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    CYSD2 cysteine synthase D2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832872, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CYSD2
    Official Full Name
    cysteine synthase D2
    Primary source
    TAIR:AT5G28020
    Locus tag
    AT5G28020
    See related
    Araport:AT5G28020
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCYSD2; CYSTEINE SYNTHASE; cysteine synthase D2; CYSTEINE SYNTHASE D2; F15F15.90; F15F15_90
    Summary
    Encodes cysteine synthase CysD2.
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    Genomic context

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    See CYSD2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Sequence:
    Chromosome: 5; NC_003076.8 (10026152..10028722, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Polyketide cyclase/dehydrase and lipid transport superfamily protein Neighboring gene Polyketide cyclase/dehydrase and lipid transport superfamily protein Neighboring gene L-cysteine desulfhydrase 1 Neighboring gene DNA-binding storekeeper protein-related transcriptional regulator

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Three Arabidopsis genes encoding proteins with differential activities for cysteine synthase and beta-cyanoalanine synthase. Yamaguchi Y, et al. Plant Cell Physiol, 2000 Apr. PMID 10845460
    2. The role of cyanoalanine synthase and alternative oxidase in promoting salt stress tolerance in Arabidopsis thaliana. Xu F, et al. BMC Plant Biol, 2023 Mar 27. PMID 36973660, Free PMC Article
    3. Analysis of the Arabidopsis O-acetylserine(thiol)lyase gene family demonstrates compartment-specific differences in the regulation of cysteine synthesis. Heeg C, et al. Plant Cell, 2008 Jan. PMID 18223034, Free PMC Article
    4. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The role of cyanoalanine synthase and alternative oxidase in promoting salt stress tolerance in Arabidopsis thaliana.
      Title: The role of cyanoalanine synthase and alternative oxidase in promoting salt stress tolerance in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001036879.2
    NM_001036880.3
    NM_001036881.1
    NM_001085159.1
    NM_122685.3
    NM_180756.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables L-3-cyanoalanine synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cysteine synthase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cysteine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cysteine biosynthetic process from serine IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    cysteine synthase D2
    NP_001031956.1
    • cysteine synthase D2 (CYSD2); FUNCTIONS IN: cysteine synthase activity; INVOLVED IN: cysteine biosynthetic process from serine, cysteine biosynthetic process, metabolic process; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site (InterPro:IPR001216), Cysteine synthase A (InterPro:IPR005859), Pyridoxal phosphate-dependent enzyme, beta subunit (InterPro:IPR001926), Cysteine synthase K/M (InterPro:IPR005856); BEST Arabidopsis thaliana protein match is: L-cysteine desulfhydrase 1 (TAIR:AT5G28030.1); Has 20008 Blast hits to 19993 proteins in 2660 species: Archae - 419; Bacteria - 13826; Metazoa - 355; Fungi - 603; Plants - 549; Viruses - 2; Other Eukaryotes - 4254 (source: NCBI BLink).
    NP_001031957.1
    • cysteine synthase D2 (CYSD2); FUNCTIONS IN: cysteine synthase activity; INVOLVED IN: cysteine biosynthetic process from serine, cysteine biosynthetic process, metabolic process; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site (InterPro:IPR001216), Cysteine synthase A (InterPro:IPR005859), Pyridoxal phosphate-dependent enzyme, beta subunit (InterPro:IPR001926), Cysteine synthase K/M (InterPro:IPR005856); BEST Arabidopsis thaliana protein match is: L-cysteine desulfhydrase 1 (TAIR:AT5G28030.1); Has 20103 Blast hits to 20088 proteins in 2683 species: Archae - 422; Bacteria - 13918; Metazoa - 355; Fungi - 603; Plants - 549; Viruses - 2; Other Eukaryotes - 4254 (source: NCBI BLink).
    NP_001031958.1
    • cysteine synthase D2 (CYSD2); FUNCTIONS IN: cysteine synthase activity; INVOLVED IN: cysteine biosynthetic process, metabolic process; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent enzyme, beta subunit (InterPro:IPR001926); BEST Arabidopsis thaliana protein match is: L-cysteine desulfhydrase 1 (TAIR:AT5G28030.1); Has 15181 Blast hits to 15173 proteins in 2614 species: Archae - 262; Bacteria - 10449; Metazoa - 258; Fungi - 501; Plants - 485; Viruses - 2; Other Eukaryotes - 3224 (source: NCBI BLink).
    NP_001078628.1
    • cysteine synthase D2 (CYSD2); FUNCTIONS IN: cysteine synthase activity; INVOLVED IN: cysteine biosynthetic process from serine, cysteine biosynthetic process, metabolic process; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site (InterPro:IPR001216), Cysteine synthase A (InterPro:IPR005859), Pyridoxal phosphate-dependent enzyme, beta subunit (InterPro:IPR001926), Cysteine synthase K/M (InterPro:IPR005856); BEST Arabidopsis thaliana protein match is: L-cysteine desulfhydrase 1 (TAIR:AT5G28030.1); Has 20008 Blast hits to 19993 proteins in 2660 species: Archae - 419; Bacteria - 13826; Metazoa - 355; Fungi - 603; Plants - 549; Viruses - 2; Other Eukaryotes - 4254 (source: NCBI BLink).
    NP_198154.1
    • cysteine synthase D2 (CYSD2); FUNCTIONS IN: cysteine synthase activity; INVOLVED IN: cysteine biosynthetic process from serine, cysteine biosynthetic process, metabolic process; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site (InterPro:IPR001216), Cysteine synthase A (InterPro:IPR005859), Pyridoxal phosphate-dependent enzyme, beta subunit (InterPro:IPR001926), Cysteine synthase K/M (InterPro:IPR005856); BEST Arabidopsis thaliana protein match is: L-cysteine desulfhydrase 1 (TAIR:AT5G28030.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
    NP_851087.1
    • cysteine synthase D2 (CYSD2); FUNCTIONS IN: cysteine synthase activity; INVOLVED IN: cysteine biosynthetic process from serine, cysteine biosynthetic process, metabolic process; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site (InterPro:IPR001216), Cysteine synthase A (InterPro:IPR005859), Pyridoxal phosphate-dependent enzyme, beta subunit (InterPro:IPR001926), Cysteine synthase K/M (InterPro:IPR005856); BEST Arabidopsis thaliana protein match is: L-cysteine desulfhydrase 1 (TAIR:AT5G28030.1); Has 20080 Blast hits to 20065 proteins in 2673 species: Archae - 419; Bacteria - 13898; Metazoa - 355; Fungi - 603; Plants - 549; Viruses - 2; Other Eukaryotes - 4254 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      10026152..10028722 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180756.3 → NP_851087.1  cysteine synthase D2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851087.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DHF3, Q8LEC3, Q9SMY4, Q9SXS7
      UniProtKB/TrEMBL
      A0A5S9Y802
      Conserved Domains (2) summary
      PLN02565
      Location:3 → 323
      PLN02565; cysteine synthase
      PLN00011
      Location:1 → 323
      PLN00011; cysteine synthase

