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    PIP2;4 plasma membrane intrinsic protein 2;4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836187, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PIP2;4
    Official Full Name
    plasma membrane intrinsic protein 2;4
    Primary source
    TAIR:AT5G60660
    Locus tag
    AT5G60660
    See related
    Araport:AT5G60660
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MUP24.9; MUP24_9; PIP2F; plasma membrane intrinsic protein 2;4
    Summary
    A member of the plasma membrane intrinsic protein subfamily PIP2.When expressed in yeast cells can conduct hydrogen peroxide into those cells. Mutants exhibit longer root hairs.
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    Genomic context

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    See PIP2;4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (24375368..24377206, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene PDI-like 1-4 Neighboring gene proline-rich receptor-like kinase Neighboring gene ncRNA Neighboring gene Ribosomal protein L11 family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ca(2+)-activated anion channels and membrane depolarizations induced by blue light and cold in Arabidopsis seedlings. Lewis BD, et al. Plant Physiol, 1997 Aug. PMID 9276950, Free PMC Article
    2. Characterization of aquaporin-driven hydrogen peroxide transport. Wang H, et al. Biochim Biophys Acta Biomembr, 2020 Feb 1. PMID 31521632
    3. Plant plasma membrane water channels conduct the signalling molecule H2O2. Dynowski M, et al. Biochem J, 2008 Aug 15. PMID 18462192
    4. Coexpression-based clustering of Arabidopsis root genes predicts functional modules in early phosphate deficiency signaling. Lin WD, et al. Plant Physiol, 2011 Mar. PMID 21248074, Free PMC Article
    5. Interactomics of Qa-SNARE in Arabidopsis thaliana. Fujiwara M, et al. Plant Cell Physiol, 2014 Apr. PMID 24556609

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_125459.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables water channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within hydrogen peroxide transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within root hair elongation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within water transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    plasma membrane intrinsic protein 2;4
    NP_200874.1
    • plasma membrane intrinsic protein 2;4 (PIP2;4); FUNCTIONS IN: water channel activity; INVOLVED IN: transport, hydrogen peroxide transmembrane transport; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Aquaporin (InterPro:IPR012269), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: plasma membrane intrinsic protein 2 (TAIR:AT2G37170.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      24375368..24377206 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125459.4 → NP_200874.1  plasma membrane intrinsic protein 2;4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200874.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WQH7, Q9FF53
      UniProtKB/TrEMBL
      A0A178UG45, A0A5S9YG20
      Conserved Domains (1) summary
      pfam00230
      Location:31 → 266
      MIP; Major intrinsic protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FF53.1

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