDV 183
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 35-184 2.85e-84

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 247.73  E-value: 2.85e-84
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010  35 RLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNKPKCQKGF 114
Cdd:COG0563   2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANGF 81

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010 115 ILDGFPRTVTQAEKLDEMLKRRGTEIDKVLNFAIDDAILEERITGRWIHPSSGRSYHTKFAPPKTPGVDD 184
Cdd:COG0563  82 ILDGFPRTVAQAEALDELLAELGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCD 151
ADK pfam00406
Adenylate kinase;
38-184 5.12e-83

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 243.37  E-value: 5.12e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010    38 FIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNKPKCQKGFILD 117
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCKNGFLLD 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 79332010   118 GFPRTVTQAEKLDEMLKrRGTEIDKVLNFAIDDAILEERITGRWIHPSSGRSYHTKFAPPKTPGVDD 184
Cdd:pfam00406  81 GFPRTVPQAEALEELLE-RGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDD 146
adk PRK00279
adenylate kinase; Reviewed
 34-184 1.20e-81

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 241.21  E-value: 1.20e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   34 KRLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNKPKCQKG 113
Cdd:PRK00279   1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNG 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 79332010  114 FILDGFPRTVTQAEKLDEMLKRRGTEIDKVLNFAIDDAILEERITGRWIHPSSGRSYHTKFAPPKTPGVDD 184
Cdd:PRK00279  81 FLLDGFPRTIPQAEALDEMLKELGIKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCD 151
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 35-184 4.22e-78

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 232.12  E-value: 4.22e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010    35 RLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNK-PKCQKG 113
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQnDDNENG 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 79332010   114 FILDGFPRTVTQAEKLDEMLKRRgteIDKVLNFAIDDAILEERITGRWIHPSSGRSYHTKFAPPKTPGVDD 184
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDALLEEP---IDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDD 148
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 35-172 3.59e-72

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 216.33  E-value: 3.59e-72
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010  35 RLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNKPKCQKGF 114
Cdd:cd01428   1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKGF 80

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 79332010 115 ILDGFPRTVTQAEKLDEMLKrRGTEIDKVLNFAIDDAILEERITGRWIHPSSGRSYHT 172
Cdd:cd01428  81 ILDGFPRTVDQAEALDELLD-EGIKPDKVIELDVPDEVLIERILGRRICPVSGRVYHL 137
adk PRK02496
adenylate kinase; Provisional
 34-160 3.89e-49

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 157.60  E-value: 3.89e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   34 KRLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNKPKCQKG 113
Cdd:PRK02496   2 TRLIFLGPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTPLGIKAQGYMDKGELVPDQLVLDLVQERLQQPDAANG 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 79332010  114 FILDGFPRTVTQAEKLDEMLKRRGTEIDKVLNFAIDDAILEERITGR 160
Cdd:PRK02496  82 WILDGFPRKVTQAAFLDELLQEIGQSGERVVNLDVPDDVVVERLLAR 128
PRK14528 PRK14528
adenylate kinase; Provisional
 34-169 1.06e-46

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 151.32  E-value: 1.06e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   34 KRLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNKPKCQKG 113
Cdd:PRK14528   2 KNIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKDRIREADCKNG 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 79332010  114 FILDGFPRTVTQAEKLDEMLKRRGTEIDKVLNFAIDDAILEERITGRWIhpSSGRS 169
Cdd:PRK14528  82 FLLDGFPRTVEQADALDALLKNEGKSIDKAINLEVPDGELLKRLLGRAE--IEGRA 135
PRK14532 PRK14532
adenylate kinase; Provisional
 36-160 5.78e-45

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 146.89  E-value: 5.78e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   36 LIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNKPKCQKGFI 115
Cdd:PRK14532   3 LILFGPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIEERLPEAEAAGGAI 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 79332010  116 LDGFPRTVTQAEKLDEMLKRRGTEIDKVLNFAIDDAILEERITGR 160
Cdd:PRK14532  83 FDGFPRTVAQAEALDKMLASRGQKIDVVIRLKVDDEALIERIVKR 127
PRK13808 PRK13808
adenylate kinase; Provisional
 35-160 5.80e-44

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 148.88  E-value: 5.80e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   35 RLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNKPKCQKGF 114
Cdd:PRK13808   2 RLILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPVGLKAKDIMASGGLVPDEVVVGIISDRIEQPDAANGF 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 79332010  115 ILDGFPRTVTQAEKLDEMLKRRGTEIDKVLNFAIDDAILEERITGR 160
Cdd:PRK13808  82 ILDGFPRTVPQAEALDALLKDKQLKLDAVVELRVNEGALLARVETR 127
PRK14531 PRK14531
adenylate kinase; Provisional
 35-160 3.84e-40