    2. NM_001036880.3 → NP_001031957.1  cysteine synthase D2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031957.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DHF3, Q8LEC3, Q9SMY4, Q9SXS7
      UniProtKB/TrEMBL
      A0A5S9Y802
      Conserved Domains (2) summary
      PLN02565
      Location:3 → 323
      PLN02565; cysteine synthase
      PLN00011
      Location:1 → 323
      PLN00011; cysteine synthase

    3. NM_122685.3 → NP_198154.1  cysteine synthase D2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198154.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DHF3, Q8LEC3, Q9SMY4, Q9SXS7
      UniProtKB/TrEMBL
      A0A5S9Y802
      Conserved Domains (2) summary
      PLN02565
      Location:3 → 323
      PLN02565; cysteine synthase
      PLN00011
      Location:1 → 323
      PLN00011; cysteine synthase

    4. NM_001085159.1 → NP_001078628.1  cysteine synthase D2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078628.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DHF3, Q8LEC3, Q9SMY4, Q9SXS7
      UniProtKB/TrEMBL
      A0A5S9Y802
      Conserved Domains (2) summary
      PLN02565
      Location:3 → 323
      PLN02565; cysteine synthase
      PLN00011
      Location:1 → 323
      PLN00011; cysteine synthase

    5. NM_001036879.2 → NP_001031956.1  cysteine synthase D2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031956.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DHF3, Q8LEC3, Q9SMY4, Q9SXS7
      UniProtKB/TrEMBL
      A0A5S9Y802
      Conserved Domains (2) summary
      PLN02565
      Location:3 → 323
      PLN02565; cysteine synthase
      PLN00011
      Location:1 → 323
      PLN00011; cysteine synthase

    6. NM_001036881.1 → NP_001031958.1  cysteine synthase D2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031958.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4K5T1
      Conserved Domains (1) summary
      cl00342
      Location:1 → 237
      Trp-synth-beta_II; Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SXS7.1

    Gene LinkOut

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