ufm1 ubiquitin-fold modifier 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ufm1provided by ZNC
Official Full Name: ubiquitin-fold modifier 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2930
See related: Ensembl:ENSDARG00000043857 AllianceGenome:ZFIN:ZDB-GENE-040426-2930
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ubfm1; BM-002; zgc:55335; wu:fa10f05; wu:fb72g01
Summary: Acts upstream of or within hematopoietic stem cell homeostasis and regulation of telomere maintenance. Predicted to be active in cytoplasm and nucleus. Is expressed in axis; hatching gland; notochord; and polster. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 14. Orthologous to human UFM1 (ubiquitin fold modifier 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	10	NC_007121.7 (25948172..25962058)
105	previous assembly	GRCz10 (GCF_000002035.5)	10	NC_007121.6 (25986459..26000345)

Chromosome 10 - NC_007121.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fd09f11.y1 (e-PCR)
- UniSTS:195079

fb72g01.x1 (e-PCR)
- UniSTS:187418

fa93a01.x1 (e-PCR)
- UniSTS:202575

fb72g01.x1 (e-PCR)
- UniSTS:191113

aa494589 (e-PCR)
- UniSTS:186792

fi13e09.x1 (e-PCR)
- UniSTS:196822

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within hematopoietic stem cell homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein K69-linked ufmylation	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within protein ufmylation	IEA Inferred from Electronic Annotation more info
involved_in protein ufmylation	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within regulation of telomere maintenance	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to endoplasmic reticulum stress	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to endoplasmic reticulum stress	ISS Inferred from Sequence or Structural Similarity more info
involved_in reticulophagy	IBA Inferred from Biological aspect of Ancestor more info
involved_in reticulophagy	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: ubiquitin-fold modifier 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.