ccdc65 coiled-coil domain containing 65 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ccdc65provided by ZNC
Official Full Name: coiled-coil domain containing 65provided by ZNC
Primary source: ZFIN:ZDB-GENE-030616-358
See related: Ensembl:ENSDARG00000032005 AllianceGenome:ZFIN:ZDB-GENE-030616-358
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: NYD-SP28; zgc:92302; si:dz202l16.3; si:busm1-202l16.3
Summary: Acts upstream of or within regulation of cilium movement. Predicted to be located in cytoplasm; cytoskeleton; and motile cilium. Predicted to be part of axonemal dynein complex. Predicted to be active in axoneme. Is expressed in pronephric duct and spinal cord. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 27. Orthologous to human CCDC65 (coiled-coil domain containing 65). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (7395019..7428197)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (7263676..7270350)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in axonemal dynein complex assembly	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within axonemal dynein complex assembly	IEA Inferred from Electronic Annotation more info
involved_in cilium-dependent cell motility	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of cilium movement	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of cilium movement	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of axonemal dynein complex	IEA Inferred from Electronic Annotation more info
is_active_in axoneme	IBA Inferred from Biological aspect of Ancestor more info
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in cilium	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in motile cilium	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: dynein regulatory complex subunit 2

Names: coiled-coil domain-containing protein 65

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.