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 134.55  E-value: 3.84e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   35 RLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNKPKCQkGF 114
Cdd:PRK14531   4 RLLFLGPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSALGQEAEAVMNRGELVSDALVLAIVESQLKALNSG-GW 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 79332010  115 ILDGFPRTVTQAEKLDEMLKRRGTEIDKVLNFAIDDAILEERITGR 160
Cdd:PRK14531  83 LLDGFPRTVAQAEALEPLLEELKQPIEAVVLLELDDAVLIERLLAR 128
PRK14526 PRK14526
adenylate kinase; Provisional
 35-185 1.16e-36

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 126.50  E-value: 1.16e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   35 RLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNKPKCQKGF 114
Cdd:PRK14526   2 KLVFLGPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKEIKQIVENGQLVPDSITIKIVEDKINTIKNNDNF 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 79332010  115 ILDGFPRTVTQAEKLDEMLKRRgteidKVLNFAIDDAILEERITGRWIHPSSGRSYHTKFAPPKTPGVDDM 185
Cdd:PRK14526  82 ILDGFPRNINQAKALDKFLPNI-----KIINFLIDEELLIKRLSGRRICKSCNNIFNIYTLPTKEKGICDV 147
PRK14530 PRK14530
adenylate kinase; Provisional
 34-184 1.50e-36

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 126.44  E-value: 1.50e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   34 KRLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRA---------AVASKTPlgvkaKEAMEKGELVSDDLVVGIIDEA 104
Cdd:PRK14530   4 PRILLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALRAnkqmdisdmDTEYDTP-----GEYMDAGELVPDAVVNEIVEEA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010  105 MNKpkcQKGFILDGFPRTVTQAEKLDEMlkrrgTEIDKVLNFAIDDAILEERITGRWIHPSSGRSYHTKFAPPKTPGVDD 184
Cdd:PRK14530  79 LSD---ADGFVLDGYPRNLEQAEYLESI-----TDLDVVLYLDVSEEELVDRLTGRRVCPDCGANYHVEFNQPEEEGVCD 150
PLN02842 PLN02842
nucleotide kinase
 40-182 2.25e-35

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 129.21  E-value: 2.25e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   40 GPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNKPK-CQKGFILDG 118
Cdd:PLN02842   4 GAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGRLSREDaKEKGWLLDG 83

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 79332010  119 FPRTVTQAEKLDEMLKRrgTEIDKVLNfaIDDAILEERITGRWIHPSSGRSYHTKFAPPKTPGV 182
Cdd:PLN02842  84 YPRSFAQAQSLEKLKIR--PDIFILLD--VPDEILIDRCVGRRLDPVTGKIYHIKNFPPESEEI 143
PRK14527 PRK14527
adenylate kinase; Provisional
 29-160 7.02e-34

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 118.74  E-value: 7.02e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   29 SQKPDKRLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDE---AM 105
Cdd:PRK14527   2 TQTKNKVVIFLGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRDelaGM 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 79332010  106 NKPKCqkgfILDGFPRTVTQAEKLDEMLKRRGTEIDKVLNFAIDDAILEERITGR 160
Cdd:PRK14527  82 EPVRV----IFDGFPRTLAQAEALDRLLEELGARLLAVVLLEVPDEELIRRIVER 132
PRK14529 PRK14529
adenylate kinase; Provisional
 34-160 4.39e-32

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 115.20  E-value: 4.39e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   34 KRLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMnKPKCQKG 113
Cdd:PRK14529   1 MNILIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKKAKEYIDRGDLVPDDITIPMILETL-KQDGKNG 79

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 79332010  114 FILDGFPRTVTQAEKLDEMLKRRGTEIDKVLNFAIDDAILEERITGR 160
Cdd:PRK14529  80 WLLDGFPRNKVQAEKLWEALQKEGMKLDYVIEILLPREVAKNRIMGR 126
AAA_17 pfam13207
AAA domain;
40-170 1.12e-29

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 106.17  E-value: 1.12e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010    40 GPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTplGVKAKEAMEKGELVSDDLVVGIIDEAMNKPKCQKGFILDGF 119
Cdd:pfam13207   2 GVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAKERG--LVEDRDEMRKLPLEPQKELQKLAAERIAEEAGEGGVIVDGH 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 79332010   120 PRTVTQAEKLDEMLKRRGTEI--DKVLNFAID-DAILEERITGRwihpSSGRSY 170
Cdd:pfam13207  80 PRIKTPAGYLPGLPVEVLRELkpDAIILLEADpEEILERRLKDR----TRGRDD 129
PLN02459 PLN02459
probable adenylate kinase
 37-170 4.64e-28

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 105.70  E-value: 4.64e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   37 IFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNK--PKCQKGF 114
Cdd:PLN02459  33 VFLGCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLSKRLEAgeEEGESGF 112

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 79332010  115 ILDGFPRTVTQAEKLDEMlkrrgTEIDKVLNFAIDDAILEERITGRWIHPSSGRSY 170
Cdd:PLN02459 113 ILDGFPRTVRQAEILEGV-----TDIDLVVNLKLREEVLVEKCLGRRICSECGKNF 163
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 35-171 1.07e-27

