U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    IMPA-2 importin alpha isoform 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827302, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    IMPA-2
    Official Full Name
    importin alpha isoform 2
    Primary source
    TAIR:AT4G16143
    Locus tag
    AT4G16143
    See related
    Araport:AT4G16143
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    importin alpha isoform 2
    Summary
    Protein interacts with Agrobacterium proteins VirD2 and VirE2. Is not individually essential for Agrobacterium-mediated root transformation, but when overexpressed can rescue the impa-4 decreased transformation susceptibility phenotype.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See IMPA-2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    10
    Sequence:
    Chromosome: 4; NC_003075.7 (9133750..9137415, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene proline-rich family protein Neighboring gene GATA type zinc finger transcription factor family protein Neighboring gene associated molecule with the SH3 domain of STAM 3 Neighboring gene cAMP-regulated phosphoprotein 19-related protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. SWO1 modulates cell wall integrity under salt stress by interacting with importin ɑ in Arabidopsis. Wang Z, et al. Stress Biol, 2021 Sep 29. PMID 37676567, Free PMC Article
    2. The intrinsically disordered N-terminal region of AtREM1.3 remorin protein mediates protein-protein interactions. Marín M, et al. J Biol Chem, 2012 Nov 16. PMID 23027878, Free PMC Article
    3. An Arabidopsis homolog of importin β1 is required for ABA response and drought tolerance. Luo Y, et al. Plant J, 2013 Aug. PMID 23582042
    4. CDKB1;1 forms a functional complex with CYCA2;3 to suppress endocycle onset. Boudolf V, et al. Plant Physiol, 2009 Jul. PMID 19458112, Free PMC Article
    5. A tandem affinity purification-based technology platform to study the cell cycle interactome in Arabidopsis thaliana. Van Leene J, et al. Mol Cell Proteomics, 2007 Jul. PMID 17426018

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_001160767.2
    NM_117708.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables nuclear import signal receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein import into nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in nucleolus HDA PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    importin alpha isoform 2
    NP_001154239.1
    • importin alpha isoform 2 (IMPA-2); FUNCTIONS IN: protein transporter activity, binding; INVOLVED IN: intracellular protein transport, protein import into nucleus; LOCATED IN: cytosol; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Importin-alpha-like, importin-beta-binding domain (InterPro:IPR002652), Armadillo-like helical (InterPro:IPR011989), Armadillo (InterPro:IPR000225), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: importin alpha isoform 1 (TAIR:AT3G06720.2); Has 4654 Blast hits to 3364 proteins in 293 species: Archae - 4; Bacteria - 33; Metazoa - 1869; Fungi - 640; Plants - 1336; Viruses - 0; Other Eukaryotes - 772 (source: NCBI BLink).
    NP_567485.4
    • importin alpha isoform 2 (IMPA-2); FUNCTIONS IN: protein transporter activity, binding; INVOLVED IN: intracellular protein transport, protein import into nucleus; LOCATED IN: cytosol, nucleolus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Importin-alpha-like, importin-beta-binding domain (InterPro:IPR002652), Armadillo-like helical (InterPro:IPR011989), Armadillo (InterPro:IPR000225), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: importin alpha isoform 1 (TAIR:AT3G06720.2); Has 4654 Blast hits to 3364 proteins in 293 species: Archae - 4; Bacteria - 33; Metazoa - 1869; Fungi - 640; Plants - 1336; Viruses - 0; Other Eukaryotes - 772 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      9133750..9137415 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117708.6 → NP_567485.4  importin alpha isoform 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567485.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JL11, O49600, Q9ASV4
      UniProtKB/TrEMBL
      A0A178V0W7
      Conserved Domains (4) summary
      COG5064
      Location:10 → 535
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00020
      Location:114 → 235
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam01749
      Location:8 → 99
      IBB; Importin beta binding domain
      sd00043
      Location:116 → 148
      ARM; armadillo repeat [structural motif]

    2. NM_001160767.2 → NP_001154239.1  importin alpha isoform 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001154239.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JL11, O49600, Q9ASV4
      UniProtKB/TrEMBL
      A0A178V0W7
      Conserved Domains (4) summary
      COG5064
      Location:10 → 535
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00020
      Location:114 → 235
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam01749
      Location:8 → 99
      IBB; Importin beta binding domain
      sd00043
      Location:116 → 148
      ARM; armadillo repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4JL11.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.