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    ufm1 ubiquitin-fold modifier 1 [ Danio rerio (zebrafish) ]

    Gene ID: 322756, updated on 9-Dec-2024

    Summary

    Official Symbol
    ufm1provided by ZNC
    Official Full Name
    ubiquitin-fold modifier 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2930
    See related
    Ensembl:ENSDARG00000043857 AllianceGenome:ZFIN:ZDB-GENE-040426-2930
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ubfm1; BM-002; zgc:55335; wu:fa10f05; wu:fb72g01
    Summary
    Acts upstream of or within hematopoietic stem cell homeostasis and regulation of telomere maintenance. Predicted to be active in cytoplasm and nucleus. Is expressed in axis; hatching gland; notochord; and polster. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 14. Orthologous to human UFM1 (ubiquitin fold modifier 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ufm1 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (25948172..25962058)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (25986459..26000345)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene finTRIM family, member 54 Neighboring gene transient receptor potential cation channel, subfamily C, member 4a Neighboring gene large ribosomal subunit protein uL6-like Neighboring gene FRAS1 related extracellular matrix 2a Neighboring gene tripartite motif containing 47

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within hematopoietic stem cell homeostasis PubMed 
    involved_in protein K69-linked ufmylation  
    acts_upstream_of_or_within protein ufmylation  
    involved_in protein ufmylation  
    acts_upstream_of_or_within regulation of telomere maintenance PubMed 
    involved_in response to endoplasmic reticulum stress  
    involved_in response to endoplasmic reticulum stress  
    involved_in reticulophagy  
    involved_in reticulophagy  
    Component Evidence Code Pubs
    is_active_in cytoplasm  
    located_in cytoplasm  
    located_in cytoplasm  
    is_active_in nucleus  
    located_in nucleus  
    located_in nucleus  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212627.1NP_997792.1  ubiquitin-fold modifier 1

      See identical proteins and their annotated locations for NP_997792.1

      Status: PROVISIONAL

      Source sequence(s)
      AY394956
      UniProtKB/Swiss-Prot
      Q6TLE9, Q803Y4
      UniProtKB/TrEMBL
      A0A0R4I9C6
      Related
      ENSDARP00000064392.4, ENSDART00000064393.5
      Conserved Domains (1) summary
      cd01766
      Location:283
      Ufm1; Urm1-like ubiquitin domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      25948172..25962058
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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