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 103.73  E-value: 1.07e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   35 RLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNKP--KCQK 112
Cdd:PTZ00088   8 KIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIVKDEIAKVtdDCFK 87

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 79332010  113 GFILDGFPRTVTQAEKLDEMlkrrgTEIDKVLNFAIDDAILEERITGRWIHPSSGRSYH 171
Cdd:PTZ00088  88 GFILDGFPRNLKQCKELGKI-----TNIDLFVNIYLPRNILIKKLLGRRICNTCNRNFN 141
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 33-168 4.15e-27

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 101.43  E-value: 4.15e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010    33 DKRLIFI-GPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNKPK-C 110
Cdd:TIGR01360   2 KCKIIFIvGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAMVAALgT 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 79332010   111 QKGFILDGFPRTVTQAEKLDemlkRRGTEIDKVLNFAIDDAILEERITGRwiHPSSGR 168
Cdd:TIGR01360  82 SKGFLIDGYPREVKQGEEFE----RRIGPPTLVLYFDCSEDTMVKRLLKR--AETSGR 133
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 37-169 1.48e-21

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 86.66  E-value: 1.48e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010    37 IFI-GPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKtplGVKAKEAME----KGELVSDDLVVGIIDEAMNKPKCQ 111
Cdd:TIGR01359   2 VFVlGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIKRE---GSENGSLIEsyikEGKIVPSEVTVELLKKAIQEDGSS 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   112 KGFILDGFPRTvtqAEKLDEMLKRRGT--EIDKVLNFAIDDAILEERITGRwiHPSSGRS 169
Cdd:TIGR01359  79 KKFLIDGFPRN---EENLEAWEKLMDNkvNFKFVLFFDCPEETMIKRLLKR--GQTSGRV 133
PLN02200 PLN02200
adenylate kinase family protein
 18-189 2.79e-13

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 65.68  E-value: 2.79e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   18 LMSELLRRLKCSQKPDKRLIFI----GPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVS 93
Cdd:PLN02200  24 FSTEIITLEERGSSSKEKTPFItfvlGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEHGAMILNTIKEGKIVP 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010   94 DDLVVGIIDEAMNKPKCQKgFILDGFPRTVTQAEKLDEMLkrrGTEIDKVLNFAIDdailEERITGRWIHPSSGRsyhtk 173
Cdd:PLN02200 104 SEVTVKLIQKEMESSDNNK-FLIDGFPRTEENRIAFERII---GAEPNVVLFFDCP----EEEMVKRVLNRNQGR----- 170

                        170
                 ....*....|....*.
gi 79332010  174 fappktpgVDDMITLM 189
Cdd:PLN02200 171 --------VDDNIDTI 178
ADK_lid pfam05191
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular ...
 160-184 1.35e-08

Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organizms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function.


Pssm-ID: 461578 [Multi-domain]  Cd Length: 36  Bit Score: 48.61  E-value: 1.35e-08
                          10        20
                  ....*....|....*....|....*
gi 79332010   160 RWIHPSSGRSYHTKFAPPKTPGVDD 184
Cdd:pfam05191   1 RRVCPKCGRIYHVYFNPPKVEGVCD 25
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 40-118 1.83e-03

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 37.08  E-value: 1.83e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79332010  40 GPPGSGKGTQSPVVKDEYCLCHLSTGDMlraavasktplgvkakEAMEKGELVSDDLVVGIIDEAMNK----PKCQKGFI 115
Cdd:cd02020   6 GPAGSGKSTVAKLLAKKLGLPYLDTGGI----------------RTEEVGKLASEVAAIPEVRKALDErqreLAKKPGIV 69


                ...
gi 79332010 116 LDG 118
Cdd:cd02020  70 LEG 72
PRK09270 PRK09270
nucleoside triphosphate hydrolase domain-containing protein; Reviewed
 8-73 4.67e-03

nucleoside triphosphate hydrolase domain-containing protein; Reviewed


Pssm-ID: 236442  Cd Length: 229  Bit Score: 36.45  E-value: 4.67e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 79332010    8 ADLEDVQTVDLMSELLRRL-KCSQKPDKR-LIFI-GPPGSGKGTQSPvvkdeyCLCHLSTGDMLRAAVA 73
Cdd:PRK09270   5 AQYRDEEIEAVHKPLLRRLaALQAEPQRRtIVGIaGPPGAGKSTLAE------FLEALLQQDGELPAIQ 67
cyt_kin_arch TIGR02173
cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. ...
 40-75 4.96e-03

cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. Members of this family are found in the archaea and in spirochaetes, and differ considerably from the common bacterial form of cytidylate kinase described by TIGR00017.


Pssm-ID: 274012 [Multi-domain]  Cd Length: 171  Bit Score: 36.25  E-value: 4.96e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 79332010    40 GPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASK 75
Cdd:TIGR02173   7 GPPGSGKTTVAKILAEKLSLKLISAGDIFRELAAKM 42
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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