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    Tmem144 transmembrane protein 144 [ Mus musculus (house mouse) ]

    Gene ID: 70652, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Tmem144provided by MGI
    Official Full Name
    transmembrane protein 144provided by MGI
    Primary source
    MGI:MGI:1917902
    See related
    Ensembl:ENSMUSG00000027956 AllianceGenome:MGI:1917902
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110057I03Rik; 5730537D05Rik
    Summary
    Predicted to enable carbohydrate transmembrane transporter activity. Predicted to be involved in carbohydrate transmembrane transport. Predicted to be located in membrane. Orthologous to human TMEM144 (transmembrane protein 144). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 23.7), placenta adult (RPKM 5.3) and 6 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tmem144 in Genome Data Viewer
    Location:
    3 E3; 3 35.07 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (79719871..79760093, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (79812564..79852787, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930579G24 gene Neighboring gene STARR-seq mESC enhancer starr_08007 Neighboring gene VISTA enhancer mm1650 Neighboring gene relaxin/insulin-like family peptide receptor 1 Neighboring gene STARR-seq mESC enhancer starr_08009 Neighboring gene STARR-positive B cell enhancer ABC_E3438 Neighboring gene predicted gene, 26420 Neighboring gene STARR-seq mESC enhancer starr_08010 Neighboring gene STARR-seq mESC enhancer starr_08011 Neighboring gene STARR-seq mESC enhancer starr_08012 Neighboring gene golgi associated kinase 1B Neighboring gene STARR-seq mESC enhancer starr_08013 Neighboring gene VISTA enhancer mm1052 Neighboring gene STARR-seq mESC enhancer starr_08014 Neighboring gene STARR-seq mESC enhancer starr_08015 Neighboring gene RIKEN cDNA A330069K06 gene Neighboring gene STARR-seq mESC enhancer starr_08016 Neighboring gene eukaryotic translation initiation factor 3, subunit M pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables carbohydrate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in carbohydrate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 144

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001379542.1 → NP_001366471.1  transmembrane protein 144 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2), as well as variants 1 and 3, encodes isoform a.
      Source sequence(s)
      AC159281
      UniProtKB/Swiss-Prot
      Q8VEH0, Q9CYC7
      Related
      ENSMUSP00000127837.2, ENSMUST00000168038.8
      Conserved Domains (1) summary
      cl19288
      Location:9 → 347
      RhaT; L-rhamnose-proton symport protein (RhaT)

    2. NM_001379543.1 → NP_001366472.1  transmembrane protein 144 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3), as well as variants 1 and 2, encodes isoform a.
      Source sequence(s)
      AC159281
      UniProtKB/Swiss-Prot
      Q8VEH0, Q9CYC7
      Conserved Domains (1) summary
      cl19288
      Location:9 → 347
      RhaT; L-rhamnose-proton symport protein (RhaT)

    3. NM_001379544.1 → NP_001366473.1  transmembrane protein 144 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC159281
      Conserved Domains (1) summary
      cl19288
      Location:1 → 125
      RhaT; L-rhamnose-proton symport protein (RhaT)

    4. NM_027495.5 → NP_081771.2  transmembrane protein 144 isoform a

      See identical proteins and their annotated locations for NP_081771.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1-3 all encode the same isoform (a).
      Source sequence(s)
      AC159281
      Consensus CDS
      CCDS17421.1
      UniProtKB/Swiss-Prot
      Q8VEH0, Q9CYC7
      Related
      ENSMUSP00000029568.2, ENSMUST00000029568.7
      Conserved Domains (1) summary
      cl19288
      Location:9 → 347
      RhaT; L-rhamnose-proton symport protein (RhaT)

    RNA

    1. NR_166772.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC159281

    2. NR_166773.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC159281

    3. NR_166774.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC159281

    4. NR_166775.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC159281

    5. NR_166776.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC159281

    6. NR_166777.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC159281

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      79719871..79760093 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006502059.5 → XP_006502122.1  transmembrane protein 144 isoform X1

      See identical proteins and their annotated locations for XP_006502122.1

      UniProtKB/Swiss-Prot
      Q8VEH0, Q9CYC7
      Conserved Domains (1) summary
      cl19288
      Location:9 → 347
      RhaT; L-rhamnose-proton symport protein (RhaT)

    2. XM_006502058.5 → XP_006502121.1  transmembrane protein 144 isoform X1

      See identical proteins and their annotated locations for XP_006502121.1

      UniProtKB/Swiss-Prot
      Q8VEH0, Q9CYC7
      Conserved Domains (1) summary
      cl19288
      Location:9 → 347
      RhaT; L-rhamnose-proton symport protein (RhaT)

    3. XM_030252816.2 → XP_030108676.1  transmembrane protein 144 isoform X2

      Conserved Domains (1) summary
      cl19288
      Location:1 → 186
      RhaT; L-rhamnose-proton symport protein (RhaT)

    4. XM_036163306.1 → XP_036019199.1  transmembrane protein 144 isoform X1

      UniProtKB/Swiss-Prot
      Q8VEH0, Q9CYC7
      Conserved Domains (1) summary
      cl19288
      Location:9 → 347
      RhaT; L-rhamnose-proton symport protein (RhaT)

    5. XM_036163305.1 → XP_036019198.1  transmembrane protein 144 isoform X1

      UniProtKB/Swiss-Prot
      Q8VEH0, Q9CYC7
      Conserved Domains (1) summary
      cl19288
      Location:9 → 347
      RhaT; L-rhamnose-proton symport protein (RhaT)

    RNA

    1. XR_001783743.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VEH0.1 GenPept UniProtKB/Swiss-Prot:Q8VEH0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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